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Results: 1 to 20 of 293

1.

Increased KIT signalling with up-regulation of cyclin D correlates to accelerated proliferation and shorter disease-free survival in gastrointestinal stromal tumours (GISTs) with KIT exon 11 deletions.

Haller F, Löbke C, Ruschhaupt M, Schulten HJ, Schwager S, Gunawan B, Armbrust T, Langer C, Ramadori G, Sültmann H, Poustka A, Korf U, Füzesi L.

J Pathol. 2008 Oct;216(2):225-35. doi: 10.1002/path.2402.

PMID:
18729075
[PubMed - indexed for MEDLINE]
2.

Loss of 9p leads to p16INK4A down-regulation and enables RB/E2F1-dependent cell cycle promotion in gastrointestinal stromal tumours (GISTs).

Haller F, Löbke C, Ruschhaupt M, Cameron S, Schulten HJ, Schwager S, von Heydebreck A, Gunawan B, Langer C, Ramadori G, Sültmann H, Poustka A, Korf U, Füzesi L.

J Pathol. 2008 Jul;215(3):253-62. doi: 10.1002/path.2352.

PMID:
18438954
[PubMed - indexed for MEDLINE]
3.

Site-dependent differential KIT and PDGFRA expression in gastric and intestinal gastrointestinal stromal tumors.

Haller F, Happel N, Schulten HJ, von Heydebreck A, Schwager S, Armbrust T, Langer C, Gunawan B, Doenecke D, Füzesi L.

Mod Pathol. 2007 Oct;20(10):1103-11. Epub 2007 Aug 3.

PMID:
17673922
[PubMed - indexed for MEDLINE]
Free Article
4.

Epithelioid/mixed phenotype in gastrointestinal stromal tumors with KIT mutation from the stomach is associated with accelerated passage of late phases of the cell cycle and shorter disease-free survival.

Haller F, Cortis J, Helfrich J, Cameron S, Schüler P, Schwager S, Gunawan B, Füzesi L, Agaimy A.

Mod Pathol. 2011 Feb;24(2):248-55. doi: 10.1038/modpathol.2010.188. Epub 2010 Sep 10.

PMID:
20834236
[PubMed - indexed for MEDLINE]
Free Article
5.

Multiple sporadic gastrointestinal stromal tumors (GISTs) of the proximal stomach are caused by different somatic KIT mutations suggesting a field effect.

Agaimy A, Dirnhofer S, Wünsch PH, Terracciano LM, Tornillo L, Bihl MP.

Am J Surg Pathol. 2008 Oct;32(10):1553-9. doi: 10.1097/PAS.0b013e31817587ea.

PMID:
18724245
[PubMed - indexed for MEDLINE]
6.

KIT and PDGFRalpha mutations in 104 patients with gastrointestinal stromal tumors (GISTs): a population-based study.

Braconi C, Bracci R, Bearzi I, Bianchi F, Costagliola A, Catalani R, Mandolesi A, Ranaldi R, Galizia E, Cascinu S, Rossi G, Giustini L, Latini L, Valeri N, Cellerino R.

Ann Oncol. 2008 Apr;19(4):706-10. doi: 10.1093/annonc/mdm503. Epub 2008 Jan 10.

PMID:
18187489
[PubMed - indexed for MEDLINE]
Free Article
7.

Prognostic role of E2F1 and members of the CDKN2A network in gastrointestinal stromal tumors.

Haller F, Gunawan B, von Heydebreck A, Schwager S, Schulten HJ, Wolf-Salgó J, Langer C, Ramadori G, Sültmann H, Füzesi L.

Clin Cancer Res. 2005 Sep 15;11(18):6589-97.

PMID:
16166437
[PubMed - indexed for MEDLINE]
Free Article
8.

Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases.

Lasota J, Corless CL, Heinrich MC, Debiec-Rychter M, Sciot R, Wardelmann E, Merkelbach-Bruse S, Schildhaus HU, Steigen SE, Stachura J, Wozniak A, Antonescu C, Daum O, Martin J, Del Muro JG, Miettinen M.

Mod Pathol. 2008 Apr;21(4):476-84. doi: 10.1038/modpathol.2008.2. Epub 2008 Feb 1.

PMID:
18246046
[PubMed - indexed for MEDLINE]
Free Article
9.

Gastrointestinal stromal tumours (GISTs): a clinicopathological and molecular study of 66 cases.

