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Results: 1 to 20 of 360

1.

Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion.

Shida D, Fang X, Kordula T, Takabe K, Lépine S, Alvarez SE, Milstien S, Spiegel S.

Cancer Res. 2008 Aug 15;68(16):6569-77. doi: 10.1158/0008-5472.CAN-08-0411.

PMID:
18701480
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Sphingosine-1-phosphate and interleukin-1 independently regulate plasminogen activator inhibitor-1 and urokinase-type plasminogen activator receptor expression in glioblastoma cells: implications for invasiveness.

Bryan L, Paugh BS, Kapitonov D, Wilczynska KM, Alvarez SM, Singh SK, Milstien S, Spiegel S, Kordula T.

Mol Cancer Res. 2008 Sep;6(9):1469-77. doi: 10.1158/1541-7786.MCR-08-0082.

PMID:
18819934
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Bioactive lipids lysophosphatidic acid and sphingosine 1-phosphate mediate breast cancer cell biological functions through distinct mechanisms.

Boucharaba A, Guillet B, Menaa F, Hneino M, van Wijnen AJ, Clézardin P, Peyruchaud O.

Oncol Res. 2009;18(4):173-84. Erratum in: Oncol Res. 2009;18(7):357. Philippe, Clézardin [corrected to Clézardin, Philippe]; Oliver, Peyruchaud [corrected to Peyruchaud, Oliver].

PMID:
20112503
[PubMed - indexed for MEDLINE]
4.

Expression of sphingosine-1-phosphate receptors and lysophosphatidic acid receptors on cultured and xenografted human colon, breast, melanoma, and lung tumor cells.

Müller R, Berliner C, Leptin J, Pörtner D, Bialecki W, Kleuser B, Schumacher U, Milićević NM.

Tumour Biol. 2010 Aug;31(4):341-9. doi: 10.1007/s13277-010-0043-7. Epub 2010 May 18.

PMID:
20480410
[PubMed - indexed for MEDLINE]
5.

Estradiol induces export of sphingosine 1-phosphate from breast cancer cells via ABCC1 and ABCG2.

Takabe K, Kim RH, Allegood JC, Mitra P, Ramachandran S, Nagahashi M, Harikumar KB, Hait NC, Milstien S, Spiegel S.

J Biol Chem. 2010 Apr 2;285(14):10477-86. doi: 10.1074/jbc.M109.064162. Epub 2010 Jan 28.

PMID:
20110355
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Sphingosine kinase 1 enhances colon cancer cell proliferation and invasion by upregulating the production of MMP-2/9 and uPA via MAPK pathways.

Liu SQ, Huang JA, Qin MB, Su YJ, Lai MY, Jiang HX, Tang GD.

Int J Colorectal Dis. 2012 Dec;27(12):1569-78. doi: 10.1007/s00384-012-1510-y. Epub 2012 Jun 9.

PMID:
22684547
[PubMed - indexed for MEDLINE]
7.

Sphingosine-1-phosphate receptor-3 signaling up-regulates epidermal growth factor receptor and enhances epidermal growth factor receptor-mediated carcinogenic activities in cultured lung adenocarcinoma cells.

Hsu A, Zhang W, Lee JF, An J, Ekambaram P, Liu J, Honn KV, Klinge CM, Lee MJ.

Int J Oncol. 2012 May;40(5):1619-26. doi: 10.3892/ijo.2012.1379. Epub 2012 Feb 16.

PMID:
22344462
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Signal transduction responses to lysophosphatidic acid and sphingosine 1-phosphate in human prostate cancer cells.

Gibbs TC, Rubio MV, Zhang Z, Xie Y, Kipp KR, Meier KE.

Prostate. 2009 Oct 1;69(14):1493-506. doi: 10.1002/pros.20994.

PMID:
19536794
[PubMed - indexed for MEDLINE]
9.

LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells.

Chen M, Towers LN, O'Connor KL.

Am J Physiol Cell Physiol. 2007 May;292(5):C1927-33.

PMID:
17496233
[PubMed - indexed for MEDLINE]
Free Article
10.

Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription.

Ramachandran S, Shida D, Nagahashi M, Fang X, Milstien S, Takabe K, Spiegel S.

