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Results: 1 to 20 of 139

Similar articles for PubMed (Select 18337106)

1.

Synthesis of caged 2,3,3a,7a-tetrahydro-3,6-methanobenzofuran-7(6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid.

Kuemmerle J, Jiang S, Tseng B, Kasibhatla S, Drewe J, Cai SX.

Bioorg Med Chem. 2008 Apr 15;16(8):4233-41. doi: 10.1016/j.bmc.2008.02.084. Epub 2008 Feb 29.

PMID:
18337106
2.

Synthesis and evaluation of caged Garcinia xanthones.

Batova A, Lam T, Wascholowski V, Yu AL, Giannis A, Theodorakis EA.

Org Biomol Chem. 2007 Feb 7;5(3):494-500. Epub 2006 Dec 20.

PMID:
17252132
3.

Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay.

Zhang HZ, Kasibhatla S, Wang Y, Herich J, Guastella J, Tseng B, Drewe J, Cai SX.

Bioorg Med Chem. 2004 Jan 15;12(2):309-17.

PMID:
14723951
4.

Studies on chemical structure modification and biology of a natural product, gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid.

Wang J, Zhao L, Hu Y, Guo Q, Zhang L, Wang X, Li N, You Q.

Eur J Med Chem. 2009 Jun;44(6):2611-20. doi: 10.1016/j.ejmech.2008.09.034. Epub 2008 Oct 7.

PMID:
18996626
5.

Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents.

Wang J, Ma J, You Q, Zhao L, Wang F, Li C, Guo Q.

Eur J Med Chem. 2010 Sep;45(9):4343-53. doi: 10.1016/j.ejmech.2010.04.037. Epub 2010 May 13.

PMID:
20605273
6.

Studies on chemical modification and biology of a natural product, gambogic acid (III): determination of the essential pharmacophore for biological activity.

Wang X, Lu N, Yang Q, Gong D, Lin C, Zhang S, Xi M, Gao Y, Wei L, Guo Q, You Q.

Eur J Med Chem. 2011 Apr;46(4):1280-90. doi: 10.1016/j.ejmech.2011.01.051. Epub 2011 Feb 3.

PMID:
21334116
7.

Evaluation of the pharmacophoric motif of the caged Garcinia xanthones.

Chantarasriwong O, Cho WC, Batova A, Chavasiri W, Moore C, Rheingold AL, Theodorakis EA.

Org Biomol Chem. 2009 Dec 7;7(23):4886-94. doi: 10.1039/b913496d. Epub 2009 Sep 24.

8.

Caged Garcinia xanthones: development since 1937.

Han QB, Xu HX.

Curr Med Chem. 2009;16(28):3775-96. Review.

PMID:
19747141
9.

A-ring oxygenation modulates the chemistry and bioactivity of caged Garcinia xanthones.

Elbel KM, Guizzunti G, Theodoraki MA, Xu J, Batova A, Dakanali M, Theodorakis EA.

Org Biomol Chem. 2013 May 28;11(20):3341-8. doi: 10.1039/c3ob40395e.

10.

Synthesis and evaluation of novel aza-caged Garcinia xanthones.

Zhang X, Li X, Sun H, Jiang Z, Tao L, Gao Y, Guo Q, You Q.

Org Biomol Chem. 2012 Apr 28;10(16):3288-99. doi: 10.1039/c2ob07088j. Epub 2012 Mar 12.

PMID:
22407464
11.

Synthesis and evaluation of gambogic acid derivatives as antitumor agents. Part III.

Guo XK, Sun HP, Shen S, Sun Y, Xie FL, Tao L, Guo QL, Jiang C, You QD.

Chem Biodivers. 2013 Jan;10(1):73-85. doi: 10.1002/cbdv.201200126.

PMID:
23341209
12.

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

Sun H, Chen F, Wang X, Liu Z, Yang Q, Zhang X, Zhu J, Qiang L, Guo Q, You Q.

Eur J Med Chem. 2012 May;51:110-23. doi: 10.1016/j.ejmech.2012.02.029. Epub 2012 Mar 3.

PMID:
22472167
13.

Unified synthesis of caged Garcinia natural products based on a site-selective Claisen/Diels-Alder/Claisen rearrangement.

Tisdale EJ, Slobodov I, Theodorakis EA.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12030-5. Epub 2004 Jun 21.

14.

Studies on chemical-structure modification and structure-activity relationship of gambogic acid derivatives at carbon(34).

Zhang XJ, Li X, Yang YR, Sun HP, Gao Y, Zhang L, Wang JX, Guo QL, You QD.

Chem Biodivers. 2012 Oct;9(10):2295-308. doi: 10.1002/cbdv.201200081.

PMID:
23081928
15.

Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells.

Nie F, Zhang X, Qi Q, Yang L, Yang Y, Liu W, Lu N, Wu Z, You Q, Guo Q.

Toxicology. 2009 Jun 16;260(1-3):60-7. doi: 10.1016/j.tox.2009.03.010. Epub 2009 Mar 24.

PMID:
19464570
17.

Studies on chemical structure modification and structure-activity relationship of derivatives of gambogic acid at C(39).

Sun HP, Liu ZL, Xue X, Gao Y, Zhang L, Wang JX, Guo QL, You QD.

Chem Biodivers. 2012 Aug;9(8):1579-90. doi: 10.1002/cbdv.201100415.

PMID:
22899618
18.

Prenylated caged xanthones: chemistry and biology.

Anantachoke N, Tuchinda P, Kuhakarn C, Pohmakotr M, Reutrakul V.

Pharm Biol. 2012 Jan;50(1):78-91. doi: 10.3109/13880209.2011.636176. Review.

PMID:
22196584
19.
20.

Recent cancer drug development with xanthone structures.

Na Y.

J Pharm Pharmacol. 2009 Jun;61(6):707-12. doi: 10.1211/jpp/61.06.0002. Review.

PMID:
19505360
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