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Items: 1 to 20 of 89

1.

The NALP3 inflammasome is involved in the innate immune response to amyloid-beta.

Halle A, Hornung V, Petzold GC, Stewart CR, Monks BG, Reinheckel T, Fitzgerald KA, Latz E, Moore KJ, Golenbock DT.

Nat Immunol. 2008 Aug;9(8):857-65. doi: 10.1038/ni.1636. Epub 2008 Jul 11.

2.

Phagocytosis of amyloid-beta and inflammation: two faces of innate immunity in Alzheimer's disease.

Fiala M, Cribbs DH, Rosenthal M, Bernard G.

J Alzheimers Dis. 2007 Jul;11(4):457-63. Review.

PMID:
17656824
3.

Amyloid-beta oligomers set fire to inflammasomes and induce Alzheimer's pathology.

Salminen A, Ojala J, Suuronen T, Kaarniranta K, Kauppinen A.

J Cell Mol Med. 2008 Dec;12(6A):2255-62. doi: 10.1111/j.1582-4934.2008.00496.x. Epub 2008 Sep 13. Review.

4.

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization.

Hornung V, Bauernfeind F, Halle A, Samstad EO, Kono H, Rock KL, Fitzgerald KA, Latz E.

Nat Immunol. 2008 Aug;9(8):847-56. doi: 10.1038/ni.1631. Epub 2008 Jul 11.

5.

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation.

Shi F, Yang L, Kouadir M, Yang Y, Wang J, Zhou X, Yin X, Zhao D.

J Neuroinflammation. 2012 Jul 11;9:73. doi: 10.1186/1742-2094-9-73.

6.

The inflammasome, autoinflammatory diseases, and gout.

Pétrilli V, Martinon F.

Joint Bone Spine. 2007 Dec;74(6):571-6. Epub 2007 Aug 21. Review.

PMID:
17714972
7.

Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica.

Dostert C, Pétrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J.

Science. 2008 May 2;320(5876):674-7. doi: 10.1126/science.1156995. Epub 2008 Apr 10.

8.

Orthopedic wear debris mediated inflammatory osteolysis is mediated in part by NALP3 inflammasome activation.

Burton L, Paget D, Binder NB, Bohnert K, Nestor BJ, Sculco TP, Santambrogio L, Ross FP, Goldring SR, Purdue PE.

J Orthop Res. 2013 Jan;31(1):73-80. doi: 10.1002/jor.22190. Epub 2012 Aug 29.

9.

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants.

Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA.

Nature. 2008 Jun 19;453(7198):1122-6. doi: 10.1038/nature06939. Epub 2008 May 21.

PMID:
18496530
10.

NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice.

Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT.

Nature. 2013 Jan 31;493(7434):674-8. doi: 10.1038/nature11729. Epub 2012 Dec 19.

11.

Inflammatory components in human Alzheimer's disease and after active amyloid-β42 immunization.

Zotova E, Bharambe V, Cheaveau M, Morgan W, Holmes C, Harris S, Neal JW, Love S, Nicoll JA, Boche D.

Brain. 2013 Sep;136(Pt 9):2677-96. doi: 10.1093/brain/awt210. Epub 2013 Aug 13.

12.

Assessing β-amyloid-induced NLRP3 inflammasome activation in primary microglia.

Schnaars M, Beckert H, Halle A.

Methods Mol Biol. 2013;1040:1-8. doi: 10.1007/978-1-62703-523-1_1.

PMID:
23852592
14.

Differential pathways for interleukin-1β production activated by chromogranin A and amyloid β in microglia.

Wu Z, Sun L, Hashioka S, Yu S, Schwab C, Okada R, Hayashi Y, McGeer PL, Nakanishi H.

Neurobiol Aging. 2013 Dec;34(12):2715-25. doi: 10.1016/j.neurobiolaging.2013.05.018. Epub 2013 Jul 4.

PMID:
23831373
15.

Interleukin-1beta (IL-1beta) processing pathway.

Weber A, Wasiliew P, Kracht M.

Sci Signal. 2010 Jan 19;3(105):cm2. doi: 10.1126/scisignal.3105cm2. Review.

16.

Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation.

Rajamäki K, Lappalainen J, Oörni K, Välimäki E, Matikainen S, Kovanen PT, Eklund KK.

PLoS One. 2010 Jul 23;5(7):e11765. doi: 10.1371/journal.pone.0011765.

17.

TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation.

Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, Rübe CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K.

J Immunol. 2012 Feb 1;188(3):1098-107. doi: 10.4049/jimmunol.1101121. Epub 2011 Dec 23.

18.

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.

Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J.

Nature. 2009 Jul 9;460(7252):269-73. doi: 10.1038/nature08100. Epub 2009 Jun 3.

PMID:
19494813
19.

Antibody-mediated inhibition of integrin α5β1 blocks neurotoxic prion peptide PrP106-126-induced activation of BV2 microglia.

Chang J, Yang L, Kouadir M, Peng Y, Zhang S, Shi F, Zhou X, Yin X, Zhao D.

J Mol Neurosci. 2012 Sep;48(1):248-52. doi: 10.1007/s12031-012-9821-6. Epub 2012 May 31.

PMID:
22648512
20.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

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