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Results: 1 to 20 of 157

1.

Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.

Shen CH, Chen HY, Lin MS, Li FY, Chang CC, Kuo ML, Settleman J, Chen RH.

Cancer Res. 2008 Oct 1;68(19):7779-87. doi: 10.1158/0008-5472.CAN-08-0997.

PMID:
18829532
[PubMed - indexed for MEDLINE]
Free Article
2.

Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin.

Chen HY, Shen CH, Tsai YT, Lin FC, Huang YP, Chen RH.

Mol Cell Biol. 2004 Dec;24(24):10558-72.

PMID:
15572663
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion.

Zrihan-Licht S, Fu Y, Settleman J, Schinkmann K, Shaw L, Keydar I, Avraham S, Avraham H.

Oncogene. 2000 Mar 2;19(10):1318-28.

PMID:
10713673
[PubMed - indexed for MEDLINE]
Free Article
4.

Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6.

Weaver AM, Silva CM.

Breast Cancer Res. 2007;9(6):R79.

PMID:
17997837
[PubMed - indexed for MEDLINE]
Free PMC Article
5.
6.

Inactivation of Rho GTPases by p190 RhoGAP reduces human pancreatic cancer cell invasion and metastasis.

Kusama T, Mukai M, Endo H, Ishikawa O, Tatsuta M, Nakamura H, Inoue M.

Cancer Sci. 2006 Sep;97(9):848-53. Epub 2006 Jun 14.

PMID:
16776779
[PubMed - indexed for MEDLINE]
7.

A novel strategy for specifically down-regulating individual Rho GTPase activity in tumor cells.

Wang L, Yang L, Luo Y, Zheng Y.

J Biol Chem. 2003 Nov 7;278(45):44617-25. Epub 2003 Aug 25.

PMID:
12939257
[PubMed - indexed for MEDLINE]
Free Article
8.

BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest.

Lukong KE, Huot ME, Richard S.

Cell Signal. 2009 Sep;21(9):1415-22. doi: 10.1016/j.cellsig.2009.04.008. Epub 2009 May 9.

PMID:
19439179
[PubMed - indexed for MEDLINE]
9.

HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition.

Wu X, Chen H, Parker B, Rubin E, Zhu T, Lee JS, Argani P, Sukumar S.

Cancer Res. 2006 Oct 1;66(19):9527-34.

PMID:
17018609
[PubMed - indexed for MEDLINE]
Free Article
10.

Breast tumor kinase and extracellular signal-regulated kinase 5 mediate Met receptor signaling to cell migration in breast cancer cells.

Castro NE, Lange CA.

Breast Cancer Res. 2010;12(4):R60. doi: 10.1186/bcr2622. Epub 2010 Aug 5.

PMID:
20687930
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.

Bradley WD, Hernández SE, Settleman J, Koleske AJ.

Mol Biol Cell. 2006 Nov;17(11):4827-36. Epub 2006 Sep 13.

PMID:
16971514
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Hyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasion.

Bourguignon LY, Wong G, Earle C, Krueger K, Spevak CC.

J Biol Chem. 2010 Nov 19;285(47):36721-35. doi: 10.1074/jbc.M110.162305. Epub 2010 Sep 15.

PMID:
20843787
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Coupling of RAFTK/Pyk2 kinase with c-Abl and their role in the migration of breast cancer cells.

Zrihan-Licht S, Avraham S, Jiang S, Fu Y, Avraham HK.

Int J Oncol. 2004 Jan;24(1):153-9.

PMID:
14654952
[PubMed - indexed for MEDLINE]
14.

Thy-1 regulates fibroblast focal adhesions, cytoskeletal organization and migration through modulation of p190 RhoGAP and Rho GTPase activity.

Barker TH, Grenett HE, MacEwen MW, Tilden SG, Fuller GM, Settleman J, Woods A, Murphy-Ullrich J, Hagood JS.

Exp Cell Res. 2004 May 1;295(2):488-96.

PMID:
15093746
[PubMed - indexed for MEDLINE]
15.

Breast tumor kinase BRK requires kinesin-2 subunit KAP3A in modulation of cell migration.

Lukong KE, Richard S.

Cell Signal. 2008 Feb;20(2):432-42. Epub 2007 Nov 13.

PMID:
18077133
[PubMed - indexed for MEDLINE]
16.

Tyrosine phosphorylation of sam68 by breast tumor kinase regulates intranuclear localization and cell cycle progression.

Lukong KE, Larocque D, Tyner AL, Richard S.

J Biol Chem. 2005 Nov 18;280(46):38639-47. Epub 2005 Sep 22.

PMID:
16179349
[PubMed - indexed for MEDLINE]
Free Article
17.

Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells.

Ostrander JH, Daniel AR, Lofgren K, Kleer CG, Lange CA.

Cancer Res. 2007 May 1;67(9):4199-209.

PMID:
17483331
[PubMed - indexed for MEDLINE]
Free Article
18.

Aberrant Ras regulation and reduced p190 tyrosine phosphorylation in cells lacking p120-Gap.

van der Geer P, Henkemeyer M, Jacks T, Pawson T.

Mol Cell Biol. 1997 Apr;17(4):1840-7.

PMID:
9121432
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

c-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation.

Chang JH, Gill S, Settleman J, Parsons SJ.

J Cell Biol. 1995 Jul;130(2):355-68.

PMID:
7542246
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Brk/PTK6 cooperates with HER2 and Src in regulating breast cancer cell survival and epithelial-to-mesenchymal transition.

Ai M, Liang K, Lu Y, Qiu S, Fan Z.

Cancer Biol Ther. 2013 Mar;14(3):237-45. doi: 10.4161/cbt.23295. Epub 2013 Jan 4.

PMID:
23291984
[PubMed - indexed for MEDLINE]
Free PMC Article

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