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Items: 1 to 20 of 127

1.

Bcl-2 family members: dual regulators of apoptosis and autophagy.

Levine B, Sinha S, Kroemer G.

Autophagy. 2008 Jul;4(5):600-6. Epub 2008 May 12. Review.

2.

BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L).

Maiuri MC, Criollo A, Tasdemir E, Vicencio JM, Tajeddine N, Hickman JA, Geneste O, Kroemer G.

Autophagy. 2007 Jul-Aug;3(4):374-6. Epub 2007 Jul 4.

PMID:
17438366
3.

Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome.

Salminen A, Kaarniranta K, Kauppinen A, Ojala J, Haapasalo A, Soininen H, Hiltunen M.

Prog Neurobiol. 2013 Jul-Aug;106-107:33-54. doi: 10.1016/j.pneurobio.2013.06.002. Epub 2013 Jul 1. Review.

PMID:
23827971
4.

BH3 mimetics reveal the network properties of autophagy-regulatory signaling cascades.

Malik SA, Shen S, Mariño G, BenYounès A, Maiuri MC, Kroemer G.

Autophagy. 2011 Aug;7(8):914-6. Epub 2011 Aug 1.

PMID:
21508685
5.

The Beclin 1 network regulates autophagy and apoptosis.

Kang R, Zeh HJ, Lotze MT, Tang D.

Cell Death Differ. 2011 Apr;18(4):571-80. doi: 10.1038/cdd.2010.191. Epub 2011 Feb 11. Review.

6.

Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1.

Maiuri MC, Le Toumelin G, Criollo A, Rain JC, Gautier F, Juin P, Tasdemir E, Pierron G, Troulinaki K, Tavernarakis N, Hickman JA, Geneste O, Kroemer G.

EMBO J. 2007 May 16;26(10):2527-39. Epub 2007 Apr 19.

7.

The autophagy effector Beclin 1: a novel BH3-only protein.

Sinha S, Levine B.

Oncogene. 2008 Dec;27 Suppl 1:S137-48. doi: 10.1038/onc.2009.51. Review.

8.

Differential interactions between Beclin 1 and Bcl-2 family members.

Erlich S, Mizrachy L, Segev O, Lindenboim L, Zmira O, Adi-Harel S, Hirsch JA, Stein R, Pinkas-Kramarski R.

Autophagy. 2007 Nov-Dec;3(6):561-8. Epub 2007 Jul 8.

PMID:
17643073
9.

Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein.

Oberstein A, Jeffrey PD, Shi Y.

J Biol Chem. 2007 Apr 27;282(17):13123-32. Epub 2007 Mar 2.

10.

BH3-only proteins in apoptosis and beyond: an overview.

Lomonosova E, Chinnadurai G.

Oncogene. 2008 Dec;27 Suppl 1:S2-19. doi: 10.1038/onc.2009.39. Review.

11.

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy.

Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A.

EMBO Rep. 2009 Mar;10(3):285-92. doi: 10.1038/embor.2008.246. Epub 2009 Jan 30.

12.

Regulation of apoptosis by BH3 domains in a cell-free system.

Cosulich SC, Worrall V, Hedge PJ, Green S, Clarke PR.

Curr Biol. 1997 Dec 1;7(12):913-20.

13.

Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL.

Zalckvar E, Berissi H, Eisenstein M, Kimchi A.

Autophagy. 2009 Jul;5(5):720-2. Epub 2009 Jul 2.

PMID:
19395874
14.

Molecular basis of the regulation of Beclin 1-dependent autophagy by the gamma-herpesvirus 68 Bcl-2 homolog M11.

Sinha S, Colbert CL, Becker N, Wei Y, Levine B.

Autophagy. 2008 Nov;4(8):989-97. Epub 2008 Nov 18. Erratum in: Autophagy.2009 Feb;5(2):284.

15.

Beclin 1: a BH3-only protein that fails to induce apoptosis.

Boya P, Kroemer G.

Oncogene. 2009 May 28;28(21):2125-7. doi: 10.1038/onc.2009.83. Epub 2009 Apr 27.

PMID:
19398951
16.

BH3 mimetics activate multiple pro-autophagic pathways.

Malik SA, Orhon I, Morselli E, Criollo A, Shen S, Mariño G, BenYounes A, Bénit P, Rustin P, Maiuri MC, Kroemer G.

Oncogene. 2011 Sep 15;30(37):3918-29. doi: 10.1038/onc.2011.104. Epub 2011 Apr 4.

PMID:
21460857
18.

Proteins of the bcl-2 family in apoptosis signalling: from mechanistic insights to therapeutic opportunities.

Chan SL, Yu VC.

Clin Exp Pharmacol Physiol. 2004 Mar;31(3):119-28. Review.

PMID:
15008953
19.

Targeting γ-herpesvirus 68 Bcl-2-mediated down-regulation of autophagy.

Su M, Mei Y, Sanishvili R, Levine B, Colbert CL, Sinha S.

J Biol Chem. 2014 Mar 21;289(12):8029-40. doi: 10.1074/jbc.M113.515361. Epub 2014 Jan 17.

20.

Why doesn't Beclin 1, a BH3-only protein, suppress the anti-apoptotic function of Bcl-2?

Ciechomska IA, Goemans CG, Tolkovsky AM.

Autophagy. 2009 Aug;5(6):880-1. Epub 2009 Aug 22.

PMID:
19535901
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