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Results: 1 to 20 of 905

1.
2.

Activation of Bak and Bax through c-abl-protein kinase Cdelta-p38 MAPK signaling in response to ionizing radiation in human non-small cell lung cancer cells.

Choi SY, Kim MJ, Kang CM, Bae S, Cho CK, Soh JW, Kim JH, Kang S, Chung HY, Lee YS, Lee SJ.

J Biol Chem. 2006 Mar 17;281(11):7049-59. Epub 2006 Jan 12.

PMID:
16410245
[PubMed - indexed for MEDLINE]
Free Article
3.

Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak.

Tomiyama A, Serizawa S, Tachibana K, Sakurada K, Samejima H, Kuchino Y, Kitanaka C.

J Natl Cancer Inst. 2006 Oct 18;98(20):1462-73.

PMID:
17047195
[PubMed - indexed for MEDLINE]
Free Article
4.

Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.

Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.

Cancer Res. 2003 Apr 1;63(7):1712-21.

PMID:
12670926
[PubMed - indexed for MEDLINE]
Free Article
5.

Ionizing radiation utilizes c-Jun N-terminal kinase for amplification of mitochondrial apoptotic cell death in human cervical cancer cells.

Kim MJ, Lee KH, Lee SJ.

FEBS J. 2008 May;275(9):2096-108. doi: 10.1111/j.1742-4658.2008.06363.x. Epub 2008 Mar 28.

PMID:
18373696
[PubMed - indexed for MEDLINE]
6.

A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.

de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, Ripoche H, Lazar V, Dessen P, Harper F, Pierron G, Pinna G, Araujo N, Harel-Belan A, Armand JP, Wong TW, Soria JC, Kroemer G.

Cancer Res. 2007 Jul 1;67(13):6253-62.

PMID:
17616683
[PubMed - indexed for MEDLINE]
Free Article
7.

Caspase-2 triggers Bax-Bak-dependent and -independent cell death in colon cancer cells treated with resveratrol.

Mohan J, Gandhi AA, Bhavya BC, Rashmi R, Karunagaran D, Indu R, Santhoshkumar TR.

J Biol Chem. 2006 Jun 30;281(26):17599-611. Epub 2006 Apr 14.

PMID:
16617056
[PubMed - indexed for MEDLINE]
Free Article
9.

Erlotinib activates mitochondrial death pathways related to the production of reactive oxygen species in the human non-small cell lung cancer cell line A549.

Qian X, Li J, Ding J, Wang Z, Zhang W, Hu G.

Clin Exp Pharmacol Physiol. 2009 May;36(5-6):487-94. doi: 10.1111/j.1440-1681.2008.05091.x. Epub 2008 Oct 8.

PMID:
19673930
[PubMed - indexed for MEDLINE]
10.

Farnesyltransferase inhibitor BMS-214662 induces apoptosis in myeloma cells through PUMA up-regulation, Bax and Bak activation, and Mcl-1 elimination.

Gómez-Benito M, Marzo I, Anel A, Naval J.

Mol Pharmacol. 2005 Jun;67(6):1991-8. Epub 2005 Feb 28.

PMID:
15738311
[PubMed - indexed for MEDLINE]
Free Article
11.

Indirect effects of Bax and Bak initiate the mitochondrial alterations that lead to cytochrome c release during arsenic trioxide-induced apoptosis.

Nutt LK, Gogvadze V, Uthaisang W, Mirnikjoo B, McConkey DJ, Orrenius S.

Cancer Biol Ther. 2005 Apr;4(4):459-67. Epub 2005 Apr 28.

PMID:
15846091
[PubMed - indexed for MEDLINE]
Free Article
12.

Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cells.

Ling YH, Liebes L, Zou Y, Perez-Soler R.

J Biol Chem. 2003 Sep 5;278(36):33714-23. Epub 2003 Jun 23.

PMID:
12821677
[PubMed - indexed for MEDLINE]
Free Article
13.

The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.

Sung ES, Park KJ, Choi HJ, Kim CH, Kim YS.

Exp Cell Res. 2012 Aug 1;318(13):1564-76. doi: 10.1016/j.yexcr.2012.04.003. Epub 2012 Apr 10.

PMID:
22513214
[PubMed - indexed for MEDLINE]
14.

Helicobacter pylori vacuolating cytotoxin induces activation of the proapoptotic proteins Bax and Bak, leading to cytochrome c release and cell death, independent of vacuolation.

Yamasaki E, Wada A, Kumatori A, Nakagawa I, Funao J, Nakayama M, Hisatsune J, Kimura M, Moss J, Hirayama T.

J Biol Chem. 2006 Apr 21;281(16):11250-9. Epub 2006 Jan 25.

PMID:
16436379
[PubMed - indexed for MEDLINE]
Free Article
15.

Activation of Lck is critically required for sphingosine-induced conformational activation of Bak and mitochondrial cell death.

Kim MJ, Park MT, Yoon CH, Byun JY, Lee SJ.

Biochem Biophys Res Commun. 2008 May 30;370(2):353-8. doi: 10.1016/j.bbrc.2008.03.084. Epub 2008 Mar 25.

PMID:
18371298
[PubMed - indexed for MEDLINE]
16.

Resveratrol induces apoptosis via a Bak-mediated intrinsic pathway in human lung adenocarcinoma cells.

Zhang W, Wang X, Chen T.

Cell Signal. 2012 May;24(5):1037-46. doi: 10.1016/j.cellsig.2011.12.025. Epub 2012 Jan 5.

PMID:
22245142
[PubMed - indexed for MEDLINE]
17.

Subtilase cytotoxin induces apoptosis in HeLa cells by mitochondrial permeabilization via activation of Bax/Bak, independent of C/EBF-homologue protein (CHOP), Ire1alpha or JNK signaling.

Yahiro K, Morinaga N, Moss J, Noda M.

Microb Pathog. 2010 Oct;49(4):153-63. doi: 10.1016/j.micpath.2010.05.007. Epub 2010 Jun 2.

PMID:
20561923
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Phytosphingosine induces apoptotic cell death via caspase 8 activation and Bax translocation in human cancer cells.

Park MT, Kang JA, Choi JA, Kang CM, Kim TH, Bae S, Kang S, Kim S, Choi WI, Cho CK, Chung HY, Lee YS, Lee SJ.

Clin Cancer Res. 2003 Feb;9(2):878-85.

PMID:
12576463
[PubMed - indexed for MEDLINE]
Free Article

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