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Results: 1 to 20 of 129

Similar articles for PubMed (Select 18697945)

1.

Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage.

Berman SD, Calo E, Landman AS, Danielian PS, Miller ES, West JC, Fonhoue BD, Caron A, Bronson R, Bouxsein ML, Mukherjee S, Lees JA.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11851-6. doi: 10.1073/pnas.0805462105. Epub 2008 Aug 12.

2.

Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.

Lengner CJ, Steinman HA, Gagnon J, Smith TW, Henderson JE, Kream BE, Stein GS, Lian JB, Jones SN.

J Cell Biol. 2006 Mar 13;172(6):909-21.

3.

The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development.

Rubio R, Gutierrez-Aranda I, Sáez-Castillo AI, Labarga A, Rosu-Myles M, Gonzalez-Garcia S, Toribio ML, Menendez P, Rodriguez R.

Oncogene. 2013 Oct 10;32(41):4970-80. doi: 10.1038/onc.2012.507. Epub 2012 Dec 10.

PMID:
23222711
4.

Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).

Pereira BP, Zhou Y, Gupta A, Leong DT, Aung KZ, Ling L, Pho RW, Galindo M, Salto-Tellez M, Stein GS, Cool SM, van Wijnen AJ, Nathan SS.

J Cell Physiol. 2009 Dec;221(3):778-88. doi: 10.1002/jcp.21921.

5.

Sox2 maintains self renewal of tumor-initiating cells in osteosarcomas.

Basu-Roy U, Seo E, Ramanathapuram L, Rapp TB, Perry JA, Orkin SH, Mansukhani A, Basilico C.

Oncogene. 2012 May 3;31(18):2270-82. doi: 10.1038/onc.2011.405. Epub 2011 Sep 19.

6.

The MET oncogene transforms human primary bone-derived cells into osteosarcomas by targeting committed osteo-progenitors.

Dani N, Olivero M, Mareschi K, van Duist MM, Miretti S, Cuvertino S, Patané S, Calogero R, Ferracini R, Scotlandi K, Fagioli F, Di Renzo MF.

J Bone Miner Res. 2012 Jun;27(6):1322-34. doi: 10.1002/jbmr.1578.

PMID:
22367914
7.

Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells.

Rubio R, Abarrategi A, Garcia-Castro J, Martinez-Cruzado L, Suarez C, Tornin J, Santos L, Astudillo A, Colmenero I, Mulero F, Rosu-Myles M, Menendez P, Rodriguez R.

Stem Cells. 2014 May;32(5):1136-48. doi: 10.1002/stem.1647.

PMID:
24446210
8.

Modeling distinct osteosarcoma subtypes in vivo using Cre:lox and lineage-restricted transgenic shRNA.

Mutsaers AJ, Ng AJ, Baker EK, Russell MR, Chalk AM, Wall M, Liddicoat BJ, Ho PW, Slavin JL, Goradia A, Martin TJ, Purton LE, Dickins RA, Walkley CR.

Bone. 2013 Jul;55(1):166-78. doi: 10.1016/j.bone.2013.02.016. Epub 2013 Feb 26.

PMID:
23486187
9.

Local mesenchymal stem/progenitor cells are a preferential target for initiation of adult soft tissue sarcomas associated with p53 and Rb deficiency.

Choi J, Curtis SJ, Roy DM, Flesken-Nikitin A, Nikitin AY.

Am J Pathol. 2010 Nov;177(5):2645-58. doi: 10.2353/ajpath.2010.100306. Epub 2010 Sep 23.

10.

Morphological and biological heterogeneity of three tumorigenic cell lines derived from a single p53-/- osteoblast-like cell line, MMC2.

Murakami H, Nakayama T, Nishijo K, Hosaka T, Nakamata T, Aoyama T, Okamoto T, Tsuboyama T, Nakamura T, Toguchida J.

Cancer Lett. 2002 Aug 28;182(2):203-11.

PMID:
12048166
11.

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease.

Walkley CR, Qudsi R, Sankaran VG, Perry JA, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP, Orkin SH.

Genes Dev. 2008 Jun 15;22(12):1662-76. doi: 10.1101/gad.1656808.

12.

The retinoblastoma protein in osteoblast differentiation and osteosarcoma.

Deshpande A, Hinds PW.

Curr Mol Med. 2006 Nov;6(7):809-17. Review.

PMID:
17100605
13.

Human osteosarcoma CD49f(-)CD133(+) cells: impaired in osteogenic fate while gain of tumorigenicity.

Ying M, Liu G, Shimada H, Ding W, May WA, He Q, Adams GB, Wu L.

Oncogene. 2013 Sep 5;32(36):4252-63. doi: 10.1038/onc.2012.438. Epub 2012 Oct 8.

14.

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.

Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, Gutierrez GM, Piscopo DM, Carty SA, Hinds PW.

J Cell Biol. 2004 Dec 6;167(5):925-34.

15.

Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2.

Mohseny AB, Szuhai K, Romeo S, Buddingh EP, Briaire-de Bruijn I, de Jong D, van Pel M, Cleton-Jansen AM, Hogendoorn PC.

J Pathol. 2009 Nov;219(3):294-305. doi: 10.1002/path.2603.

PMID:
19718709
16.

Self-renewing Pten-/- TP53-/- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity.

Abou-Kheir W, Hynes PG, Martin P, Yin JJ, Liu YN, Seng V, Lake R, Spurrier J, Kelly K.

PLoS One. 2011;6(10):e26112. doi: 10.1371/journal.pone.0026112. Epub 2011 Oct 11.

17.

Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells.

Di Fiore R, Marcatti M, Drago-Ferrante R, D'Anneo A, Giuliano M, Carlisi D, De Blasio A, Querques F, Pastore L, Tesoriere G, Vento R.

Bone. 2014 Mar;60:198-212. doi: 10.1016/j.bone.2013.12.021. Epub 2013 Dec 27.

PMID:
24373920
18.

Elevated p53 RNA expression correlates with incomplete osteogenic differentiation of radiation-induced murine osteosarcomas.

Strauss PG, Mitreiter K, Zitzelsberger H, Luz A, Schmidt J, Erfle V, Höfler H.

Int J Cancer. 1992 Jan 21;50(2):252-8.

PMID:
1730519
19.

Metastasis is an early event in mouse mammary carcinomas and is associated with cells bearing stem cell markers.

Weng D, Penzner JH, Song B, Koido S, Calderwood SK, Gong J.

Breast Cancer Res. 2012 Jan 25;14(1):R18.

20.

Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.

Nathan SS, Pereira BP, Zhou YF, Gupta A, Dombrowski C, Soong R, Pho RW, Stein GS, Salto-Tellez M, Cool SM, van Wijnen AJ.

Mol Biol Rep. 2009 Jan;36(1):153-8. doi: 10.1007/s11033-008-9378-1. Epub 2008 Oct 18.

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