Similar articles for PMID: 18551044

Year	Number of Results
1983	1
1984	2
1986	2
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1988	1
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1994	1
1995	1
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1998	1
2000	1
2002	2
2003	2
2004	2
2005	2
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2007	9
2008	18
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2010	7
2011	8
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2013	11
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2015	13
2016	11
2017	8
2018	11
2019	4
2020	5
2021	4
2022	5
2023	4
2024	0

1

OCT2 polymorphisms and in-vivo renal functional consequence: studies with metformin and cimetidine.

Wang ZJ, Yin OQ, Tomlinson B, Chow MS. Wang ZJ, et al. Pharmacogenet Genomics. 2008 Jul;18(7):637-45. doi: 10.1097/FPC.0b013e328302cd41. Pharmacogenet Genomics. 2008. PMID: 18551044

2

Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.

Zolk O, Solbach TF, König J, Fromm MF. Zolk O, et al. Drug Metab Dispos. 2009 Jun;37(6):1312-8. doi: 10.1124/dmd.108.023762. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251820

3

Genetic variants of the organic cation transporter 2 influence the disposition of metformin.

Song IS, Shin HJ, Shim EJ, Jung IS, Kim WY, Shon JH, Shin JG. Song IS, et al. Clin Pharmacol Ther. 2008 Nov;84(5):559-62. doi: 10.1038/clpt.2008.61. Epub 2008 Apr 9. Clin Pharmacol Ther. 2008. PMID: 18401339 Clinical Trial.

4

A gene-gene interaction between polymorphisms in the OCT2 and MATE1 genes influences the renal clearance of metformin.

Christensen MM, Pedersen RS, Stage TB, Brasch-Andersen C, Nielsen F, Damkier P, Beck-Nielsen H, Brøsen K. Christensen MM, et al. Pharmacogenet Genomics. 2013 Oct;23(10):526-34. doi: 10.1097/FPC.0b013e328364a57d. Pharmacogenet Genomics. 2013. PMID: 23873119 Clinical Trial.

5

Competitive inhibition of the luminal efflux by multidrug and toxin extrusions, but not basolateral uptake by organic cation transporter 2, is the likely mechanism underlying the pharmacokinetic drug-drug interactions caused by cimetidine in the kidney.

Ito S, Kusuhara H, Yokochi M, Toyoshima J, Inoue K, Yuasa H, Sugiyama Y. Ito S, et al. J Pharmacol Exp Ther. 2012 Feb;340(2):393-403. doi: 10.1124/jpet.111.184986. Epub 2011 Nov 9. J Pharmacol Exp Ther. 2012. PMID: 22072731

6

Effect of genetic variation in the organic cation transporter 2 on the renal elimination of metformin.

Chen Y, Li S, Brown C, Cheatham S, Castro RA, Leabman MK, Urban TJ, Chen L, Yee SW, Choi JH, Huang Y, Brett CM, Burchard EG, Giacomini KM. Chen Y, et al. Pharmacogenet Genomics. 2009 Jul;19(7):497-504. doi: 10.1097/FPC.0b013e32832cc7e9. Pharmacogenet Genomics. 2009. PMID: 19483665 Free PMC article. Clinical Trial.

7

High-resolution melting analysis for the rapid detection of an intronic single nucleotide polymorphism in SLC22A12 in male patients with primary gout in China.

Guan M, Zhang J, Chen Y, Liu W, Kong N, Zou H. Guan M, et al. Scand J Rheumatol. 2009;38(4):276-81. doi: 10.1080/03009740802572483. Scand J Rheumatol. 2009. PMID: 19306160

8

The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.

Cho SK, Chung JY. Cho SK, et al. Int J Clin Pharmacol Ther. 2016 Apr;54(4):253-62. doi: 10.5414/CP202473. Int J Clin Pharmacol Ther. 2016. PMID: 26784938

9

Polymorphism of organic cation transporter 2 improves glucose-lowering effect of metformin via influencing its pharmacokinetics in Chinese type 2 diabetic patients.

Hou W, Zhang D, Lu W, Zheng T, Wan L, Li Q, Bao Y, Liu F, Jia W. Hou W, et al. Mol Diagn Ther. 2015 Feb;19(1):25-33. doi: 10.1007/s40291-014-0126-z. Mol Diagn Ther. 2015. PMID: 25573751 Clinical Trial.

10

Metformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug-drug interactions.

Burt HJ, Neuhoff S, Almond L, Gaohua L, Harwood MD, Jamei M, Rostami-Hodjegan A, Tucker GT, Rowland-Yeo K. Burt HJ, et al. Eur J Pharm Sci. 2016 Jun 10;88:70-82. doi: 10.1016/j.ejps.2016.03.020. Epub 2016 Mar 25. Eur J Pharm Sci. 2016. PMID: 27019345 Free article.

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