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Results: 1 to 20 of 95

1.

Lesion processing: high-fidelity versus lesion-bypass DNA polymerases.

Broyde S, Wang L, Rechkoblit O, Geacintov NE, Patel DJ.

Trends Biochem Sci. 2008 May;33(5):209-19. doi: 10.1016/j.tibs.2008.02.004. Epub 2008 Apr 11. Review.

PMID:
18407502
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Kinetic basis for the differing response to an oxidative lesion by a replicative and a lesion bypass DNA polymerase from Sulfolobus solfataricus.

Maxwell BA, Suo Z.

Biochemistry. 2012 Apr 24;51(16):3485-96. doi: 10.1021/bi300246r. Epub 2012 Apr 10.

PMID:
22471521
[PubMed - indexed for MEDLINE]
3.

Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion.

Rechkoblit O, Malinina L, Cheng Y, Kuryavyi V, Broyde S, Geacintov NE, Patel DJ.

PLoS Biol. 2006 Jan;4(1):e11.

PMID:
16379496
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Evading the proofreading machinery of a replicative DNA polymerase: induction of a mutation by an environmental carcinogen.

Perlow RA, Broyde S.

J Mol Biol. 2001 Jun 1;309(2):519-36.

PMID:
11371169
[PubMed - indexed for MEDLINE]
5.

Impact of conformational heterogeneity of OxoG lesions and their pairing partners on bypass fidelity by Y family polymerases.

Rechkoblit O, Malinina L, Cheng Y, Geacintov NE, Broyde S, Patel DJ.

Structure. 2009 May 13;17(5):725-36. doi: 10.1016/j.str.2009.03.011.

PMID:
19446528
[PubMed - indexed for MEDLINE]
Free Article
7.

Sloppy bypass of an abasic lesion catalyzed by a Y-family DNA polymerase.

Fiala KA, Suo Z.

J Biol Chem. 2007 Mar 16;282(11):8199-206. Epub 2007 Jan 18.

PMID:
17234630
[PubMed - indexed for MEDLINE]
Free Article
8.
9.
10.

Extending the understanding of mutagenicity: structural insights into primer-extension past a benzo[a]pyrene diol epoxide-DNA adduct.

Perlow RA, Broyde S.

J Mol Biol. 2003 Apr 4;327(4):797-818.

PMID:
12654264
[PubMed - indexed for MEDLINE]
11.

Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4.

Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP.

J Biol Chem. 2006 Jan 27;281(4):2358-72. Epub 2005 Nov 22. Erratum in: J Biol Chem. 2008 May 9;283(19):13500.

PMID:
16306039
[PubMed - indexed for MEDLINE]
Free Article
12.

Increased flexibility enhances misincorporation: temperature effects on nucleotide incorporation opposite a bulky carcinogen-DNA adduct by a Y-family DNA polymerase.

Perlow-Poehnelt RA, Likhterov I, Wang L, Scicchitano DA, Geacintov NE, Broyde S.

J Biol Chem. 2007 Jan 12;282(2):1397-408. Epub 2006 Nov 6.

PMID:
17090533
[PubMed - indexed for MEDLINE]
Free Article
13.

Mechanism of abasic lesion bypass catalyzed by a Y-family DNA polymerase.

Fiala KA, Hypes CD, Suo Z.

J Biol Chem. 2007 Mar 16;282(11):8188-98. Epub 2007 Jan 8.

PMID:
17210571
[PubMed - indexed for MEDLINE]
Free Article
14.

Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4.

Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP.

J Biol Chem. 2007 Jul 6;282(27):19831-43. Epub 2007 Apr 27.

PMID:
17468100
[PubMed - indexed for MEDLINE]
Free Article
15.

A water-mediated and substrate-assisted catalytic mechanism for Sulfolobus solfataricus DNA polymerase IV.

Wang L, Yu X, Hu P, Broyde S, Zhang Y.

J Am Chem Soc. 2007 Apr 18;129(15):4731-7. Epub 2007 Mar 22.

PMID:
17375926
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The efficiency and specificity of apurinic/apyrimidinic site bypass by human DNA polymerase eta and Sulfolobus solfataricus Dpo4.

Kokoska RJ, McCulloch SD, Kunkel TA.

J Biol Chem. 2003 Dec 12;278(50):50537-45. Epub 2003 Sep 30.

PMID:
14523013
[PubMed - indexed for MEDLINE]
Free Article
17.

DNA lesion alters global conformational dynamics of Y-family DNA polymerase during catalysis.

Maxwell BA, Xu C, Suo Z.

J Biol Chem. 2012 Apr 13;287(16):13040-7. doi: 10.1074/jbc.M112.345835. Epub 2012 Feb 23.

PMID:
22362779
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase.

Sherrer SM, Brown JA, Pack LR, Jasti VP, Fowler JD, Basu AK, Suo Z.

J Biol Chem. 2009 Mar 6;284(10):6379-88. doi: 10.1074/jbc.M808161200. Epub 2009 Jan 5.

PMID:
19124465
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The N-clasp of human DNA polymerase kappa promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions.

Jia L, Geacintov NE, Broyde S.

Nucleic Acids Res. 2008 Nov;36(20):6571-84. doi: 10.1093/nar/gkn719. Epub 2008 Oct 17.

PMID:
18931375
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Error-free and error-prone lesion bypass by human DNA polymerase kappa in vitro.

Zhang Y, Yuan F, Wu X, Wang M, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z.

Nucleic Acids Res. 2000 Nov 1;28(21):4138-46.

PMID:
11058110
[PubMed - indexed for MEDLINE]
Free PMC Article

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