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Items: 1 to 20 of 226

1.

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.

Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S.

Nature. 2008 Nov 13;456(7219):264-8. doi: 10.1038/nature07383. Epub 2008 Oct 5.

PMID:
18849965
2.

Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2.

Plantinga TS, Crisan TO, Oosting M, van de Veerdonk FL, de Jong DJ, Philpott DJ, van der Meer JW, Girardin SE, Joosten LA, Netea MG.

Gut. 2011 Sep;60(9):1229-35. doi: 10.1136/gut.2010.228908. Epub 2011 Mar 15.

PMID:
21406388
3.

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome.

Bauer C, Duewell P, Mayer C, Lehr HA, Fitzgerald KA, Dauer M, Tschopp J, Endres S, Latz E, Schnurr M.

Gut. 2010 Sep;59(9):1192-9. doi: 10.1136/gut.2009.197822. Epub 2010 May 4.

PMID:
20442201
4.

The bile acid receptor FXR is a modulator of intestinal innate immunity.

Vavassori P, Mencarelli A, Renga B, Distrutti E, Fiorucci S.

J Immunol. 2009 Nov 15;183(10):6251-61. doi: 10.4049/jimmunol.0803978. Epub 2009 Oct 28.

5.

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages.

Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, Yoshikawa Y, Mimuro H, Inohara N, Sasakawa C, Nuñez G.

PLoS Pathog. 2007 Aug 10;3(8):e111.

6.

Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8.

Maelfait J, Vercammen E, Janssens S, Schotte P, Haegman M, Magez S, Beyaert R.

J Exp Med. 2008 Sep 1;205(9):1967-73. doi: 10.1084/jem.20071632. Epub 2008 Aug 25.

7.

Tumor suppressor death-associated protein kinase is required for full IL-1β production.

Chuang YT, Lin YC, Lin KH, Chou TF, Kuo WC, Yang KT, Wu PR, Chen RH, Kimchi A, Lai MZ.

Blood. 2011 Jan 20;117(3):960-70. doi: 10.1182/blood-2010-08-303115. Epub 2010 Nov 1.

8.

Classification of genetic profiles of Crohn's disease: a focus on the ATG16L1 gene.

Grant SF, Baldassano RN, Hakonarson H.

Expert Rev Mol Diagn. 2008 Mar;8(2):199-207. doi: 10.1586/14737159.8.2.199. Review.

PMID:
18366306
9.

The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells.

Ropolo A, Grasso D, Pardo R, Sacchetti ML, Archange C, Lo Re A, Seux M, Nowak J, Gonzalez CD, Iovanna JL, Vaccaro MI.

J Biol Chem. 2007 Dec 21;282(51):37124-33. Epub 2007 Oct 16.

10.

Autophagy is required for toll-like receptor-mediated interleukin-8 production in intestinal epithelial cells.

Li YY, Ishihara S, Aziz MM, Oka A, Kusunoki R, Tada Y, Yuki T, Amano Y, Ansary MU, Kinoshita Y.

Int J Mol Med. 2011 Mar;27(3):337-44. doi: 10.3892/ijmm.2011.596. Epub 2011 Jan 11.

PMID:
21225224
11.

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

Kouroku Y, Fujita E, Tanida I, Ueno T, Isoai A, Kumagai H, Ogawa S, Kaufman RJ, Kominami E, Momoi T.

Cell Death Differ. 2007 Feb;14(2):230-9. Epub 2006 Jun 23.

12.

Is there a role for Crohn's disease-associated autophagy genes ATG16L1 and IRGM in formation of granulomas?

Wolfkamp SC, Te Velde AA, Weersma RK, Ponsioen CY, Stokkers PC.

Eur J Gastroenterol Hepatol. 2010 Aug;22(8):933-7. doi: 10.1097/MEG.0b013e32833775e6.

PMID:
20395867
13.

Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans.

van de Veerdonk FL, Joosten LA, Devesa I, Mora-Montes HM, Kanneganti TD, Dinarello CA, van der Meer JW, Gow NA, Kullberg BJ, Netea MG.

J Infect Dis. 2009 Apr 1;199(7):1087-96. doi: 10.1086/597274. Erratum in: J Infect Dis. 2009 Jun 1;199(11):1716.

15.

Signal-transducing mechanisms of ketamine-caused inhibition of interleukin-1 beta gene expression in lipopolysaccharide-stimulated murine macrophage-like Raw 264.7 cells.

Chen TL, Chang CC, Lin YL, Ueng YF, Chen RM.

Toxicol Appl Pharmacol. 2009 Oct 1;240(1):15-25. doi: 10.1016/j.taap.2009.06.013. Epub 2009 Jun 21.

PMID:
19540866
16.

Biphasic regulation of levofloxacin on lipopolysaccharide-induced IL-1beta production.

Kitazawa T, Nakayama K, Okugawa S, Koike K, Shibasaki Y, Ota Y.

Life Sci. 2007 Apr 3;80(17):1572-7. Epub 2007 Jan 23.

PMID:
17300811
17.

Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process.

Giamarellos-Bourboulis EJ, Mouktaroudi M, Bodar E, van der Ven J, Kullberg BJ, Netea MG, van der Meer JW.

Ann Rheum Dis. 2009 Feb;68(2):273-8. doi: 10.1136/ard.2007.082222. Epub 2008 Apr 4.

PMID:
18390571
18.

Activating cannabinoid receptor 2 alleviates pathogenesis of experimental autoimmune encephalomyelitis via activation of autophagy and inhibiting NLRP3 inflammasome.

Shao BZ, Wei W, Ke P, Xu ZQ, Zhou JX, Liu C.

CNS Neurosci Ther. 2014 Dec;20(12):1021-8. doi: 10.1111/cns.12349.

PMID:
25417929
19.

A Crohn's disease variant in Atg16l1 enhances its degradation by caspase 3.

Murthy A, Li Y, Peng I, Reichelt M, Katakam AK, Noubade R, Roose-Girma M, DeVoss J, Diehl L, Graham RR, van Lookeren Campagne M.

Nature. 2014 Feb 27;506(7489):456-62. doi: 10.1038/nature13044. Epub 2014 Feb 19.

PMID:
24553140
20.
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