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Results: 1 to 20 of 101

1.

Shc coordinates signals from intercellular junctions and integrins to regulate flow-induced inflammation.

Liu Y, Sweet DT, Irani-Tehrani M, Maeda N, Tzima E.

J Cell Biol. 2008 Jul 14;182(1):185-96. doi: 10.1083/jcb.200709176. Epub 2008 Jul 7.

PMID:
18606845
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism to control vascular endothelial growth factor receptor-2 signaling.

Zanetti A, Lampugnani MG, Balconi G, Breviario F, Corada M, Lanfrancone L, Dejana E.

Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):617-22.

PMID:
11950700
[PubMed - indexed for MEDLINE]
Free Article
4.

Matrix-specific protein kinase A signaling regulates p21-activated kinase activation by flow in endothelial cells.

Funk SD, Yurdagul A Jr, Green JM, Jhaveri KA, Schwartz MA, Orr AW.

Circ Res. 2010 Apr 30;106(8):1394-403. doi: 10.1161/CIRCRESAHA.109.210286. Epub 2010 Mar 11.

PMID:
20224042
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Interplay between integrins and FLK-1 in shear stress-induced signaling.

Wang Y, Miao H, Li S, Chen KD, Li YS, Yuan S, Shyy JY, Chien S.

Am J Physiol Cell Physiol. 2002 Nov;283(5):C1540-7.

PMID:
12372815
[PubMed - indexed for MEDLINE]
Free Article
6.

Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK.

Barberis L, Wary KK, Fiucci G, Liu F, Hirsch E, Brancaccio M, Altruda F, Tarone G, Giancotti FG.

J Biol Chem. 2000 Nov 24;275(47):36532-40.

PMID:
10976102
[PubMed - indexed for MEDLINE]
Free Article
7.

Mechanotransduction in response to shear stress. Roles of receptor tyrosine kinases, integrins, and Shc.

Chen KD, Li YS, Kim M, Li S, Yuan S, Chien S, Shyy JY.

J Biol Chem. 1999 Jun 25;274(26):18393-400.

PMID:
10373445
[PubMed - indexed for MEDLINE]
Free Article
8.

The adaptor protein Shc couples a class of integrins to the control of cell cycle progression.

Wary KK, Mainiero F, Isakoff SJ, Marcantonio EE, Giancotti FG.

Cell. 1996 Nov 15;87(4):733-43.

PMID:
8929541
[PubMed - indexed for MEDLINE]
Free Article
9.

VEGFR2 induces c-Src signaling and vascular permeability in vivo via the adaptor protein TSAd.

Sun Z, Li X, Massena S, Kutschera S, Padhan N, Gualandi L, Sundvold-Gjerstad V, Gustafsson K, Choy WW, Zang G, Quach M, Jansson L, Phillipson M, Abid MR, Spurkland A, Claesson-Welsh L.

J Exp Med. 2012 Jul 2;209(7):1363-77. doi: 10.1084/jem.20111343. Epub 2012 Jun 11.

PMID:
22689825
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Signal transduction by beta1 integrin receptors in human chondrocytes in vitro: collaboration with the insulin-like growth factor-I receptor.

Shakibaei M, John T, De Souza P, Rahmanzadeh R, Merker HJ.

Biochem J. 1999 Sep 15;342 Pt 3:615-23.

PMID:
10477272
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Altered nitric oxide production mediates matrix-specific PAK2 and NF-κB activation by flow.

Yurdagul A Jr, Chen J, Funk SD, Albert P, Kevil CG, Orr AW.

Mol Biol Cell. 2013 Feb;24(3):398-408. doi: 10.1091/mbc.E12-07-0513. Epub 2012 Nov 21.

PMID:
23171552
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Chronic physiological shear stress inhibits tumor necrosis factor-induced proinflammatory responses in rabbit aorta perfused ex vivo.

Yamawaki H, Lehoux S, Berk BC.

Circulation. 2003 Sep 30;108(13):1619-25. Epub 2003 Sep 8.

PMID:
12963644
[PubMed - indexed for MEDLINE]
Free Article
13.

The adaptor protein Shc integrates growth factor and ECM signaling during postnatal angiogenesis.

Sweet DT, Chen Z, Wiley DM, Bautch VL, Tzima E.

Blood. 2012 Feb 23;119(8):1946-55. doi: 10.1182/blood-2011-10-384560. Epub 2011 Nov 16.

PMID:
22096252
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: roles of extracellular matrix, Shc, and mitogen-activated protein kinase.

Lee DY, Yeh CR, Chang SF, Lee PL, Chien S, Cheng CK, Chiu JJ.

J Bone Miner Res. 2008 Jul;23(7):1140-9. doi: 10.1359/jbmr.080302.

PMID:
18333755
[PubMed - indexed for MEDLINE]
15.

Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.

Lee DY, Li YS, Chang SF, Zhou J, Ho HM, Chiu JJ, Chien S.

J Biol Chem. 2010 Jan 1;285(1):30-42. doi: 10.1074/jbc.M109.010512. Epub 2009 Nov 4.

PMID:
19889638
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Endothelial Shc regulates arteriogenesis through dual control of arterial specification and inflammation via the notch and nuclear factor-κ-light-chain-enhancer of activated B-cell pathways.

Sweet DT, Chen Z, Givens CS, Owens AP 3rd, Rojas M, Tzima E.

Circ Res. 2013 Jun 21;113(1):32-9. doi: 10.1161/CIRCRESAHA.113.301407. Epub 2013 May 9.

PMID:
23661718
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands.

Jalali S, del Pozo MA, Chen K, Miao H, Li Y, Schwartz MA, Shyy JY, Chien S.

Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):1042-6. Epub 2001 Jan 23.

PMID:
11158591
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon.

Piiper A, Elez R, You SJ, Kronenberger B, Loitsch S, Roche S, Zeuzem S.

J Biol Chem. 2003 Feb 28;278(9):7065-72. Epub 2002 Dec 20.

PMID:
12496267
[PubMed - indexed for MEDLINE]
Free Article
19.

Integrin activation and focal complex formation in cardiac hypertrophy.

Laser M, Willey CD, Jiang W, Cooper G 4th, Menick DR, Zile MR, Kuppuswamy D.

J Biol Chem. 2000 Nov 10;275(45):35624-30.

PMID:
10958798
[PubMed - indexed for MEDLINE]
Free Article
20.

Vascular endothelial growth factor induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes.

Takahashi N, Seko Y, Noiri E, Tobe K, Kadowaki T, Sabe H, Yazaki Y.

Circ Res. 1999 May 28;84(10):1194-202.

PMID:
10347094
[PubMed - indexed for MEDLINE]
Free Article

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