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Results: 1 to 20 of 157

1.

Genetic dissection of the role of catechol-O-methyltransferase in cognition and stress reactivity in mice.

Papaleo F, Crawley JN, Song J, Lipska BK, Pickel J, Weinberger DR, Chen J.

J Neurosci. 2008 Aug 27;28(35):8709-23. doi: 10.1523/JNEUROSCI.2077-08.2008.

PMID:
18753372
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Phenotypic characterization of cognition and social behavior in mice with heterozygous versus homozygous deletion of catechol-O-methyltransferase.

Babovic D, O'Tuathaigh CM, O'Connor AM, O'Sullivan GJ, Tighe O, Croke DT, Karayiorgou M, Gogos JA, Cotter D, Waddington JL.

Neuroscience. 2008 Sep 9;155(4):1021-9. doi: 10.1016/j.neuroscience.2008.07.006. Epub 2008 Jul 10.

PMID:
18674597
[PubMed - indexed for MEDLINE]
3.

Startle reactivity and prepulse inhibition of the acoustic startle response are modulated by catechol-O-methyl-transferase Val(158) Met polymorphism in adults with 22q11 deletion syndrome.

de Koning MB, Boot E, Bloemen OJ, van Duin ED, Abel KM, de Haan L, Linszen DH, van Amelsvoort TA.

J Psychopharmacol. 2012 Dec;26(12):1548-60. doi: 10.1177/0269881112456610. Epub 2012 Sep 5.

PMID:
22952320
[PubMed - indexed for MEDLINE]
4.

Improvement of prepulse inhibition and executive function by the COMT inhibitor tolcapone depends on COMT Val158Met polymorphism.

Giakoumaki SG, Roussos P, Bitsios P.

Neuropsychopharmacology. 2008 Dec;33(13):3058-68. doi: 10.1038/npp.2008.82. Epub 2008 Jun 4.

PMID:
18536698
[PubMed - indexed for MEDLINE]
Free Article
5.

Nicotine normalizes event related potentials in COMT-Val-tg mice and increases gamma and theta spectral density.

Cao YA, Featherstone RE, Gandal MJ, Liang Y, Jutzeler C, Saunders J, Tatard-Leitman V, Chen J, Weinberger DR, Lerman C, Siegel SJ.

Behav Neurosci. 2012 Apr;126(2):332-43. doi: 10.1037/a0027047. Epub 2012 Feb 6.

PMID:
22309446
[PubMed - indexed for MEDLINE]
6.

Prepulse inhibition of the startle reflex depends on the catechol O-methyltransferase Val158Met gene polymorphism.

Roussos P, Giakoumaki SG, Rogdaki M, Pavlakis S, Frangou S, Bitsios P.

Psychol Med. 2008 Nov;38(11):1651-8. doi: 10.1017/S0033291708002912. Epub 2008 Feb 8.

PMID:
18261249
[PubMed - indexed for MEDLINE]
7.

The flexible mind is associated with the catechol-O-methyltransferase (COMT) Val158Met polymorphism: evidence for a role of dopamine in the control of task-switching.

Colzato LS, Waszak F, Nieuwenhuis S, Posthuma D, Hommel B.

Neuropsychologia. 2010 Jul;48(9):2764-8. doi: 10.1016/j.neuropsychologia.2010.04.023. Epub 2010 Apr 29.

PMID:
20434465
[PubMed - indexed for MEDLINE]
8.

Stress-related methylation of the catechol-O-methyltransferase Val 158 allele predicts human prefrontal cognition and activity.

Ursini G, Bollati V, Fazio L, Porcelli A, Iacovelli L, Catalani A, Sinibaldi L, Gelao B, Romano R, Rampino A, Taurisano P, Mancini M, Di Giorgio A, Popolizio T, Baccarelli A, De Blasi A, Blasi G, Bertolino A.

J Neurosci. 2011 May 4;31(18):6692-8. doi: 10.1523/JNEUROSCI.6631-10.2011.

PMID:
21543598
[PubMed - indexed for MEDLINE]
Free Article
9.

The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks.

Heinz A, Smolka MN.

Rev Neurosci. 2006;17(3):359-67. Review.

PMID:
16878403
[PubMed - indexed for MEDLINE]
10.

