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Significantly improved accuracy of diagnosis of early Lyme disease by peptide enzyme-linked immunosorbent assay based on the borreliacidal antibody epitope of Borrelia burgdorferi OspC.

Jobe DA, Lovrich SD, Asp KE, Mathiason MA, Albrecht SE, Schell RF, Callister SM.

Clin Vaccine Immunol. 2008 Jun;15(6):981-5. doi: 10.1128/CVI.00079-08. Epub 2008 Apr 16.


Borreliacidal OspC antibodies specific for a highly conserved epitope are immunodominant in human lyme disease and do not occur in mice or hamsters.

Lovrich SD, Jobe DA, Schell RF, Callister SM.

Clin Diagn Lab Immunol. 2005 Jun;12(6):746-51. Erratum in: Clin Diagn Lab Immunol. 2005 Sep;12(9):1139.


C-terminal region of outer surface protein C binds borreliacidal antibodies in sera from patients with Lyme disease.

Jobe DA, Lovrich SD, Schell RF, Callister SM.

Clin Diagn Lab Immunol. 2003 Jul;10(4):573-8.


Specific immune response to a synthetic peptide derived from outer surface protein C of Borrelia burgdorferi predicts protective borreliacidal antibodies.

Ikushima M, Matsui K, Yamada F, Kawahashi S, Nishikawa SK.

FEMS Immunol Med Microbiol. 2000 Sep;29(1):15-21.


Outer surface protein C peptide derived from Borrelia burgdorferi sensu stricto as a target for serodiagnosis of early lyme disease.

Arnaboldi PM, Seedarnee R, Sambir M, Callister SM, Imparato JA, Dattwyler RJ.

Clin Vaccine Immunol. 2013 Apr;20(4):474-81. doi: 10.1128/CVI.00608-12. Epub 2013 Jan 30.


Rapid decline of OspC borreliacidal antibodies following treatment of patients with early Lyme disease.

Jobe DA, Kowalski TJ, Bloemke M, Lovrich SD, Callister SM.

Clin Vaccine Immunol. 2011 Jun;18(6):1034-7. doi: 10.1128/CVI.00063-11. Epub 2011 Apr 20.


Prospective study of serologic tests for lyme disease.

Steere AC, McHugh G, Damle N, Sikand VK.

Clin Infect Dis. 2008 Jul 15;47(2):188-95. doi: 10.1086/589242.


Borreliacidal OspC antibody response of canines with Lyme disease differs significantly from that of humans with Lyme disease.

Lovrich SD, La Fleur RL, Jobe DA, Johnson JC, Asp KE, Schell RF, Callister SM.

Clin Vaccine Immunol. 2007 May;14(5):635-7. Epub 2007 Mar 7.


Recombinant OspC from Borrelia burgdorferi sensu stricto, B. afzelii and B. garinii in the serodiagnosis of Lyme borreliosis.

Panelius J, Lahdenne P, Heikkilä T, Peltomaa M, Oksi J, Seppälä I.

J Med Microbiol. 2002 Sep;51(9):731-9.


Characterization of a unique borreliacidal epitope on the outer surface protein C of Borrelia burgdorferi.

Yang X, Li Y, Dunn JJ, Luft BJ.

FEMS Immunol Med Microbiol. 2006 Oct;48(1):64-74.


Borreliacidal antibody production against outer surface protein C of Borrelia burgdorferi.

Rousselle JC, Callister SM, Schell RF, Lovrich SD, Jobe DA, Marks JA, Wieneke CA.

J Infect Dis. 1998 Sep;178(3):733-41.


Bacterin that induces anti-OspA and anti-OspC borreliacidal antibodies provides a high level of protection against canine Lyme disease.

LaFleur RL, Dant JC, Wasmoen TL, Callister SM, Jobe DA, Lovrich SD, Warner TF, Abdelmagid O, Schell RF.

Clin Vaccine Immunol. 2009 Feb;16(2):253-9. doi: 10.1128/CVI.00373-08. Epub 2008 Dec 3.


Serologic diagnosis of Lyme borreliosis by using enzyme-linked immunosorbent assays with recombinant antigens.

Magnarelli LA, Ijdo JW, Padula SJ, Flavell RA, Fikrig E.

J Clin Microbiol. 2000 May;38(5):1735-9.


Comparative evaluation of two enzyme linked immunosorbent assay methods and three Western Blot methods for the diagnosis of culture-confirmed early Lyme borreliosis in Italy.

Marangoni A, Sparacino M, Mondardini V, Cavrini F, Storni E, Donati M, Cevenini R, Sambri V.

New Microbiol. 2005 Jan;28(1):37-43.

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