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Results: 1 to 20 of 79

1.

Gadd45 in stress signaling.

Liebermann DA, Hoffman B.

J Mol Signal. 2008 Sep 12;3:15. doi: 10.1186/1750-2187-3-15.

PMID:
18789159
[PubMed]
Free PMC Article
2.

Stress sensor Gadd45 genes as therapeutic targets in cancer.

Cretu A, Sha X, Tront J, Hoffman B, Liebermann DA.

Cancer Ther. 2009;7(A):268-276.

PMID:
19652693
[PubMed]
Free PMC Article
3.

Gadd45 in the response of hematopoietic cells to genotoxic stress.

Liebermann DA, Hoffman B.

Blood Cells Mol Dis. 2007 Nov-Dec;39(3):329-35. Epub 2007 Jul 30. Review.

PMID:
17659913
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Gadd45 stress sensors in malignancy and leukemia.

Liebermann DA, Tront JS, Sha X, Mukherjee K, Mohamed-Hadley A, Hoffman B.

Crit Rev Oncog. 2011;16(1-2):129-40. Review.

PMID:
22150313
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Ectopic expression of MyD118/Gadd45/CR6 (Gadd45beta/alpha/gamma) sensitizes neoplastic cells to genotoxic stress-induced apoptosis.

Zhang W, Hoffman B, Liebermann DA.

Int J Oncol. 2001 Apr;18(4):749-57.

PMID:
11251170
[PubMed - indexed for MEDLINE]
6.

The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1.

Vairapandi M, Balliet AG, Fornace AJ Jr, Hoffman B, Liebermann DA.

Oncogene. 1996 Jun 20;12(12):2579-94.

PMID:
8700517
[PubMed - indexed for MEDLINE]
7.

Role of Gadd45 in apoptosis.

Sheikh MS, Hollander MC, Fornance AJ Jr.

Biochem Pharmacol. 2000 Jan 1;59(1):43-5. Review.

PMID:
10605933
[PubMed - indexed for MEDLINE]
8.

The central region of Gadd45 is required for its interaction with p21/WAF1.

Zhao H, Jin S, Antinore MJ, Lung FD, Fan F, Blanck P, Roller P, Fornace AJ Jr, Zhan Q.

Exp Cell Res. 2000 Jul 10;258(1):92-100.

PMID:
10912791
[PubMed - indexed for MEDLINE]
9.

Identification of a functional domain in a GADD45-mediated G2/M checkpoint.

Yang Q, Manicone A, Coursen JD, Linke SP, Nagashima M, Forgues M, Wang XW.

J Biol Chem. 2000 Nov 24;275(47):36892-8.

PMID:
10973963
[PubMed - indexed for MEDLINE]
Free Article
10.

Involvement of the MAP kinase pathways in induction of GADD45 following UV radiation.

Tong T, Fan W, Zhao H, Jin S, Fan F, Blanck P, Alomo I, Rajasekaran B, Liu Y, Holbrook NJ, Zhan Q.

Exp Cell Res. 2001 Sep 10;269(1):64-72.

PMID:
11525640
[PubMed - indexed for MEDLINE]
11.

Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells.

Hoffman B, Liebermann DA.

J Cell Physiol. 2009 Jan;218(1):26-31. doi: 10.1002/jcp.21582. Review.

PMID:
18780287
[PubMed - indexed for MEDLINE]
12.

Stress-induced JNK activation is independent of Gadd45 induction.

Shaulian E, Karin M.

J Biol Chem. 1999 Oct 15;274(42):29595-8.

PMID:
10514425
[PubMed - indexed for MEDLINE]
Free Article
13.

gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress.

Wang X, Gorospe M, Holbrook NJ.

J Biol Chem. 1999 Oct 15;274(42):29599-602.

PMID:
10514426
[PubMed - indexed for MEDLINE]
Free Article
14.

GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress.

Vairapandi M, Balliet AG, Hoffman B, Liebermann DA.

J Cell Physiol. 2002 Sep;192(3):327-38.

PMID:
12124778
[PubMed - indexed for MEDLINE]
15.

The GADD45 inhibition of Cdc2 kinase correlates with GADD45-mediated growth suppression.

Jin S, Antinore MJ, Lung FD, Dong X, Zhao H, Fan F, Colchagie AB, Blanck P, Roller PP, Fornace AJ Jr, Zhan Q.

J Biol Chem. 2000 Jun 2;275(22):16602-8.

PMID:
10747892
[PubMed - indexed for MEDLINE]
Free Article
16.

DNA damage inducible-gene expression following platinum treatment in human ovarian carcinoma cell lines.

Delmastro DA, Li J, Vaisman A, Solle M, Chaney SG.

Cancer Chemother Pharmacol. 1997;39(3):245-53.

PMID:
8996528
[PubMed - indexed for MEDLINE]
17.

Loss of p21WAF1/Cip1 in Gadd45-deficient keratinocytes restores DNA repair capacity.

Maeda T, Espino RA, Chomey EG, Luong L, Bano A, Meakins D, Tron VA.

Carcinogenesis. 2005 Oct;26(10):1804-10. Epub 2005 May 25.

PMID:
15917306
[PubMed - indexed for MEDLINE]
Free Article
18.

Gadd45-alpha and Gadd45-gamma utilize p38 and JNK signaling pathways to induce cell cycle G2/M arrest in Hep-G2 hepatoma cells.

Zhu N, Shao Y, Xu L, Yu L, Sun L.

Mol Biol Rep. 2009 Nov;36(8):2075-85. doi: 10.1007/s11033-008-9419-9. Epub 2008 Dec 2.

PMID:
19048389
[PubMed - indexed for MEDLINE]
19.

Gadd45a suppresses Ras-driven mammary tumorigenesis by activation of c-Jun NH2-terminal kinase and p38 stress signaling resulting in apoptosis and senescence.

Tront JS, Hoffman B, Liebermann DA.

Cancer Res. 2006 Sep 1;66(17):8448-54. Erratum in: Cancer Res. 2007 Jan 1;67(1):427.

PMID:
16951155
[PubMed - indexed for MEDLINE]
Free Article
20.

Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth control.

Vairapandi M, Azam N, Balliet AG, Hoffman B, Liebermann DA.

J Biol Chem. 2000 Jun 2;275(22):16810-9.

PMID:
10828065
[PubMed - indexed for MEDLINE]
Free Article

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