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Items: 1 to 20 of 247

1.

A novel selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis.

Bujalska IJ, Gathercole LL, Tomlinson JW, Darimont C, Ermolieff J, Fanjul AN, Rejto PA, Stewart PM.

J Endocrinol. 2008 May;197(2):297-307. doi: 10.1677/JOE-08-0050.

2.

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol.

Bujalska IJ, Walker EA, Tomlinson JW, Hewison M, Stewart PM.

Endocr Res. 2002 Nov;28(4):449-61.

PMID:
12530648
3.

The environmental obesogen bisphenol A promotes adipogenesis by increasing the amount of 11β-hydroxysteroid dehydrogenase type 1 in the adipose tissue of children.

Wang J, Sun B, Hou M, Pan X, Li X.

Int J Obes (Lond). 2013 Jul;37(7):999-1005. doi: 10.1038/ijo.2012.173. Epub 2012 Oct 23.

PMID:
23090578
5.

Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake.

McNelis JC, Manolopoulos KN, Gathercole LL, Bujalska IJ, Stewart PM, Tomlinson JW, Arlt W.

Am J Physiol Endocrinol Metab. 2013 Nov 1;305(9):E1134-44. doi: 10.1152/ajpendo.00314.2012. Epub 2013 Sep 10.

6.

The role of 11beta-hydroxysteroid dehydrogenase 1 in adipogenesis in thyroid-associated ophthalmopathy.

Tomlinson JW, Durrani OM, Bujalska IJ, Gathercole LL, Tomlins PJ, Reuser TT, Rose GE, Curnow SJ, Stewart PM, Walker EA, Rauz S.

J Clin Endocrinol Metab. 2010 Jan;95(1):398-406. doi: 10.1210/jc.2009-0873. Epub 2009 Oct 30.

PMID:
19880789
7.
8.

Preadipocyte 11beta-hydroxysteroid dehydrogenase type 1 is a keto-reductase and contributes to diet-induced visceral obesity in vivo.

De Sousa Peixoto RA, Turban S, Battle JH, Chapman KE, Seckl JR, Morton NM.

Endocrinology. 2008 Apr;149(4):1861-8. doi: 10.1210/en.2007-1028. Epub 2008 Jan 3.

PMID:
18174284
9.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor in the diet-induced obese mice.

Park JS, Rhee SD, Jung WH, Kang NS, Kim HY, Kang SK, Ahn JH, Kim KY.

Eur J Pharmacol. 2012 Sep 15;691(1-3):19-27. doi: 10.1016/j.ejphar.2012.06.024. Epub 2012 Jul 1.

PMID:
22760069
10.

Characterisation of 11beta-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat.

Bujalska IJ, Durrani OM, Abbott J, Onyimba CU, Khosla P, Moosavi AH, Reuser TT, Stewart PM, Tomlinson JW, Walker EA, Rauz S.

J Endocrinol. 2007 Feb;192(2):279-88.

11.

Expression of 11beta-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity.

Tomlinson JW, Sinha B, Bujalska I, Hewison M, Stewart PM.

J Clin Endocrinol Metab. 2002 Dec;87(12):5630-5.

PMID:
12466364
12.

Suppression of 11beta-hydroxysteroid dehydrogenase type 1 with RNA interference substantially attenuates 3T3-L1 adipogenesis.

Liu Y, Park F, Pietrusz JL, Jia G, Singh RJ, Netzel BC, Liang M.

Physiol Genomics. 2008 Feb 19;32(3):343-51. Epub 2007 Dec 11.

14.

Characterisation of the prereceptor regulation of glucocorticoids in the anterior segment of the rabbit eye.

Onyimba CU, Vijapurapu N, Curnow SJ, Khosla P, Stewart PM, Murray PI, Walker EA, Rauz S.

J Endocrinol. 2006 Aug;190(2):483-93.

15.

11beta-hydroxysteroid dehydrogenase type 1 and obesity.

Morton NM, Seckl JR.

Front Horm Res. 2008;36:146-64. doi: 10.1159/0000115363. Review.

PMID:
18230901
16.

Inhibitors of 11β-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy.

Wang M.

Handb Exp Pharmacol. 2011;(203):127-46. doi: 10.1007/978-3-642-17214-4_6. Review.

PMID:
21484570
17.

Glucocorticoids and 11beta-hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome.

Stimson RH, Walker BR.

Minerva Endocrinol. 2007 Sep;32(3):141-59. Review.

PMID:
17912154
18.

Anti-diabetic and anti-adipogenic effects of a novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor, 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344).

Park JS, Rhee SD, Kang NS, Jung WH, Kim HY, Kim JH, Kang SK, Cheon HG, Ahn JH, Kim KY.

Biochem Pharmacol. 2011 Apr 15;81(8):1028-35. doi: 10.1016/j.bcp.2011.01.020. Epub 2011 Feb 18.

PMID:
21315688
19.

Differential modulation of 3T3-L1 adipogenesis mediated by 11beta-hydroxysteroid dehydrogenase-1 levels.

Kim J, Temple KA, Jones SA, Meredith KN, Basko JL, Brady MJ.

J Biol Chem. 2007 Apr 13;282(15):11038-46. Epub 2007 Feb 20.

20.

Osteoblastic 11beta-hydroxysteroid dehydrogenase type 1 activity increases with age and glucocorticoid exposure.

Cooper MS, Rabbitt EH, Goddard PE, Bartlett WA, Hewison M, Stewart PM.

J Bone Miner Res. 2002 Jun;17(6):979-86.

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