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Results: 1 to 20 of 184

1.

Hypoxia inducible factor-1alpha inactivation unveils a link between tumor cell metabolism and hypoxia-induced cell death.

Favaro E, Nardo G, Persano L, Masiero M, Moserle L, Zamarchi R, Rossi E, Esposito G, Plebani M, Sattler U, Mann T, Mueller-Klieser W, Ciminale V, Amadori A, Indraccolo S.

Am J Pathol. 2008 Oct;173(4):1186-201. doi: 10.2353/ajpath.2008.071183. Epub 2008 Sep 4.

PMID:
18772337
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha.

Huang L, Ao Q, Zhang Q, Yang X, Xing H, Li F, Chen G, Zhou J, Wang S, Xu G, Meng L, Lu Y, Ma D.

J Cancer Res Clin Oncol. 2010 Mar;136(3):447-56. doi: 10.1007/s00432-009-0675-4. Epub 2009 Sep 16.

PMID:
19760195
[PubMed - indexed for MEDLINE]
3.

Potent inhibition of tumoral hypoxia-inducible factor 1alpha by albendazole.

Pourgholami MH, Cai ZY, Badar S, Wangoo K, Poruchynsky MS, Morris DL.

BMC Cancer. 2010 Apr 15;10:143. doi: 10.1186/1471-2407-10-143.

PMID:
20398289
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Nuclear factor-κB2/p100 promotes endometrial carcinoma cell survival under hypoxia in a HIF-1α independent manner.

Yeramian A, Santacana M, Sorolla A, Llobet D, Encinas M, Velasco A, Bahi N, Eritja N, Domingo M, Oliva E, Dolcet X, Matias-Guiu X.

Lab Invest. 2011 Jun;91(6):859-71. doi: 10.1038/labinvest.2011.58. Epub 2011 May 2.

PMID:
21537326
[PubMed - indexed for MEDLINE]
Free Article
5.

[Impact of RNA interference targeting hypoxia-inducible factor-1alpha on chemosensitivity in esophageal squamous cell carcinoma cells under hypoxia].

Wu XA, Sun Y, Fan QX, Wang LX, Wang RL, Zhang L.

Zhonghua Yi Xue Za Zhi. 2007 Oct 9;87(37):2640-4. Chinese.

PMID:
18162154
[PubMed - indexed for MEDLINE]
6.

[Effect of hypoxia on the chemotherapeutic sensitivity of human ovarian cancer cells to paclitaxel and its mechanism].

Huang L, Zhang QH, Ao QL, Xing H, Lu YP, Ma D.

Zhonghua Zhong Liu Za Zhi. 2007 Feb;29(2):96-100. Chinese.

PMID:
17645840
[PubMed - indexed for MEDLINE]
7.

Hypoxia-inducible factor-1alpha promotes nonhypoxia-mediated proliferation in colon cancer cells and xenografts.

Dang DT, Chen F, Gardner LB, Cummins JM, Rago C, Bunz F, Kantsevoy SV, Dang LH.

Cancer Res. 2006 Feb 1;66(3):1684-936.

PMID:
16452228
[PubMed - indexed for MEDLINE]
Free Article
9.

Hypoxia-inducible transcription factor-1alpha promotes hypoxia-induced A549 apoptosis via a mechanism that involves the glycolysis pathway.

Luo F, Liu X, Yan N, Li S, Cao G, Cheng Q, Xia Q, Wang H.

BMC Cancer. 2006 Jan 27;6:26.

PMID:
16438736
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms.

Marín-Hernández A, Gallardo-Pérez JC, Ralph SJ, Rodríguez-Enríquez S, Moreno-Sánchez R.

Mini Rev Med Chem. 2009 Aug;9(9):1084-101. Review.

PMID:
19689405
[PubMed - indexed for MEDLINE]
11.

Activation of hypoxia-inducible factor-1alpha is necessary for lysophosphatidic acid-induced vascular endothelial growth factor expression.

Lee J, Park SY, Lee EK, Park CG, Chung HC, Rha SY, Kim YK, Bae GU, Kim BK, Han JW, Lee HY.

Clin Cancer Res. 2006 Nov 1;12(21):6351-8.

PMID:
17085645
[PubMed - indexed for MEDLINE]
Free Article
12.

[Effect of silencing HIF-1alpha by RNA interference on expression of vascular endothelial growth factor in osteosarcoma cell line SaOS-2 under hypoxia].

Wu Q, Yang SH, Wang RY, Ye SN, Xia T, Ma DZ.

Ai Zheng. 2005 May;24(5):531-5. Chinese.

PMID:
15890092
[PubMed - indexed for MEDLINE]
13.

An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells.

Lau CK, Yang ZF, Ho DW, Ng MN, Yeoh GC, Poon RT, Fan ST.

Clin Cancer Res. 2009 May 15;15(10):3462-71. doi: 10.1158/1078-0432.CCR-08-2127. Epub 2009 May 15.

PMID:
19447872
[PubMed - indexed for MEDLINE]
Free Article
14.

Constitutive activation of hypoxia-inducible genes related to overexpression of hypoxia-inducible factor-1alpha in clear cell renal carcinomas.

Wiesener MS, Münchenhagen PM, Berger I, Morgan NV, Roigas J, Schwiertz A, Jürgensen JS, Gruber G, Maxwell PH, Löning SA, Frei U, Maher ER, Gröne HJ, Eckardt KU.

Cancer Res. 2001 Jul 1;61(13):5215-22.

PMID:
11431362
[PubMed - indexed for MEDLINE]
Free Article
15.

Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha.

Zhang X, Kon T, Wang H, Li F, Huang Q, Rabbani ZN, Kirkpatrick JP, Vujaskovic Z, Dewhirst MW, Li CY.

Cancer Res. 2004 Nov 15;64(22):8139-42.

PMID:
15548675
[PubMed - indexed for MEDLINE]
Free Article
16.

Silencing hypoxia-inducible factor-1alpha inhibits cell migration and invasion under hypoxic environment in malignant gliomas.

Fujiwara S, Nakagawa K, Harada H, Nagato S, Furukawa K, Teraoka M, Seno T, Oka K, Iwata S, Ohnishi T.

Int J Oncol. 2007 Apr;30(4):793-802.

PMID:
17332917
[PubMed - indexed for MEDLINE]
17.

Treatment with siRNA and antisense oligonucleotides targeted to HIF-1alpha induced apoptosis in human tongue squamous cell carcinomas.

Zhang Q, Zhang ZF, Rao JY, Sato JD, Brown J, Messadi DV, Le AD.

Int J Cancer. 2004 Oct 10;111(6):849-57.

PMID:
15300796
[PubMed - indexed for MEDLINE]
18.

[Hypoxia increases the expression of heparitinase and the invasiveness through the hypoxia inducible factor-1alpha dependent pathway in human ovarian cancer cell line SKOV3].

Yuan CX, Gu S, Zhang SH, Zhang XN.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2008 Dec;30(6):711-6. Chinese.

PMID:
19180921
[PubMed - indexed for MEDLINE]
Free Article
19.

Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer.

Baker AF, Koh MY, Williams RR, James B, Wang H, Tate WR, Gallegos A, Von Hoff DD, Han H, Powis G.

Pancreas. 2008 Mar;36(2):178-86. doi: 10.1097/MPA.0b013e31815929fe.

PMID:
18376310
[PubMed - indexed for MEDLINE]
20.

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