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Results: 1 to 20 of 101

Related Citations for PubMed (Select 18621677)

1.

A synthetic mammalian gene circuit reveals antituberculosis compounds.

Weber W, Schoenmakers R, Keller B, Gitzinger M, Grau T, Daoud-El Baba M, Sander P, Fussenegger M.

Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9994-8. doi: 10.1073/pnas.0800663105. Epub 2008 Jul 9.

2.

EthR, a repressor of the TetR/CamR family implicated in ethionamide resistance in mycobacteria, octamerizes cooperatively on its operator.

Engohang-Ndong J, Baillat D, Aumercier M, Bellefontaine F, Besra GS, Locht C, Baulard AR.

Mol Microbiol. 2004 Jan;51(1):175-88.

PMID:
14651620
3.

Phenylethyl butyrate enhances the potency of second-line drugs against clinical isolates of Mycobacterium tuberculosis.

Grau T, Selchow P, Tigges M, Burri R, Gitzinger M, Böttger EC, Fussenegger M, Sander P.

Antimicrob Agents Chemother. 2012 Feb;56(2):1142-5. doi: 10.1128/AAC.05649-11. Epub 2011 Nov 21.

4.

An ethA-ethR-deficient Mycobacterium bovis BCG mutant displays increased adherence to mammalian cells and greater persistence in vivo, which correlate with altered mycolic acid composition.

Ang ML, Zainul Rahim SZ, Shui G, Dianiškova P, Madacki J, Lin W, Koh VH, Martinez Gomez JM, Sudarkodi S, Bendt A, Wenk M, Mikušová K, Korduláková J, Pethe K, Alonso S.

Infect Immun. 2014 May;82(5):1850-9. doi: 10.1128/IAI.01332-13. Epub 2014 Feb 24. Erratum in: Infect Immun. 2015 Feb;83(2):846. Siti, Zarina Zainul Rahim [corrected to Zainul Rahim, Siti Zarina].

5.

Insights into mechanisms of induction and ligands recognition in the transcriptional repressor EthR from Mycobacterium tuberculosis.

Frénois F, Baulard AR, Villeret V.

Tuberculosis (Edinb). 2006 Mar;86(2):110-4. Epub 2005 Oct 21. Review.

PMID:
16243584
6.

Structure of EthR in a ligand bound conformation reveals therapeutic perspectives against tuberculosis.

Frénois F, Engohang-Ndong J, Locht C, Baulard AR, Villeret V.

Mol Cell. 2004 Oct 22;16(2):301-7.

PMID:
15494316
7.

Crystal structure of the TetR/CamR family repressor Mycobacterium tuberculosis EthR implicated in ethionamide resistance.

Dover LG, Corsino PE, Daniels IR, Cocklin SL, Tatituri V, Besra GS, Fütterer K.

J Mol Biol. 2004 Jul 23;340(5):1095-105.

PMID:
15236969
8.

The Mycobacterium tuberculosis transcriptional repressor EthR is negatively regulated by Serine/Threonine phosphorylation.

Leiba J, Carrère-Kremer S, Blondiaux N, Dimala MM, Wohlkönig A, Baulard A, Kremer L, Molle V.

Biochem Biophys Res Commun. 2014 Apr 18;446(4):1132-8. doi: 10.1016/j.bbrc.2014.03.074. Epub 2014 Mar 22.

PMID:
24667600
9.

Discovery of novel N-phenylphenoxyacetamide derivatives as EthR inhibitors and ethionamide boosters by combining high-throughput screening and synthesis.

Flipo M, Willand N, Lecat-Guillet N, Hounsou C, Desroses M, Leroux F, Lens Z, Villeret V, Wohlkönig A, Wintjens R, Christophe T, Kyoung Jeon H, Locht C, Brodin P, Baulard AR, Déprez B.

J Med Chem. 2012 Jul 26;55(14):6391-402. doi: 10.1021/jm300377g. Epub 2012 Jul 17.

PMID:
22738293
10.

The use of microarray analysis to determine the gene expression profiles of Mycobacterium tuberculosis in response to anti-bacterial compounds.

