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Items: 1 to 20 of 107

1.

Sphingomyelin synthase 2 deficiency attenuates NFkappaB activation.

Hailemariam TK, Huan C, Liu J, Li Z, Roman C, Kalbfeisch M, Bui HH, Peake DA, Kuo MS, Cao G, Wadgaonkar R, Jiang XC.

Arterioscler Thromb Vasc Biol. 2008 Aug;28(8):1519-26. doi: 10.1161/ATVBAHA.108.168682. Epub 2008 Jun 19.

2.

SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis.

Ding T, Li Z, Hailemariam T, Mukherjee S, Maxfield FR, Wu MP, Jiang XC.

J Lipid Res. 2008 Feb;49(2):376-85. Epub 2007 Nov 2.

3.

[Sphingomyelin synthase 2 deficiency decreases atherosclerosis and inhibits inflammation in mice].

Qin R, Chen ML, Zhu K, Deng JB, Shi YY.

Sheng Li Xue Bao. 2010 Aug 25;62(4):333-8. Chinese.

4.

Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.

Li Z, Hailemariam TK, Zhou H, Li Y, Duckworth DC, Peake DA, Zhang Y, Kuo MS, Cao G, Jiang XC.

Biochim Biophys Acta. 2007 Sep;1771(9):1186-94. Epub 2007 Jun 6.

5.

Sphingomyelin synthase 2 is one of the determinants for plasma and liver sphingomyelin levels in mice.

Liu J, Zhang H, Li Z, Hailemariam TK, Chakraborty M, Jiang K, Qiu D, Bui HH, Peake DA, Kuo MS, Wadgaonkar R, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):850-6. doi: 10.1161/ATVBAHA.109.185223. Epub 2009 Mar 12.

6.

Sphingomyelin synthase 2 (SMS2) deficiency attenuates LPS-induced lung injury.

Gowda S, Yeang C, Wadgaonkar S, Anjum F, Grinkina N, Cutaia M, Jiang XC, Wadgaonkar R.

Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L430-40. doi: 10.1152/ajplung.00208.2010. Epub 2010 Dec 29.

7.

Macrophage sphingomyelin synthase 2 deficiency decreases atherosclerosis in mice.

Liu J, Huan C, Chakraborty M, Zhang H, Lu D, Kuo MS, Cao G, Jiang XC.

Circ Res. 2009 Jul 31;105(3):295-303. doi: 10.1161/CIRCRESAHA.109.194613. Epub 2009 Jul 9.

8.

Dynamic modification of sphingomyelin in lipid microdomains controls development of obesity, fatty liver, and type 2 diabetes.

Mitsutake S, Zama K, Yokota H, Yoshida T, Tanaka M, Mitsui M, Ikawa M, Okabe M, Tanaka Y, Yamashita T, Takemoto H, Okazaki T, Watanabe K, Igarashi Y.

J Biol Chem. 2011 Aug 12;286(32):28544-55. doi: 10.1074/jbc.M111.255646. Epub 2011 Jun 13.

9.

Both sphingomyelin synthases SMS1 and SMS2 are required for sphingomyelin homeostasis and growth in human HeLa cells.

Tafesse FG, Huitema K, Hermansson M, van der Poel S, van den Dikkenberg J, Uphoff A, Somerharju P, Holthuis JC.

J Biol Chem. 2007 Jun 15;282(24):17537-47. Epub 2007 Apr 22.

10.

Impact of sphingomyelin synthase 1 deficiency on sphingolipid metabolism and atherosclerosis in mice.

Li Z, Fan Y, Liu J, Li Y, Huan C, Bui HH, Kuo MS, Park TS, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1577-84. doi: 10.1161/ATVBAHA.112.251538. Epub 2012 May 10.

11.

Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice.

Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC.

J Lipid Res. 2006 Jun;47(6):1307-14. Epub 2006 Feb 28.

12.

Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury.

Anjum F, Joshi K, Grinkina N, Gowda S, Cutaia M, Wadgaonkar R.

Am J Respir Cell Mol Biol. 2012 Jul;47(1):94-103. doi: 10.1165/rcmb.2010-0458OC. Epub 2012 Feb 23.

PMID:
22362386
13.

Sphingomyelin synthases regulate production of diacylglycerol at the Golgi.

Villani M, Subathra M, Im YB, Choi Y, Signorelli P, Del Poeta M, Luberto C.

Biochem J. 2008 Aug 15;414(1):31-41. doi: 10.1042/BJ20071240.

PMID:
18370930
14.

Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression.

Li Y, Dong J, Ding T, Kuo MS, Cao G, Jiang XC, Li Z.

Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1513-20. doi: 10.1161/ATVBAHA.113.301498. Epub 2013 May 2.

15.

Sphingomyelin synthase 2, but not sphingomyelin synthase 1, is involved in HIV-1 envelope-mediated membrane fusion.

Hayashi Y, Nemoto-Sasaki Y, Tanikawa T, Oka S, Tsuchiya K, Zama K, Mitsutake S, Sugiura T, Yamashita A.

J Biol Chem. 2014 Oct 31;289(44):30842-56. doi: 10.1074/jbc.M114.574285. Epub 2014 Sep 17.

16.

Adenovirus-mediated sphingomyelin synthase 2 increases atherosclerotic lesions in ApoE KO mice.

Wang X, Dong J, Zhao Y, Li Y, Wu M.

Lipids Health Dis. 2011 Jan 17;10:7. doi: 10.1186/1476-511X-10-7.

17.
18.

Tetraspanin CD9 negatively regulates lipopolysaccharide-induced macrophage activation and lung inflammation.

Suzuki M, Tachibana I, Takeda Y, He P, Minami S, Iwasaki T, Kida H, Goya S, Kijima T, Yoshida M, Kumagai T, Osaki T, Kawase I.

J Immunol. 2009 May 15;182(10):6485-93. doi: 10.4049/jimmunol.0802797.

19.

Selective reduction in the sphingomyelin content of atherogenic lipoproteins inhibits their retention in murine aortas and the subsequent development of atherosclerosis.

Fan Y, Shi F, Liu J, Dong J, Bui HH, Peake DA, Kuo MS, Cao G, Jiang XC.

Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2114-20. doi: 10.1161/ATVBAHA.110.213363. Epub 2010 Sep 2.

20.

Role of membrane sphingomyelin and ceramide in platform formation for Fas-mediated apoptosis.

Miyaji M, Jin ZX, Yamaoka S, Amakawa R, Fukuhara S, Sato SB, Kobayashi T, Domae N, Mimori T, Bloom ET, Okazaki T, Umehara H.

J Exp Med. 2005 Jul 18;202(2):249-59. Epub 2005 Jul 11.

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