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Items: 1 to 20 of 113

1.

Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2.

Vidal R, Barbeito AG, Miravalle L, Ghetti B.

Brain Pathol. 2009 Jan;19(1):58-68. doi: 10.1111/j.1750-3639.2008.00164.x. Epub 2008 Apr 10.

2.

Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice.

Garringer HJ, Murrell J, Sammeta N, Gnezda A, Ghetti B, Vidal R.

PLoS One. 2013;8(2):e56426. doi: 10.1371/journal.pone.0056426. Epub 2013 Feb 13.

3.

Modeling familial British and Danish dementia.

Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R.

Brain Struct Funct. 2010 Mar;214(2-3):235-44. doi: 10.1007/s00429-009-0221-9. Epub 2009 Sep 25. Review.

PMID:
19779737
4.

Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta.

Holton JL, Lashley T, Ghiso J, Braendgaard H, Vidal R, Guerin CJ, Gibb G, Hanger DP, Rostagno A, Anderton BH, Strand C, Ayling H, Plant G, Frangione B, Bojsen-Møller M, Revesz T.

J Neuropathol Exp Neurol. 2002 Mar;61(3):254-67.

5.

Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis.

Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L.

J Neurosci. 2010 Nov 3;30(44):14915-24. doi: 10.1523/JNEUROSCI.3917-10.2010.

6.

Chromosome 13 dementias.

Rostagno A, Tomidokoro Y, Lashley T, Ng D, Plant G, Holton J, Frangione B, Revesz T, Ghiso J.

Cell Mol Life Sci. 2005 Aug;62(16):1814-25. Review.

PMID:
15968464
7.

Expression of BRI2 mRNA and protein in normal human brain and familial British dementia: its relevance to the pathogenesis of disease.

Lashley T, Revesz T, Plant G, Bandopadhyay R, Lees AJ, Frangione B, Wood NW, de Silva R, Ghiso J, Rostagno A, Holton JL.

Neuropathol Appl Neurobiol. 2008 Oct;34(5):492-505. doi: 10.1111/j.1365-2990.2008.00935.x. Epub 2008 Feb 13.

8.

Generation and initial characterization of FDD knock in mice.

Giliberto L, Matsuda S, Vidal R, D'Adamio L.

PLoS One. 2009 Nov 18;4(11):e7900. doi: 10.1371/journal.pone.0007900.

9.

Modeling familial British dementia in transgenic mice.

Pickford F, Coomaraswamy J, Jucker M, McGowan E.

Brain Pathol. 2006 Jan;16(1):80-5. Review.

PMID:
16612985
10.

APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant.

Tamayev R, Matsuda S, Giliberto L, Arancio O, D'Adamio L.

EMBO J. 2011 May 17;30(12):2501-9. doi: 10.1038/emboj.2011.161.

11.

Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits.

Tamayev R, Matsuda S, Fà M, Arancio O, D'Adamio L.

Proc Natl Acad Sci U S A. 2010 Nov 30;107(48):20822-7. doi: 10.1073/pnas.1011689107. Epub 2010 Nov 22.

12.

Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease.

Coomaraswamy J, Kilger E, Wölfing H, Schäfer C, Kaeser SA, Wegenast-Braun BM, Hefendehl JK, Wolburg H, Mazzella M, Ghiso J, Goedert M, Akiyama H, Garcia-Sierra F, Wolfer DP, Mathews PM, Jucker M.

Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7969-74. doi: 10.1073/pnas.1001056107. Epub 2010 Apr 12.

13.

Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia.

Marcora MS, Fernández-Gamba AC, Avendaño LA, Rotondaro C, Podhajcer OL, Vidal R, Morelli L, Ceriani MF, Castaño EM.

Mol Neurodegener. 2014 Jan 9;9:5. doi: 10.1186/1750-1326-9-5.

14.

Genetic alterations of the BRI2 gene: familial British and Danish dementias.

Ghiso J, Rostagno A, Tomidokoro Y, Lashley T, Bojsen-Møller M, Braendgaard H, Plant G, Holton J, Lal R, Revesz T, Frangione B.

Brain Pathol. 2006 Jan;16(1):71-9.

PMID:
16612984
15.

A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred.

Vidal R, Revesz T, Rostagno A, Kim E, Holton JL, Bek T, Bojsen-Møller M, Braendgaard H, Plant G, Ghiso J, Frangione B.

Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4920-5.

16.

Oligomerization and neurotoxicity of the amyloid ADan peptide implicated in familial Danish dementia.

Gibson G, Gunasekera N, Lee M, Lelyveld V, El-Agnaf OM, Wright A, Austen B.

J Neurochem. 2004 Jan;88(2):281-90.

17.

Early-onset formation of parenchymal plaque amyloid abrogates cerebral microvascular amyloid accumulation in transgenic mice.

Xu F, Kotarba AE, Ou-Yang MH, Fu Z, Davis J, Smith SO, Van Nostrand WE.

J Biol Chem. 2014 Jun 20;289(25):17895-908. doi: 10.1074/jbc.M113.536565. Epub 2014 May 14.

18.

Human apolipoprotein E2 promotes parenchymal amyloid deposition and neuronal loss in vasculotropic mutant amyloid-β protein Tg-SwDI mice.

Xu F, Vitek MP, Colton CA, Previti ML, Davis J, Van Nostrand WE.

J Alzheimers Dis. 2012;31(2):359-69. doi: 10.3233/JAD-2012-120421.

PMID:
22635103
19.

Preamyloid lesions and cerebrovascular deposits in the mechanism of dementia: lessons from non-beta-amyloid cerebral amyloidosis.

Rostagno A, Ghiso J.

Neurodegener Dis. 2008;5(3-4):173-5. doi: 10.1159/000113694. Epub 2008 Mar 6. Review.

20.

Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathies.

Revesz T, Holton JL, Lashley T, Plant G, Frangione B, Rostagno A, Ghiso J.

Acta Neuropathol. 2009 Jul;118(1):115-30. doi: 10.1007/s00401-009-0501-8. Epub 2009 Feb 19. Review. Erratum in: Acta Neuropathol. 2009 Aug;118(2):321.

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