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Items: 1 to 20 of 141

1.

Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules.

Russel FG, Koenderink JB, Masereeuw R.

Trends Pharmacol Sci. 2008 Apr;29(4):200-7. doi: 10.1016/j.tips.2008.01.006. Epub 2008 Mar 18. Review.

PMID:
18353444
2.

Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5).

Ritter CA, Jedlitschky G, Meyer zu Schwabedissen H, Grube M, Köck K, Kroemer HK.

Drug Metab Rev. 2005;37(1):253-78. Review.

PMID:
15747503
3.

Substrates and inhibitors of human multidrug resistance associated proteins and the implications in drug development.

Zhou SF, Wang LL, Di YM, Xue CC, Duan W, Li CG, Li Y.

Curr Med Chem. 2008;15(20):1981-2039. Review.

PMID:
18691054
4.

Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

Bai J, Lai L, Yeo HC, Goh BC, Tan TM.

Int J Biochem Cell Biol. 2004 Feb;36(2):247-57.

PMID:
14643890
5.
6.

Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites.

Van Aubel RA, Smeets PH, van den Heuvel JJ, Russel FG.

Am J Physiol Renal Physiol. 2005 Feb;288(2):F327-33. Epub 2004 Sep 28.

8.

Functional role of arginine 375 in transmembrane helix 6 of multidrug resistance protein 4 (MRP4/ABCC4).

El-Sheikh AA, van den Heuvel JJ, Krieger E, Russel FG, Koenderink JB.

Mol Pharmacol. 2008 Oct;74(4):964-71. doi: 10.1124/mol.107.043661. Epub 2008 Jul 8.

9.

Interaction of nonsteroidal anti-inflammatory drugs with multidrug resistance protein (MRP) 2/ABCC2- and MRP4/ABCC4-mediated methotrexate transport.

El-Sheikh AA, van den Heuvel JJ, Koenderink JB, Russel FG.

J Pharmacol Exp Ther. 2007 Jan;320(1):229-35. Epub 2006 Sep 27.

10.

The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.

Jedlitschky G, Tirschmann K, Lubenow LE, Nieuwenhuis HK, Akkerman JW, Greinacher A, Kroemer HK.

Blood. 2004 Dec 1;104(12):3603-10. Epub 2004 Aug 5.

11.

Molecular model of the outward facing state of the human multidrug resistance protein 4 (MRP4/ABCC4).

Ravna AW, Sager G.

Bioorg Med Chem Lett. 2008 Jun 15;18(12):3481-3. doi: 10.1016/j.bmcl.2008.05.047. Epub 2008 May 16.

PMID:
18513968
13.

Phenylalanine 368 of multidrug resistance-associated protein 4 (MRP4/ABCC4) plays a crucial role in substrate-specific transport activity.

Wittgen HG, van den Heuvel JJ, Krieger E, Schaftenaar G, Russel FG, Koenderink JB.

Biochem Pharmacol. 2012 Aug 1;84(3):366-73. doi: 10.1016/j.bcp.2012.04.012. Epub 2012 Apr 21.

PMID:
22542979
14.

Involvement of NHERF1 in apical membrane localization of MRP4 in polarized kidney cells.

Hoque MT, Conseil G, Cole SP.

Biochem Biophys Res Commun. 2009 Jan 30;379(1):60-4. doi: 10.1016/j.bbrc.2008.12.014. Epub 2008 Dec 13.

PMID:
19073137
15.

Down-regulation of Na+/H+ exchanger regulatory factor 1 increases expression and function of multidrug resistance protein 4.

Hoque MT, Cole SP.

Cancer Res. 2008 Jun 15;68(12):4802-9. doi: 10.1158/0008-5472.CAN-07-6778.

16.

Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.

Chen ZS, Lee K, Walther S, Raftogianis RB, Kuwano M, Zeng H, Kruh GD.

Cancer Res. 2002 Jun 1;62(11):3144-50.

17.

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4.

El-Sheikh AA, van den Heuvel JJ, Koenderink JB, Russel FG.

Br J Pharmacol. 2008 Dec;155(7):1066-75. doi: 10.1038/bjp.2008.343. Epub 2008 Aug 25.

18.

Role of MRP4 and MRP5 in biology and chemotherapy.

Sampath J, Adachi M, Hatse S, Naesens L, Balzarini J, Flatley RM, Matherly LH, Schuetz JD.

AAPS PharmSci. 2002;4(3):E14. Review.

19.

Androgen regulation of multidrug resistance-associated protein 4 (MRP4/ABCC4) in prostate cancer.

Ho LL, Kench JG, Handelsman DJ, Scheffer GL, Stricker PD, Grygiel JG, Sutherland RL, Henshall SM, Allen JD, Horvath LG.

Prostate. 2008 Sep 15;68(13):1421-9. doi: 10.1002/pros.20809.

PMID:
18615486
20.

Multidrug resistance-associated proteins 3, 4, and 5.

Borst P, de Wolf C, van de Wetering K.

Pflugers Arch. 2007 Feb;453(5):661-73. Epub 2006 Apr 4. Review.

PMID:
16586096
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