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Results: 1 to 20 of 115

1.

Chemical probes for histone-modifying enzymes.

Cole PA.

Nat Chem Biol. 2008 Oct;4(10):590-7. doi: 10.1038/nchembio.111. Review.

PMID:
18800048
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Histone modification enzymes: novel targets for cancer drugs.

Kristeleit R, Stimson L, Workman P, Aherne W.

Expert Opin Emerg Drugs. 2004 May;9(1):135-54. Review.

PMID:
15155140
[PubMed - indexed for MEDLINE]
3.

Small molecule modulators of histone acetylation and methylation: a disease perspective.

Selvi BR, Mohankrishna DV, Ostwal YB, Kundu TK.

Biochim Biophys Acta. 2010 Oct-Dec;1799(10-12):810-28. doi: 10.1016/j.bbagrm.2010.09.005. Epub 2010 Oct 1. Review.

PMID:
20888936
[PubMed - indexed for MEDLINE]
Free Article
4.

Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview.

Eglen RM, Reisine T.

J Biomol Screen. 2011 Dec;16(10):1137-52. doi: 10.1177/1087057111417871. Epub 2011 Oct 14. Review.

PMID:
22002420
[PubMed - indexed for MEDLINE]
5.

Chemistry of acetyl transfer by histone modifying enzymes: structure, mechanism and implications for effector design.

Hodawadekar SC, Marmorstein R.

Oncogene. 2007 Aug 13;26(37):5528-40. Review.

PMID:
17694092
[PubMed - indexed for MEDLINE]
6.

Epi-drugs to fight cancer: from chemistry to cancer treatment, the road ahead.

Mai A, Altucci L.

Int J Biochem Cell Biol. 2009 Jan;41(1):199-213. doi: 10.1016/j.biocel.2008.08.020. Epub 2008 Aug 22. Review.

PMID:
18790076
[PubMed - indexed for MEDLINE]
7.

Histone deacetylase inhibitors: molecular and biological activity as a premise to clinical application.

Santini V, Gozzini A, Ferrari G.

Curr Drug Metab. 2007 May;8(4):383-93. Review.

PMID:
17504226
[PubMed - indexed for MEDLINE]
8.

Structural and chemical basis of histone acetylation.

Marmorstein R.

Novartis Found Symp. 2004;259:78-98; discussion 98-101, 163-9. Review.

PMID:
15171248
[PubMed - indexed for MEDLINE]
9.

Structure and activity of enzymes that remove histone modifications.

Holbert MA, Marmorstein R.

Curr Opin Struct Biol. 2005 Dec;15(6):673-80. Epub 2005 Nov 2. Review.

PMID:
16263263
[PubMed - indexed for MEDLINE]
10.

Histone acetylation: plants and fungi as model systems for the investigation of histone deacetylases.

Graessle S, Loidl P, Brosch G.

Cell Mol Life Sci. 2001 May;58(5-6):704-20. Review.

PMID:
11437232
[PubMed - indexed for MEDLINE]
11.

Histone acetylation and methylation: combinatorial players for transcriptional regulation.

An W.

Subcell Biochem. 2007;41:351-69. Review.

PMID:
17484136
[PubMed - indexed for MEDLINE]
12.

Histone deacetylation in epigenetics: an attractive target for anticancer therapy.

Mai A, Massa S, Rotili D, Cerbara I, Valente S, Pezzi R, Simeoni S, Ragno R.

Med Res Rev. 2005 May;25(3):261-309. Review.

PMID:
15717297
[PubMed - indexed for MEDLINE]
13.

Histone H4 lysine 16 acetylation regulates cellular lifespan.

Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL.

Nature. 2009 Jun 11;459(7248):802-7. doi: 10.1038/nature08085.

PMID:
19516333
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Histone deacetylase-dependent establishment and maintenance of broad low-level histone acetylation within a tissue-specific chromatin domain.

Im H, Grass JA, Christensen HM, Perkins A, Bresnick EH.

Biochemistry. 2002 Dec 24;41(51):15152-60.

PMID:
12484752
[PubMed - indexed for MEDLINE]
15.

Regulation of histone modifying enzymes by the ubiquitin-proteasome system.

Zou C, Mallampalli RK.

Biochim Biophys Acta. 2014 Apr;1843(4):694-702. doi: 10.1016/j.bbamcr.2013.12.016. Epub 2014 Jan 3. Review.

PMID:
24389248
[PubMed - indexed for MEDLINE]
16.

Inhibitors of NAD+ dependent histone deacetylases (sirtuins).

Neugebauer RC, Sippl W, Jung M.

Curr Pharm Des. 2008;14(6):562-73. Review.

PMID:
18336301
[PubMed - indexed for MEDLINE]
17.

Protein deacetylases: enzymes with functional diversity as novel therapeutic targets.

Yoshida M, Shimazu T, Matsuyama A.

Prog Cell Cycle Res. 2003;5:269-78. Review.

PMID:
14593721
[PubMed - indexed for MEDLINE]
18.

Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism.

Fang S, Miao J, Xiang L, Ponugoti B, Treuter E, Kemper JK.

Mol Cell Biol. 2007 Feb;27(4):1407-24. Epub 2006 Dec 4.

PMID:
17145766
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors.

King ON, Li XS, Sakurai M, Kawamura A, Rose NR, Ng SS, Quinn AM, Rai G, Mott BT, Beswick P, Klose RJ, Oppermann U, Jadhav A, Heightman TD, Maloney DJ, Schofield CJ, Simeonov A.

PLoS One. 2010 Nov 23;5(11):e15535. doi: 10.1371/journal.pone.0015535.

PMID:
21124847
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Histone deacetylase inhibitors target diabetes via chromatin remodeling or as chemical chaperones?

Lawless MW, O'Byrne KJ, Gray SG.

Curr Diabetes Rev. 2009 Aug;5(3):201-9. Review.

PMID:
19689255
[PubMed - indexed for MEDLINE]

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