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Results: 1 to 20 of 135

1.

Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction.

Zhu M, Chen M, Zuscik M, Wu Q, Wang YJ, Rosier RN, O'Keefe RJ, Chen D.

Arthritis Rheum. 2008 Jul;58(7):2053-64. doi: 10.1002/art.23614.

PMID:
18576323
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Inhibition of beta-catenin signaling causes defects in postnatal cartilage development.

Chen M, Zhu M, Awad H, Li TF, Sheu TJ, Boyce BF, Chen D, O'Keefe RJ.

J Cell Sci. 2008 May 1;121(Pt 9):1455-65. doi: 10.1242/jcs.020362. Epub 2008 Apr 8.

PMID:
18397998
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice.

Zhu M, Tang D, Wu Q, Hao S, Chen M, Xie C, Rosier RN, O'Keefe RJ, Zuscik M, Chen D.

J Bone Miner Res. 2009 Jan;24(1):12-21. doi: 10.1359/jbmr.080901.

PMID:
18767925
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Chondrocyte-specific inhibition of β-catenin signaling leads to dysplasia of the caudal vertebrae in mice.

Shu B, Li TF, Li XF, Tang DZ, Zhang Y, Shi Q, Wang YJ, Chen D.

Spine (Phila Pa 1976). 2013 Nov 15;38(24):2079-84. doi: 10.1097/01.brs.0000435024.57940.8d.

PMID:
24026150
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

α-Catenin inhibits β-catenin-T-cell factor/lymphoid enhancing factor transcriptional activity and collagen type II expression in articular chondrocytes through formation of Gli3R.α-catenin.β-catenin ternary complex.

Rhee J, Ryu JH, Kim JH, Chun CH, Chun JS.

J Biol Chem. 2012 Apr 6;287(15):11751-60. doi: 10.1074/jbc.M111.281014. Epub 2012 Feb 1.

PMID:
22298781
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage.

Wu Q, Huang JH, Sampson ER, Kim KO, Zuscik MJ, O'Keefe RJ, Chen D, Rosier RN.

Exp Cell Res. 2009 Aug 15;315(14):2386-98. doi: 10.1016/j.yexcr.2009.05.019. Epub 2009 May 27.

PMID:
19481076
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Aberrant chondrocyte hypertrophy and activation of β-catenin signaling precede joint ankylosis in ank/ank mice.

Las Heras F, Pritzker KP, So A, Tsui HW, Chiu B, Inman RD, Tsui FW.

J Rheumatol. 2012 Mar;39(3):583-93. doi: 10.3899/jrheum.110971. Epub 2012 Feb 1.

PMID:
22298904
[PubMed - indexed for MEDLINE]
8.

Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms.

Hwang SG, Ryu JH, Kim IC, Jho EH, Jung HC, Kim K, Kim SJ, Chun JS.

J Biol Chem. 2004 Jun 18;279(25):26597-604. Epub 2004 Apr 13.

PMID:
15082716
[PubMed - indexed for MEDLINE]
Free Article
9.

Chondrocyte death during murine osteoarthritis.

Mistry D, Oue Y, Chambers MG, Kayser MV, Mason RM.

Osteoarthritis Cartilage. 2004 Feb;12(2):131-41.

PMID:
14723872
[PubMed - indexed for MEDLINE]
Free Article
10.

[Expression of beta-catenin in articular cartilage of knee primary osteoarthritis].

Fang X, Shi X, Gao Z, Bao L, Wang S, Jin Q.

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2012 May;26(5):532-5. Chinese.

PMID:
22702043
[PubMed - indexed for MEDLINE]
11.

Wnt/beta-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration.

Yuasa T, Otani T, Koike T, Iwamoto M, Enomoto-Iwamoto M.

Lab Invest. 2008 Mar;88(3):264-74. doi: 10.1038/labinvest.3700747. Epub 2008 Jan 28.

PMID:
18227807
[PubMed - indexed for MEDLINE]
Free Article
12.

Dual function of β-catenin in articular cartilage growth and degeneration at different stages of postnatal cartilage development.

Ning B, Wang P, Pei X, Kang Y, Song J, Wang D, Zhang W, Ma R.

Int Orthop. 2012 Mar;36(3):655-64. doi: 10.1007/s00264-011-1315-6. Epub 2011 Jul 14.

PMID:
21755332
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Transient activation of Wnt/{beta}-catenin signaling induces abnormal growth plate closure and articular cartilage thickening in postnatal mice.

Yuasa T, Kondo N, Yasuhara R, Shimono K, Mackem S, Pacifici M, Iwamoto M, Enomoto-Iwamoto M.

Am J Pathol. 2009 Nov;175(5):1993-2003. doi: 10.2353/ajpath.2009.081173. Epub 2009 Oct 8.

PMID:
19815716
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Roles of β-catenin signaling in phenotypic expression and proliferation of articular cartilage superficial zone cells.

Yasuhara R, Ohta Y, Yuasa T, Kondo N, Hoang T, Addya S, Fortina P, Pacifici M, Iwamoto M, Enomoto-Iwamoto M.

Lab Invest. 2011 Dec;91(12):1739-52. doi: 10.1038/labinvest.2011.144. Epub 2011 Oct 3.

PMID:
21968810
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Control of Dkk-1 ameliorates chondrocyte apoptosis, cartilage destruction, and subchondral bone deterioration in osteoarthritic knees.

Weng LH, Wang CJ, Ko JY, Sun YC, Wang FS.

Arthritis Rheum. 2010 May;62(5):1393-402. doi: 10.1002/art.27357.

PMID:
20131282
[PubMed - indexed for MEDLINE]
Free Article
16.

Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis.

Salminen H, Vuorio E, Säämänen AM.

Arthritis Rheum. 2001 Apr;44(4):947-55.

PMID:
11315934
[PubMed - indexed for MEDLINE]
Free Article
17.

A Wnt/β-catenin negative feedback loop inhibits interleukin-1-induced matrix metalloproteinase expression in human articular chondrocytes.

Ma B, van Blitterswijk CA, Karperien M.

Arthritis Rheum. 2012 Aug;64(8):2589-600. doi: 10.1002/art.34425.

PMID:
22328140
[PubMed - indexed for MEDLINE]
Free Article
18.

CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes.

Itoh S, Hattori T, Tomita N, Aoyama E, Yutani Y, Yamashiro T, Takigawa M.

PLoS One. 2013 Aug 12;8(8):e71156. doi: 10.1371/journal.pone.0071156. eCollection 2013.

PMID:
23951098
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Dkk-1 expression in chondrocytes inhibits experimental osteoarthritic cartilage destruction in mice.

Oh H, Chun CH, Chun JS.

Arthritis Rheum. 2012 Aug;64(8):2568-78. doi: 10.1002/art.34481.

PMID:
22488261
[PubMed - indexed for MEDLINE]
Free Article
20.

ICAT expression disrupts beta-catenin-TCF interactions and impairs survival of thymocytes and activated mature T cells.

Hossain MZ, Yu Q, Xu M, Sen JM.

Int Immunol. 2008 Jul;20(7):925-35. doi: 10.1093/intimm/dxn051. Epub 2008 May 28.

PMID:
18511409
[PubMed - indexed for MEDLINE]
Free PMC Article

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