Waddell SJ, Stabler RA, Laing K, Kremer L, Reynolds RC, Besra GS.

Tuberculosis (Edinb). 2004;84(3-4):263-74.

PMID:
15207496
11.

Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system.

Milano A, Pasca MR, Provvedi R, Lucarelli AP, Manina G, Ribeiro AL, Manganelli R, Riccardi G.

Tuberculosis (Edinb). 2009 Jan;89(1):84-90. doi: 10.1016/j.tube.2008.08.003. Epub 2008 Oct 11.

PMID:
18851927
12.

Ethionamide boosters. 2. Combining bioisosteric replacement and structure-based drug design to solve pharmacokinetic issues in a series of potent 1,2,4-oxadiazole EthR inhibitors.

Flipo M, Desroses M, Lecat-Guillet N, Villemagne B, Blondiaux N, Leroux F, Piveteau C, Mathys V, Flament MP, Siepmann J, Villeret V, Wohlkönig A, Wintjens R, Soror SH, Christophe T, Jeon HK, Locht C, Brodin P, Déprez B, Baulard AR, Willand N.

J Med Chem. 2012 Jan 12;55(1):68-83. doi: 10.1021/jm200825u. Epub 2011 Dec 6.

PMID:
22098589
13.

Loss of oxyR in Mycobacterium tuberculosis.

Deretic V, Song J, Pagán-Ramos E.

Trends Microbiol. 1997 Sep;5(9):367-72. Review.

PMID:
9294894
14.

Assessment of efflux pump gene expression in a clinical isolate Mycobacterium tuberculosis by real-time reverse transcription PCR.

Jiang X, Zhang W, Zhang Y, Gao F, Lu C, Zhang X, Wang H.

Microb Drug Resist. 2008 Mar;14(1):7-11. doi: 10.1089/mdr.2008.0772.

PMID:
18321205
15.

Synthetic EthR inhibitors boost antituberculous activity of ethionamide.

Willand N, Dirié B, Carette X, Bifani P, Singhal A, Desroses M, Leroux F, Willery E, Mathys V, Déprez-Poulain R, Delcroix G, Frénois F, Aumercier M, Locht C, Villeret V, Déprez B, Baulard AR.

Nat Med. 2009 May;15(5):537-44. doi: 10.1038/nm.1950. Epub 2009 May 3.

PMID:
19412174
16.

Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis.

Alahari A, Alibaud L, Trivelli X, Gupta R, Lamichhane G, Reynolds RC, Bishai WR, Guerardel Y, Kremer L.

Mol Microbiol. 2009 Mar;71(5):1263-77. doi: 10.1111/j.1365-2958.2009.06604.x. Epub 2009 Jan 15.

PMID:
19183278
17.

Purification and characterization of anthranilate synthase component I (TrpE) from Mycobacterium tuberculosis H37Rv.

Lin X, Xu S, Yang Y, Wu J, Wang H, Shen H, Wang H.

Protein Expr Purif. 2009 Mar;64(1):8-15. doi: 10.1016/j.pep.2008.09.020. Epub 2008 Oct 10.

PMID:
18952181
18.

Targeting iron acquisition by Mycobacterium tuberculosis.

Monfeli RR, Beeson C.

Infect Disord Drug Targets. 2007 Sep;7(3):213-20. Review.

PMID:
17897057
19.

[Problems of screening novel antituberculosis antibiotics. 3. New data on mechanism of action of antituberculosis agents].

Bibikova MV, Borisova NA, Orekhov SN, Katlinskiĭ AV.

Antibiot Khimioter. 2006;51(7):34-40. Review. Russian. No abstract available.

PMID:
18035732
20.

Detection of mutations in Mycobacterium tuberculosis genome determining resistance to fluoroquinolones by hybridization on biological microchips.

Antonova OV, Gryadunov DA, Lapa SA, Kuz'min AV, Larionova EE, Smirnova TG, Nosova EY, Skotnikova OI, Chernousova LN, Moroz AM, Zasedatelev AS, Mikhailovich VM.

Bull Exp Biol Med. 2008 Jan;145(1):108-13.

PMID:
19024017
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