FEBS Lett. 2010 Sep 24;584(18):4077-82. doi: 10.1016/j.febslet.2010.08.035. Epub 2010 Sep 7.

PMID:
20804754
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen.

Schröder M, Richter C, Juan MH, Maltusch K, Giegold O, Quintini G, Pfeilschifter JM, Huwiler A, Radeke HH.

Mol Immunol. 2011 May;48(9-10):1139-48. doi: 10.1016/j.molimm.2011.02.007. Epub 2011 Mar 23.

PMID:
21435724
[PubMed - indexed for MEDLINE]
12.

Sphingosine kinase 1 promotes tumour cell migration and invasion via the S1P/EDG1 axis in hepatocellular carcinoma.

Bao M, Chen Z, Xu Y, Zhao Y, Zha R, Huang S, Liu L, Chen T, Li J, Tu H, He X.

Liver Int. 2012 Feb;32(2):331-8. doi: 10.1111/j.1478-3231.2011.02666.x. Epub 2011 Oct 30.

PMID:
22098666
[PubMed - indexed for MEDLINE]
13.

Sphingosine 1-phosphate receptor 4 uses HER2 (ERBB2) to regulate extracellular signal regulated kinase-1/2 in MDA-MB-453 breast cancer cells.

Long JS, Fujiwara Y, Edwards J, Tannahill CL, Tigyi G, Pyne S, Pyne NJ.

J Biol Chem. 2010 Nov 12;285(46):35957-66. doi: 10.1074/jbc.M110.117945. Epub 2010 Sep 13.

PMID:
20837468
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sphingosine-1-phosphate regulates glioblastoma cell invasiveness through the urokinase plasminogen activator system and CCN1/Cyr61.

Young N, Pearl DK, Van Brocklyn JR.

Mol Cancer Res. 2009 Jan;7(1):23-32. doi: 10.1158/1541-7786.MCR-08-0061.

PMID:
19147534
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Tumor cell invasion of collagen matrices requires coordinate lipid agonist-induced G-protein and membrane-type matrix metalloproteinase-1-dependent signaling.

Fisher KE, Pop A, Koh W, Anthis NJ, Saunders WB, Davis GE.

Mol Cancer. 2006 Dec 8;5:69.

PMID:
17156449
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Sphingosine kinase 1 plays a role in the upregulation of CD44 expression through extracellular signal-regulated kinase signaling in human colon cancer cells.

Kawahara S, Otsuji Y, Nakamura M, Murakami M, Murate T, Matsunaga T, Kanoh H, Seishima M, Banno Y, Hara A.

Anticancer Drugs. 2013 Jun;24(5):473-83. doi: 10.1097/CAD.0b013e32835f705f.

PMID:
23426175
[PubMed - indexed for MEDLINE]
17.

Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis.

Nagahashi M, Ramachandran S, Kim EY, Allegood JC, Rashid OM, Yamada A, Zhao R, Milstien S, Zhou H, Spiegel S, Takabe K.

Cancer Res. 2012 Feb 1;72(3):726-35. doi: 10.1158/0008-5472.CAN-11-2167.

PMID:
22298596
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Potentiation of growth factor signaling by insulin-like growth factor-binding protein-3 in breast epithelial cells requires sphingosine kinase activity.

Martin JL, Lin MZ, McGowan EM, Baxter RC.

J Biol Chem. 2009 Sep 18;284(38):25542-52. doi: 10.1074/jbc.M109.007120. Epub 2009 Jul 25.

PMID:
19633297
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Biochemical regulation of breast cancer cell expression of S1P2 (Edg-5) and S1P3 (Edg-3) G protein-coupled receptors for sphingosine 1-phosphate.

Dolezalova H, Shankar G, Huang MC, Bikle DD, Goetzl EJ.

J Cell Biochem. 2003 Mar 1;88(4):732-43.

PMID:
12577307
[PubMed - indexed for MEDLINE]
20.

Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells.

Yu S, Murph MM, Lu Y, Liu S, Hall HS, Liu J, Stephens C, Fang X, Mills GB.

J Natl Cancer Inst. 2008 Nov 19;100(22):1630-42. doi: 10.1093/jnci/djn378. Epub 2008 Nov 11.

PMID:
19001604
[PubMed - indexed for MEDLINE]
Free PMC Article

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