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Results: 1 to 20 of 88

1.

15-lipoxygenase-1 activates tumor suppressor p53 independent of enzymatic activity.

Zhu H, Glasgow W, George MD, Chrysovergis K, Olden K, Roberts JD, Eling T.

Int J Cancer. 2008 Dec 15;123(12):2741-9. doi: 10.1002/ijc.23855.

PMID:
18785202
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Overexpression of 15-lipoxygenase-1 induces growth arrest through phosphorylation of p53 in human colorectal cancer cells.

Kim JS, Baek SJ, Bottone FG Jr, Sali T, Eling TE.

Mol Cancer Res. 2005 Sep;3(9):511-7.

PMID:
16179498
[PubMed - indexed for MEDLINE]
Free Article
3.

Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.

Zerbini LF, Wang Y, Correa RG, Cho JY, Libermann TA.

Cell Cycle. 2005 Sep;4(9):1247-53. Epub 2005 Sep 24.

PMID:
16082226
[PubMed - indexed for MEDLINE]
Free Article
4.

Distinct effects of annexin A7 and p53 on arachidonate lipoxygenation in prostate cancer cells involve 5-lipoxygenase transcription.

Torosyan Y, Dobi A, Naga S, Mezhevaya K, Glasman M, Norris C, Jiang G, Mueller G, Pollard H, Srivastava M.

Cancer Res. 2006 Oct 1;66(19):9609-16.

PMID:
17018618
[PubMed - indexed for MEDLINE]
Free Article
5.

15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells.

Shureiqi I, Chen D, Lee JJ, Yang P, Newman RA, Brenner DE, Lotan R, Fischer SM, Lippman SM.

J Natl Cancer Inst. 2000 Jul 19;92(14):1136-42.

PMID:
10904086
[PubMed - indexed for MEDLINE]
Free Article
6.

The 15-lipoxygenase-1 expression may enhance the sensitivity to non-steroidal anti-inflammatory drug-induced apoptosis in colorectal cancers from patients who are treated with the compounds.

Yoshinaga M, Murao H, Kitamura Y, Koga K, Tsuruta S, Igarashi H, Nakamura K, Takayanagi R.

J Gastroenterol Hepatol. 2007 Dec;22(12):2324-9. Epub 2007 Jun 7.

PMID:
17559385
[PubMed - indexed for MEDLINE]
7.

Acetylation by histone acetyltransferase CREB-binding protein/p300 of STAT6 is required for transcriptional activation of the 15-lipoxygenase-1 gene.

Shankaranarayanan P, Chaitidis P, Kühn H, Nigam S.

J Biol Chem. 2001 Nov 16;276(46):42753-60. Epub 2001 Aug 16.

PMID:
11509556
[PubMed - indexed for MEDLINE]
Free Article
8.

SN2 DNA-alkylating agent-induced phosphorylation of p53 and activation of p21 gene expression.

Jaiswal AS, Narayan S.

Mutat Res. 2002 Mar 20;500(1-2):17-30.

PMID:
11890931
[PubMed - indexed for MEDLINE]
9.

2-Chloroethyl-3-sarcosinamide-1-nitrosourea (SarCNU) exhibits p53-dependent and -independent antiproliferative activity in human nasopharyngeal carcinoma cells in vitro and in vivo.

Nguyen TH, Ong CK, Wong E, Leong CT, Panasci L, Huynh H.

Int J Oncol. 2005 Oct;27(4):1131-40.

PMID:
16142332
[PubMed - indexed for MEDLINE]
10.

15-LOX-1 inhibits p21 (Cip/WAF 1) expression by enhancing MEK-ERK 1/2 signaling in colon carcinoma cells.

Yoshinaga M, Buchanan FG, DuBois RN.

Prostaglandins Other Lipid Mediat. 2004 Jan;73(1-2):111-22.

PMID:
15165036
[PubMed - indexed for MEDLINE]
11.

Function of polo-like kinase 3 in NF-kappaB-mediated proapoptotic response.

Li Z, Niu J, Uwagawa T, Peng B, Chiao PJ.

J Biol Chem. 2005 Apr 29;280(17):16843-50. Epub 2005 Jan 25.

PMID:
15671037
[PubMed - indexed for MEDLINE]
Free Article
12.

Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells.

Kuo PC, Liu HF, Chao JI.

J Biol Chem. 2004 Dec 31;279(53):55875-85. Epub 2004 Sep 29.

PMID:
15456784
[PubMed - indexed for MEDLINE]
Free Article
13.

Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells.

Zhang H, Shi X, Zhang QJ, Hampong M, Paddon H, Wahyuningsih D, Pelech S.

J Biol Chem. 2002 Nov 15;277(46):43648-58. Epub 2002 Sep 6.

PMID:
12221076
[PubMed - indexed for MEDLINE]
Free Article
14.

Involvement of the multiple tumor suppressor genes and 12-lipoxygenase in human prostate cancer. Therapeutic implications.

Gao X, Porter AT, Honn KV.

Adv Exp Med Biol. 1997;407:41-53. Review.

PMID:
9321930
[PubMed - indexed for MEDLINE]
15.

Mutant human tumor suppressor p53 modulates the activation of mitogen-activated protein kinase and nuclear factor-kappaB, but not c-Jun N-terminal kinase and activated protein-1.

Gulati AP, Yang YM, Harter D, Mukhopadhyay A, Aggarwal BB, Benzil DL, Whysner J, Albino AP, Murali R, Jhanwar-Uniyal M.

Mol Carcinog. 2006 Jan;45(1):26-37. Erratum in: Mol Carcinog. 2006 Jul;45(7):549. Aggarwal, Bharat A [corrected to Aggarwal, Bharat B].

PMID:
16267831
[PubMed - indexed for MEDLINE]
16.

Hypersensitivity to chromium-induced DNA damage correlates with constitutive deregulation of upstream p53 kinases in p21-/- HCT116 colon cancer cells.

Hill R, Leidal AM, Madureira PA, Gillis LD, Cochrane HK, Waisman DM, Chiu A, Lee PW.

DNA Repair (Amst). 2008 Feb 1;7(2):239-52. Epub 2007 Nov 19.

PMID:
18024214
[PubMed - indexed for MEDLINE]
17.

Activation of protein kinase G up-regulates expression of 15-lipoxygenase-1 in human colon cancer cells.

Deguchi A, Xing SW, Shureiqi I, Yang P, Newman RA, Lippman SM, Feinmark SJ, Oehlen B, Weinstein IB.

Cancer Res. 2005 Sep 15;65(18):8442-7.

PMID:
16166323
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

Opposing effects of 15-lipoxygenase-1 and -2 metabolites on MAPK signaling in prostate. Alteration in peroxisome proliferator-activated receptor gamma.

Hsi LC, Wilson LC, Eling TE.

J Biol Chem. 2002 Oct 25;277(43):40549-56. Epub 2002 Aug 19.

PMID:
12189136
[PubMed - indexed for MEDLINE]
Free Article
20.

Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression.

Bon G, Di Carlo SE, Folgiero V, Avetrani P, Lazzari C, D'Orazi G, Brizzi MF, Sacchi A, Soddu S, Blandino G, Mottolese M, Falcioni R.

Cancer Res. 2009 Jul 15;69(14):5978-86. doi: 10.1158/0008-5472.CAN-09-0244. Epub 2009 Jun 30.

PMID:
19567674
[PubMed - indexed for MEDLINE]
Free Article
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