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Similar articles for PubMed (Select 18635356)


PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.

Kamimura Y, Xiong Y, Iglesias PA, Hoeller O, Bolourani P, Devreotes PN.

Curr Biol. 2008 Jul 22;18(14):1034-43. doi: 10.1016/j.cub.2008.06.068.


Assays for chemotaxis and chemoattractant-stimulated TorC2 activation and PKB substrate phosphorylation in Dictyostelium.

Kamimura Y, Tang M, Devreotes P.

Methods Mol Biol. 2009;571:255-70. doi: 10.1007/978-1-60761-198-1_17.


Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis.

Cai H, Das S, Kamimura Y, Long Y, Parent CA, Devreotes PN.

J Cell Biol. 2010 Jul 26;190(2):233-45. doi: 10.1083/jcb.201001129.


TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.

Lee S, Comer FI, Sasaki A, McLeod IX, Duong Y, Okumura K, Yates JR 3rd, Parent CA, Firtel RA.

Mol Biol Cell. 2005 Oct;16(10):4572-83. Epub 2005 Aug 3.


A Ras signaling complex controls the RasC-TORC2 pathway and directed cell migration.

Charest PG, Shen Z, Lakoduk A, Sasaki AT, Briggs SP, Firtel RA.

Dev Cell. 2010 May 18;18(5):737-49. doi: 10.1016/j.devcel.2010.03.017.


Involvement of the cytoskeleton in controlling leading-edge function during chemotaxis.

Lee S, Shen Z, Robinson DN, Briggs S, Firtel RA.

Mol Biol Cell. 2010 Jun 1;21(11):1810-24. doi: 10.1091/mbc.E10-01-0009. Epub 2010 Apr 7.


Disruption of PKB signaling restores polarity to cells lacking tumor suppressor PTEN.

Tang M, Iijima M, Kamimura Y, Chen L, Long Y, Devreotes P.

Mol Biol Cell. 2011 Feb 15;22(4):437-47. doi: 10.1091/mbc.E10-06-0522. Epub 2010 Dec 17.


Phosphorylation of chemoattractant receptors regulates chemotaxis, actin reorganization and signal relay.

Brzostowski JA, Sawai S, Rozov O, Liao XH, Imoto D, Parent CA, Kimmel AR.

J Cell Sci. 2013 Oct 15;126(Pt 20):4614-26. doi: 10.1242/jcs.122952. Epub 2013 Jul 31.


Daydreamer, a Ras effector and GSK-3 substrate, is important for directional sensing and cell motility.

Kölsch V, Shen Z, Lee S, Plak K, Lotfi P, Chang J, Charest PG, Romero JL, Jeon TJ, Kortholt A, Briggs SP, Firtel RA.

Mol Biol Cell. 2013 Jan;24(2):100-14. doi: 10.1091/mbc.E12-04-0271. Epub 2012 Nov 7.


Spatiotemporal regulation of Ras activity provides directional sensing.

Zhang S, Charest PG, Firtel RA.

Curr Biol. 2008 Oct 28;18(20):1587-93. doi: 10.1016/j.cub.2008.08.069.


Tumor suppressor Hippo/MST1 kinase mediates chemotaxis by regulating spreading and adhesion.

Artemenko Y, Batsios P, Borleis J, Gagnon Z, Lee J, Rohlfs M, Sanséau D, Willard SS, Schleicher M, Devreotes PN.

Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13632-7. doi: 10.1073/pnas.1211304109. Epub 2012 Jul 30.


Feedback signaling controls leading-edge formation during chemotaxis.

Charest PG, Firtel RA.

Curr Opin Genet Dev. 2006 Aug;16(4):339-47. Epub 2006 Jun 27. Review.

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