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Results: 1 to 20 of 293

1.

Fibulin-5 initiates epithelial-mesenchymal transition (EMT) and enhances EMT induced by TGF-beta in mammary epithelial cells via a MMP-dependent mechanism.

Lee YH, Albig AR, Regner M, Schiemann BJ, Schiemann WP.

Carcinogenesis. 2008 Dec;29(12):2243-51. doi: 10.1093/carcin/bgn199. Epub 2008 Aug 19.

PMID:
18713838
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The pathophysiology of epithelial-mesenchymal transition induced by transforming growth factor-beta in normal and malignant mammary epithelial cells.

Taylor MA, Parvani JG, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2010 Jun;15(2):169-90. doi: 10.1007/s10911-010-9181-1. Epub 2010 May 15. Review.

PMID:
20467795
[PubMed - indexed for MEDLINE]
Free PMC Article
3.
4.

The use of cystatin C to inhibit epithelial-mesenchymal transition and morphological transformation stimulated by transforming growth factor-beta.

Sokol JP, Neil JR, Schiemann BJ, Schiemann WP.

Breast Cancer Res. 2005;7(5):R844-53. Epub 2005 Aug 23.

PMID:
16168131
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cox-2 inactivates Smad signaling and enhances EMT stimulated by TGF-beta through a PGE2-dependent mechanisms.

Neil JR, Johnson KM, Nemenoff RA, Schiemann WP.

Carcinogenesis. 2008 Nov;29(11):2227-35. doi: 10.1093/carcin/bgn202. Epub 2008 Aug 25.

PMID:
18725385
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Activated Abl kinase inhibits oncogenic transforming growth factor-beta signaling and tumorigenesis in mammary tumors.

Allington TM, Galliher-Beckley AJ, Schiemann WP.

FASEB J. 2009 Dec;23(12):4231-43. doi: 10.1096/fj.09-138412. Epub 2009 Aug 18.

PMID:
19690215
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Lysyl oxidase contributes to mechanotransduction-mediated regulation of transforming growth factor-β signaling in breast cancer cells.

Taylor MA, Amin JD, Kirschmann DA, Schiemann WP.

Neoplasia. 2011 May;13(5):406-18.

PMID:
21532881
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Transforming growth factor-β-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression.

Wendt MK, Smith JA, Schiemann WP.

Oncogene. 2010 Dec 9;29(49):6485-98. doi: 10.1038/onc.2010.377. Epub 2010 Aug 30.

PMID:
20802523
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The Cain and Abl of epithelial-mesenchymal transition and transforming growth factor-β in mammary epithelial cells.

Allington TM, Schiemann WP.

Cells Tissues Organs. 2011;193(1-2):98-113. doi: 10.1159/000320163. Epub 2010 Nov 3. Review.

PMID:
21051857
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Transcriptome profiling of a TGF-beta-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies.

Lenferink AE, Cantin C, Nantel A, Wang E, Durocher Y, Banville M, Paul-Roc B, Marcil A, Wilson MR, O'Connor-McCourt MD.

Oncogene. 2010 Feb 11;29(6):831-44. doi: 10.1038/onc.2009.399. Epub 2009 Nov 23.

PMID:
19935703
[PubMed - indexed for MEDLINE]
11.

Noncanonical TGF-β signaling during mammary tumorigenesis.

Parvani JG, Taylor MA, Schiemann WP.

J Mammary Gland Biol Neoplasia. 2011 Jun;16(2):127-46. doi: 10.1007/s10911-011-9207-3. Epub 2011 Mar 31. Review.

PMID:
21448580
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta.

Galliher-Beckley AJ, Schiemann WP.

Carcinogenesis. 2008 Feb;29(2):244-51. doi: 10.1093/carcin/bgm245. Epub 2008 Jan 3.

PMID:
18174260
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

PGE2 receptor EP2 mediates the antagonistic effect of COX-2 on TGF-beta signaling during mammary tumorigenesis.

Tian M, Schiemann WP.

FASEB J. 2010 Apr;24(4):1105-16. doi: 10.1096/fj.09-141341. Epub 2009 Nov 6.

PMID:
19897661
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.

Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T.

J Clin Invest. 2004 Aug;114(4):569-81.

PMID:
15314694
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer.

Johansson J, Berg T, Kurzejamska E, Pang MF, Tabor V, Jansson M, Roswall P, Pietras K, Sund M, Religa P, Fuxe J.

Oncogene. 2013 Dec 12;32(50):5614-24. doi: 10.1038/onc.2013.322. Epub 2013 Aug 19.

PMID:
23955085
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MIR-99a and MIR-99b modulate TGF-β induced epithelial to mesenchymal plasticity in normal murine mammary gland cells.

Turcatel G, Rubin N, El-Hashash A, Warburton D.

PLoS One. 2012;7(1):e31032. doi: 10.1371/journal.pone.0031032. Epub 2012 Jan 27.

PMID:
22299047
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells.

Park CY, Kim DK, Sheen YY.

Cancer Sci. 2011 Oct;102(10):1889-96. doi: 10.1111/j.1349-7006.2011.02014.x. Epub 2011 Jul 29.

PMID:
21707864
[PubMed - indexed for MEDLINE]
18.

Targeted inactivation of β1 integrin induces β3 integrin switching, which drives breast cancer metastasis by TGF-β.

Parvani JG, Galliher-Beckley AJ, Schiemann BJ, Schiemann WP.

Mol Biol Cell. 2013 Nov;24(21):3449-59. doi: 10.1091/mbc.E12-10-0776. Epub 2013 Sep 4. Erratum in: Mol Biol Cell. 2014 Feb;25(4):548.

PMID:
24006485
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Wild-type and mutant p53 differentially regulate NADPH oxidase 4 in TGF-β-mediated migration of human lung and breast epithelial cells.

Boudreau HE, Casterline BW, Burke DJ, Leto TL.

Br J Cancer. 2014 May 13;110(10):2569-82. doi: 10.1038/bjc.2014.165. Epub 2014 Apr 8.

PMID:
24714748
[PubMed - indexed for MEDLINE]
20.

RGC-32 mediates transforming growth factor-beta-induced epithelial-mesenchymal transition in human renal proximal tubular cells.

Huang WY, Li ZG, Rus H, Wang X, Jose PA, Chen SY.

J Biol Chem. 2009 Apr 3;284(14):9426-32. doi: 10.1074/jbc.M900039200. Epub 2009 Jan 21.

PMID:
19158077
[PubMed - indexed for MEDLINE]
Free PMC Article

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