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Items: 1 to 20 of 101

1.

Nodal and lefty signaling regulates the growth of pancreatic cells.

Zhang YQ, Sterling L, Stotland A, Hua H, Kritzik M, Sarvetnick N.

Dev Dyn. 2008 May;237(5):1255-67. doi: 10.1002/dvdy.21527.

2.

Two modes by which Lefty proteins inhibit nodal signaling.

Chen C, Shen MM.

Curr Biol. 2004 Apr 6;14(7):618-24.

3.
4.

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal.

Meno C, Shimono A, Saijoh Y, Yashiro K, Mochida K, Ohishi S, Noji S, Kondoh H, Hamada H.

Cell. 1998 Aug 7;94(3):287-97.

5.

Lefty proteins are long-range inhibitors of squint-mediated nodal signaling.

Chen Y, Schier AF.

Curr Biol. 2002 Dec 23;12(24):2124-8.

7.

Increased expression of Nodal correlates with reduced patient survival in pancreatic cancer.

Kong B, Wang W, Esposito I, Friess H, Michalski CW, Kleeff J.

Pancreatology. 2015 Mar-Apr;15(2):156-61. doi: 10.1016/j.pan.2015.02.001. Epub 2015 Feb 12.

PMID:
25708930
8.

TGFβ signaling in establishing left-right asymmetry.

Shiratori H, Hamada H.

Semin Cell Dev Biol. 2014 Aug;32:80-4. doi: 10.1016/j.semcdb.2014.03.029. Epub 2014 Apr 2. Review.

PMID:
24704359
9.

Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells.

Zhao F, Huang F, Tang M, Li X, Zhang N, Amfilochiadis A, Li Y, Hu R, Jin T, Peng C, Wang Q.

Am J Physiol Endocrinol Metab. 2012 Jul 1;303(1):E132-43. doi: 10.1152/ajpendo.00074.2012. Epub 2012 May 1.

10.

Inhibition of Activin/Nodal signaling promotes specification of human embryonic stem cells into neuroectoderm.

Smith JR, Vallier L, Lupo G, Alexander M, Harris WA, Pedersen RA.

Dev Biol. 2008 Jan 1;313(1):107-17. Epub 2007 Oct 11.

11.

Smad5 is essential for left-right asymmetry in mice.

Chang H, Zwijsen A, Vogel H, Huylebroeck D, Matzuk MM.

Dev Biol. 2000 Mar 1;219(1):71-8.

12.

Transforming growth factor β and Ras/MEK/ERK signaling regulate the expression level of a novel tumor suppressor Lefty.

Miyata N, Azuma T, Hozawa S, Higuchi H, Yokoyama A, Kabashima A, Igarashi T, Saeki K, Hibi T.

Pancreas. 2012 Jul;41(5):745-52. doi: 10.1097/MPA.0b013e31823b66d3.

PMID:
22441145
13.

Growth factor-induced signaling of the pancreatic epithelium.

Kayali AG, Stotland A, Gunst KV, Kritzik M, Liu G, Dabernat S, Zhang YQ, Wu W, Sarvetnick N.

J Endocrinol. 2005 Apr;185(1):45-56.

14.

Cripto is a noncompetitive activin antagonist that forms analogous signaling complexes with activin and nodal.

Kelber JA, Shani G, Booker EC, Vale WW, Gray PC.

J Biol Chem. 2008 Feb 22;283(8):4490-500. Epub 2007 Dec 18.

15.

Lefty proteins exhibit unique processing and activate the MAPK pathway.

Ulloa L, Creemers JW, Roy S, Liu S, Mason J, Tabibzadeh S.

J Biol Chem. 2001 Jun 15;276(24):21387-96. Epub 2001 Feb 20.

16.

Role of asymmetric signals in left-right patterning in the mouse.

Hamada H, Meno C, Saijoh Y, Adachi H, Yashiro K, Sakuma R, Shiratori H.

Am J Med Genet. 2001 Jul 15;101(4):324-7.

PMID:
11471154
17.

A Nodal- and ALK4-independent signaling pathway activated by Cripto-1 through Glypican-1 and c-Src.

Bianco C, Strizzi L, Rehman A, Normanno N, Wechselberger C, Sun Y, Khan N, Hirota M, Adkins H, Williams K, Margolis RU, Sanicola M, Salomon DS.

Cancer Res. 2003 Mar 15;63(6):1192-7. Erratum in: Cancer Res. 2003 Apr 15;63(8):1997.

18.
19.

Lefty acts as an essential modulator of Nodal activity during sea urchin oral-aboral axis formation.

Duboc V, Lapraz F, Besnardeau L, Lepage T.

Dev Biol. 2008 Aug 1;320(1):49-59. doi: 10.1016/j.ydbio.2008.04.012. Epub 2008 Apr 20.

20.

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion.

Sakuma R, Ohnishi Yi Y, Meno C, Fujii H, Juan H, Takeuchi J, Ogura T, Li E, Miyazono K, Hamada H.

Genes Cells. 2002 Apr;7(4):401-12.

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