Effect of S-COMT deficiency on behavior and extracellular brain dopamine concentrations in mice.

Tammimäki A, Käenmäki M, Kambur O, Kulesskaya N, Keisala T, Karvonen E, García-Horsman JA, Rauvala H, Männistö PT.

Psychopharmacology (Berl). 2010 Sep;211(4):389-401. doi: 10.1007/s00213-010-1944-2. Epub 2010 Jul 9.

PMID:
20617305
[PubMed - indexed for MEDLINE]
11.

Effects of sex and COMT genotype on environmentally modulated cognitive control in mice.

Papaleo F, Erickson L, Liu G, Chen J, Weinberger DR.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20160-5. doi: 10.1073/pnas.1214397109. Epub 2012 Nov 19.

PMID:
23169629
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Stress-induced analgesia and morphine responses are changed in catechol-O-methyltransferase-deficient male mice.

Kambur O, Männistö PT, Viljakka K, Reenilä I, Lemberg K, Kontinen VK, Karayiorgou M, Gogos JA, Kalso E.

Basic Clin Pharmacol Toxicol. 2008 Oct;103(4):367-73. doi: 10.1111/j.1742-7843.2008.00289.x.

PMID:
18834357
[PubMed - indexed for MEDLINE]
13.

Variations in the catechol O-methyltransferase polymorphism and prefrontally guided behaviors in adolescents.

Wahlstrom D, White T, Hooper CJ, Vrshek-Schallhorn S, Oetting WS, Brott MJ, Luciana M.

Biol Psychiatry. 2007 Mar 1;61(5):626-32. Epub 2006 Oct 2.

PMID:
17014828
[PubMed - indexed for MEDLINE]
14.

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.

Chen J, Lipska BK, Halim N, Ma QD, Matsumoto M, Melhem S, Kolachana BS, Hyde TM, Herman MM, Apud J, Egan MF, Kleinman JE, Weinberger DR.

Am J Hum Genet. 2004 Nov;75(5):807-21. Epub 2004 Sep 27. Erratum in: Am J Hum Genet. 2005 Jun;76(6):1089.

PMID:
15457404
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine/D2 pathways.

Papaleo F, Yang F, Garcia S, Chen J, Lu B, Crawley JN, Weinberger DR.

Mol Psychiatry. 2012 Jan;17(1):85-98. doi: 10.1038/mp.2010.106. Epub 2010 Oct 19.

PMID:
20956979
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The COMT Val158Met polymorphism modulates working memory performance under acute stress.

Buckert M, Kudielka BM, Reuter M, Fiebach CJ.

Psychoneuroendocrinology. 2012 Nov;37(11):1810-21. doi: 10.1016/j.psyneuen.2012.03.014. Epub 2012 Apr 14.

PMID:
22503421
[PubMed - indexed for MEDLINE]
17.

Treatment of cognitive deficits associated with schizophrenia: potential role of catechol-O-methyltransferase inhibitors.

Apud JA, Weinberger DR.

CNS Drugs. 2007;21(7):535-57. Review.

PMID:
17579498
[PubMed - indexed for MEDLINE]
18.

Catechol-O-methyltransferase polymorphisms and some implications for cognitive therapeutics.

Diaz-Asper CM, Weinberger DR, Goldberg TE.

NeuroRx. 2006 Jan;3(1):97-105. Review.

PMID:
16490416
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Aberrant calcium/calmodulin-dependent protein kinase II (CaMKII) activity is associated with abnormal dendritic spine morphology in the ATRX mutant mouse brain.

Shioda N, Beppu H, Fukuda T, Li E, Kitajima I, Fukunaga K.

J Neurosci. 2011 Jan 5;31(1):346-58. doi: 10.1523/JNEUROSCI.4816-10.2011.

PMID:
21209221
[PubMed - indexed for MEDLINE]
Free Article
20.

Catechol-o-methyltransferase enzyme activity and protein expression in human prefrontal cortex across the postnatal lifespan.

Tunbridge EM, Weickert CS, Kleinman JE, Herman MM, Chen J, Kolachana BS, Harrison PJ, Weinberger DR.

Cereb Cortex. 2007 May;17(5):1206-12. Epub 2006 Jul 11.

PMID:
16835293
[PubMed - indexed for MEDLINE]
Free Article

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