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A Cdo-Bnip-2-Cdc42 signaling pathway regulates p38alpha/beta MAPK activity and myogenic differentiation.

Kang JS, Bae GU, Yi MJ, Yang YJ, Oh JE, Takaesu G, Zhou YT, Low BC, Krauss RS.

J Cell Biol. 2008 Aug 11;182(3):497-507. doi: 10.1083/jcb.200801119. Epub 2008 Aug 4.


Activation of p38alpha/beta MAPK in myogenesis via binding of the scaffold protein JLP to the cell surface protein Cdo.

Takaesu G, Kang JS, Bae GU, Yi MJ, Lee CM, Reddy EP, Krauss RS.

J Cell Biol. 2006 Nov 6;175(3):383-8. Epub 2006 Oct 30.


Cdo binds Abl to promote p38alpha/beta mitogen-activated protein kinase activity and myogenic differentiation.

Bae GU, Kim BG, Lee HJ, Oh JE, Lee SJ, Zhang W, Krauss RS, Kang JS.

Mol Cell Biol. 2009 Aug;29(15):4130-43. doi: 10.1128/MCB.00199-09. Epub 2009 May 26.


N-cadherin ligation, but not Sonic hedgehog binding, initiates Cdo-dependent p38alpha/beta MAPK signaling in skeletal myoblasts.

Lu M, Krauss RS.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4212-7. doi: 10.1073/pnas.0908883107. Epub 2010 Feb 16.


Cdo promotes neuronal differentiation via activation of the p38 mitogen-activated protein kinase pathway.

Oh JE, Bae GU, Yang YJ, Yi MJ, Lee HJ, Kim BG, Krauss RS, Kang JS.

FASEB J. 2009 Jul;23(7):2088-99. doi: 10.1096/fj.08-119255. Epub 2009 Feb 25.


Promyogenic function of Integrin/FAK signaling is mediated by Cdo, Cdc42 and MyoD.

Han JW, Lee HJ, Bae GU, Kang JS.

Cell Signal. 2011 Jul;23(7):1162-9. doi: 10.1016/j.cellsig.2011.03.001. Epub 2011 Mar 17.


Cdo interacts with APPL1 and activates Akt in myoblast differentiation.

Bae GU, Lee JR, Kim BG, Han JW, Leem YE, Lee HJ, Ho SM, Hahn MJ, Kang JS.

Mol Biol Cell. 2010 Jul 15;21(14):2399-411. doi: 10.1091/mbc.E09-12-1011. Epub 2010 May 19.


TGF-β-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) interact with the promyogenic receptor Cdo to promote myogenic differentiation via activation of p38MAPK pathway.

Tran P, Ho SM, Kim BG, Vuong TA, Leem YE, Bae GU, Kang JS.

J Biol Chem. 2012 Apr 6;287(15):11602-15. doi: 10.1074/jbc.M112.351601. Epub 2012 Feb 15.


Gas1 cooperates with Cdo and promotes myogenic differentiation via activation of p38MAPK.

Leem YE, Han JW, Lee HJ, Ha HL, Kwon YL, Ho SM, Kim BG, Tran P, Bae GU, Kang JS.

Cell Signal. 2011 Dec;23(12):2021-9. doi: 10.1016/j.cellsig.2011.07.016. Epub 2011 Jul 24.


KIF5B transports BNIP-2 to regulate p38 mitogen-activated protein kinase activation and myoblast differentiation.

Yi P, Chew LL, Zhang Z, Ren H, Wang F, Cong X, Zheng L, Luo Y, Ouyang H, Low BC, Zhou YT.

Mol Biol Cell. 2015 Jan 1;26(1):29-42. doi: 10.1091/mbc.E14-03-0797. Epub 2014 Nov 5.


Abl promotes cadherin-dependent adhesion and signaling in myoblasts.

Lu M, Krauss RS.

Cell Cycle. 2010 Jul 15;9(14):2737-41. Epub 2010 Jul 28.


Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation.

Lovett FA, Gonzalez I, Salih DA, Cobb LJ, Tripathi G, Cosgrove RA, Murrell A, Kilshaw PJ, Pell JM.

J Cell Sci. 2006 Dec 1;119(Pt 23):4828-40. Epub 2006 Nov 14.


Genetic analysis of p38 MAP kinases in myogenesis: fundamental role of p38alpha in abrogating myoblast proliferation.

Perdiguero E, Ruiz-Bonilla V, Gresh L, Hui L, Ballestar E, Sousa-Victor P, Baeza-Raja B, Jardí M, Bosch-Comas A, Esteller M, Caelles C, Serrano AL, Wagner EF, Muñoz-Cánoves P.

EMBO J. 2007 Mar 7;26(5):1245-56. Epub 2007 Feb 15.


The neurite outgrowth multiadaptor RhoGAP, NOMA-GAP, regulates neurite extension through SHP2 and Cdc42.

Rosário M, Franke R, Bednarski C, Birchmeier W.

J Cell Biol. 2007 Jul 30;178(3):503-16.


Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo-activated ERK1/2 is critical for the promyogenic function of Stim1.

Lee HJ, Bae GU, Leem YE, Choi HK, Kang TM, Cho H, Kim ST, Kang JS.

Mol Biol Cell. 2012 Apr;23(7):1376-87. doi: 10.1091/mbc.E11-07-0634. Epub 2012 Feb 1.


A novel connection between the yeast Cdc42 GTPase and the Slt2-mediated cell integrity pathway identified through the effect of secreted Salmonella GTPase modulators.

Rodríguez-Pachón JM, Martín H, North G, Rotger R, Nombela C, Molina M.

J Biol Chem. 2002 Jul 26;277(30):27094-102. Epub 2002 May 16.


PKR is a novel functional direct player that coordinates skeletal muscle differentiation via p38MAPK/AKT pathways.

Alisi A, Spaziani A, Anticoli S, Ghidinelli M, Balsano C.

Cell Signal. 2008 Mar;20(3):534-42. doi: 10.1016/j.cellsig.2007.11.006. Epub 2007 Nov 26.

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