Koay MH, Goh YW, Iacopetta B, Grieu F, Segal A, Sterrett GF, Platten M, Spagnolo DV.

Pathology. 2005 Feb;37(1):22-31.

PMID:
15875730
[PubMed - indexed for MEDLINE]
10.

Expression profiling of GIST: CD133 is associated with KIT exon 11 mutations, gastric location and poor prognosis.

Arne G, Kristiansson E, Nerman O, Kindblom LG, Ahlman H, Nilsson B, Nilsson O.

Int J Cancer. 2011 Sep 1;129(5):1149-61. doi: 10.1002/ijc.25755. Epub 2011 Jan 7.

PMID:
21064103
[PubMed - indexed for MEDLINE]
11.

Deletion of the KIT gene is associated with liver metastasis and poor prognosis in patients with gastrointestinal stromal tumor in the stomach.

Cho S, Kitadai Y, Yoshida S, Tanaka S, Yoshihara M, Yoshida K, Chayama K.

Int J Oncol. 2006 Jun;28(6):1361-7.

PMID:
16685437
[PubMed - indexed for MEDLINE]
12.

Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors.

Singer S, Rubin BP, Lux ML, Chen CJ, Demetri GD, Fletcher CD, Fletcher JA.

J Clin Oncol. 2002 Sep 15;20(18):3898-905.

PMID:
12228211
[PubMed - indexed for MEDLINE]
13.

Genetic and pathologic characteristics of gastrointestinal stromal tumors in extragastric lesions.

Cho S, Kitadai Y, Yoshida S, Tanaka S, Yoshihara M, Yoshida K, Chayama K.

Int J Mol Med. 2006 Dec;18(6):1067-71.

PMID:
17089009
[PubMed - indexed for MEDLINE]
14.

The location of KIT and PDGFRA gene mutations in gastrointestinal stromal tumours is site and phenotype associated.

Penzel R, Aulmann S, Moock M, Schwarzbach M, Rieker RJ, Mechtersheimer G.

J Clin Pathol. 2005 Jun;58(6):634-9.

PMID:
15917417
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Gastrointestinal stromal tumors presenting as omental masses--a clinicopathologic analysis of 95 cases.

Miettinen M, Sobin LH, Lasota J.

Am J Surg Pathol. 2009 Sep;33(9):1267-75. doi: 10.1097/PAS.0b013e3181a13e99.

PMID:
19440146
[PubMed - indexed for MEDLINE]
16.

[Therapeutic targets in gastrointestinal stromal tumors].

Wardelmann E, Schildhaus HU, Merkelbach-Bruse S, Büttner R.

Verh Dtsch Ges Pathol. 2006;90:73-9. German.

PMID:
17867582
[PubMed - indexed for MEDLINE]
17.

Analysis of mutation and expression of c-kit and PDGFR-alpha gene in gastrointestinal stromal tumor.

Zheng S, Chen LR, Wang HJ, Chen SZ.

Hepatogastroenterology. 2007 Dec;54(80):2285-90.

PMID:
18265649
[PubMed - indexed for MEDLINE]
18.

MicroRNA-494 downregulates KIT and inhibits gastrointestinal stromal tumor cell proliferation.

Kim WK, Park M, Kim YK, Tae YK, Yang HK, Lee JM, Kim H.

Clin Cancer Res. 2011 Dec 15;17(24):7584-94. doi: 10.1158/1078-0432.CCR-11-0166. Epub 2011 Oct 31.

PMID:
22042971
[PubMed - indexed for MEDLINE]
Free Article
19.

Altered expression of cell cycle regulatory proteins in gastrointestinal stromal tumors: markers with potential prognostic implications.

Sabah M, Cummins R, Leader M, Kay E.

Hum Pathol. 2006 Jun;37(6):648-55.

PMID:
16733203
[PubMed - indexed for MEDLINE]
20.

KIT exon 11 codon 557/558 deletion/insertion mutations define a subset of gastrointestinal stromal tumors with malignant potential.

Kontogianni-Katsarou K, Dimitriadis E, Lariou C, Kairi-Vassilatou E, Pandis N, Kondi-Paphiti A.

World J Gastroenterol. 2008 Mar 28;14(12):1891-7.

PMID:
18350628
[PubMed - indexed for MEDLINE]
Free PMC Article

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