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Results: 1 to 20 of 169

1.

Cooperative roles of c-Abl and Cdk5 in regulation of p53 in response to oxidative stress.

Lee JH, Jeong MW, Kim W, Choi YH, Kim KT.

J Biol Chem. 2008 Jul 11;283(28):19826-35. doi: 10.1074/jbc.M706201200. Epub 2008 May 19.

PMID:
18490454
[PubMed - indexed for MEDLINE]
Free Article
2.

Stabilization and activation of p53 induced by Cdk5 contributes to neuronal cell death.

Lee JH, Kim HS, Lee SJ, Kim KT.

J Cell Sci. 2007 Jul 1;120(Pt 13):2259-71.

PMID:
17591690
[PubMed - indexed for MEDLINE]
Free Article
3.

c-Abl phosphorylates Hdm2 at tyrosine 276 in response to DNA damage and regulates interaction with ARF.

Dias SS, Milne DM, Meek DW.

Oncogene. 2006 Oct 26;25(50):6666-71. Epub 2006 May 15.

PMID:
16702947
[PubMed - indexed for MEDLINE]
4.

Abl deregulates Cdk5 kinase activity and subcellular localization in Drosophila neurodegeneration.

Lin H, Lin TY, Juang JL.

Cell Death Differ. 2007 Mar;14(3):607-15. Epub 2006 Aug 25.

PMID:
16932754
[PubMed - indexed for MEDLINE]
Free Article
5.

c-Abl regulates p53 levels under normal and stress conditions by preventing its nuclear export and ubiquitination.

Sionov RV, Coen S, Goldberg Z, Berger M, Bercovich B, Ben-Neriah Y, Ciechanover A, Haupt Y.

Mol Cell Biol. 2001 Sep;21(17):5869-78.

PMID:
11486026
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

c-Abl neutralizes the inhibitory effect of Mdm2 on p53.

Sionov RV, Moallem E, Berger M, Kazaz A, Gerlitz O, Ben-Neriah Y, Oren M, Haupt Y.

J Biol Chem. 1999 Mar 26;274(13):8371-4.

PMID:
10085066
[PubMed - indexed for MEDLINE]
Free Article
7.

Regulation of cyclin-dependent kinase 5 and p53 by ERK1/2 pathway in the DNA damage-induced neuronal death.

Lee JH, Kim KT.

J Cell Physiol. 2007 Mar;210(3):784-97.

PMID:
17117479
[PubMed - indexed for MEDLINE]
8.

Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.

Goldberg Z, Vogt Sionov R, Berger M, Zwang Y, Perets R, Van Etten RA, Oren M, Taya Y, Haupt Y.

EMBO J. 2002 Jul 15;21(14):3715-27.

PMID:
12110584
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Enterovirus 71 triggering of neuronal apoptosis through activation of Abl-Cdk5 signalling.

Chen TC, Lai YK, Yu CK, Juang JL.

Cell Microbiol. 2007 Nov;9(11):2676-88. Epub 2007 Jun 20.

PMID:
17581253
[PubMed - indexed for MEDLINE]
10.

A nestin scaffold links Cdk5/p35 signaling to oxidant-induced cell death.

Sahlgren CM, Pallari HM, He T, Chou YH, Goldman RD, Eriksson JE.

EMBO J. 2006 Oct 18;25(20):4808-19. Epub 2006 Oct 12.

PMID:
17036052
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

c-Abl phosphorylates Hdmx and regulates its interaction with p53.

Zuckerman V, Lenos K, Popowicz GM, Silberman I, Grossman T, Marine JC, Holak TA, Jochemsen AG, Haupt Y.

J Biol Chem. 2009 Feb 6;284(6):4031-9. doi: 10.1074/jbc.M809211200. Epub 2008 Dec 15.

PMID:
19075013
[PubMed - indexed for MEDLINE]
Free Article
12.

The oncoprotein SS18-SSX1 promotes p53 ubiquitination and degradation by enhancing HDM2 stability.

D'Arcy P, Maruwge W, Ryan BA, Brodin B.

Mol Cancer Res. 2008 Jan;6(1):127-38. doi: 10.1158/1541-7786.MCR-07-0176.

PMID:
18234968
[PubMed - indexed for MEDLINE]
Free Article
13.

C-Abl as a modulator of p53.

Levav-Cohen Y, Goldberg Z, Zuckerman V, Grossman T, Haupt S, Haupt Y.

Biochem Biophys Res Commun. 2005 Jun 10;331(3):737-49. Review.

PMID:
15865930
[PubMed - indexed for MEDLINE]
14.

Nuclear accumulations of p53 and Mdm2 are accompanied by reductions in c-Abl and p300 in zinc-depleted human hepatoblastoma cells.

Alshatwi AA, Han CT, Schoene NW, Lei KY.

Exp Biol Med (Maywood). 2006 May;231(5):611-8.

PMID:
16636310
[PubMed - indexed for MEDLINE]
15.

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation.

Stommel JM, Wahl GM.

Cell Cycle. 2005 Mar;4(3):411-7. Epub 2005 Mar 2. Review.

PMID:
15684615
[PubMed - indexed for MEDLINE]
Free Article
16.

Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease.

Imam SZ, Zhou Q, Yamamoto A, Valente AJ, Ali SF, Bains M, Roberts JL, Kahle PJ, Clark RA, Li S.

J Neurosci. 2011 Jan 5;31(1):157-63. doi: 10.1523/JNEUROSCI.1833-10.2011.

PMID:
21209200
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

DNA mismatch repair-dependent activation of c-Abl/p73alpha/GADD45alpha-mediated apoptosis.

Li LS, Morales JC, Hwang A, Wagner MW, Boothman DA.

J Biol Chem. 2008 Aug 1;283(31):21394-403. doi: 10.1074/jbc.M709954200. Epub 2008 May 14.

PMID:
18480060
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells.

Yang Y, Ludwig RL, Jensen JP, Pierre SA, Medaglia MV, Davydov IV, Safiran YJ, Oberoi P, Kenten JH, Phillips AC, Weissman AM, Vousden KH.

Cancer Cell. 2005 Jun;7(6):547-59.

PMID:
15950904
[PubMed - indexed for MEDLINE]
Free Article
19.

Lyn tyrosine kinase inhibits nuclear export of the p53 tumor suppressor.

Ren X, Cao C, Zhu L, Yoshida K, Kharbanda S, Weichselbaum R, Kufe D.

Cancer Biol Ther. 2002 Nov-Dec;1(6):703-8.

PMID:
12642697
[PubMed - indexed for MEDLINE]
Free Article
20.

c-Abl tyrosine kinase selectively regulates p73 nuclear matrix association.

Ben-Yehoyada M, Ben-Dor I, Shaul Y.

J Biol Chem. 2003 Sep 5;278(36):34475-82. Epub 2003 Jun 24.

PMID:
12824179
[PubMed - indexed for MEDLINE]
Free Article

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