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Items: 1 to 20 of 100

1.

Tempol protects against oxidative damage and delays epithelial tumor onset in Fanconi anemia mice.

Zhang QS, Eaton L, Snyder ER, Houghtaling S, Mitchell JB, Finegold M, Van Waes C, Grompe M.

Cancer Res. 2008 Mar 1;68(5):1601-8. doi: 10.1158/0008-5472.CAN-07-5186.

2.

Heterozygosity for p53 (Trp53+/-) accelerates epithelial tumor formation in fanconi anemia complementation group D2 (Fancd2) knockout mice.

Houghtaling S, Granville L, Akkari Y, Torimaru Y, Olson S, Finegold M, Grompe M.

Cancer Res. 2005 Jan 1;65(1):85-91.

3.

Evaluation of resveratrol and N-acetylcysteine for cancer chemoprevention in a Fanconi anemia murine model.

Zhang QS, Marquez-Loza L, Sheehan AM, Watanabe-Smith K, Eaton L, Benedetti E, Major A, Schubert K, Deater M, Joseph E, Grompe M.

Pediatr Blood Cancer. 2014 Apr;61(4):740-2. doi: 10.1002/pbc.24780. Epub 2013 Sep 20.

4.

Radiologic differences between bone marrow stromal and hematopoietic progenitor cell lines from Fanconi Anemia (Fancd2(-/-)) mice.

Berhane H, Epperly MW, Goff J, Kalash R, Cao S, Franicola D, Zhang X, Shields D, Houghton F, Wang H, Wipf P, Parmar K, Greenberger JS.

Radiat Res. 2014 Jan;181(1):76-89. doi: 10.1667/RR13405.1. Epub 2014 Jan 7.

5.

Effect of the anti-oxidant tempol on fetal growth in a mouse model of fetal growth restriction.

Stanley JL, Andersson IJ, Hirt CJ, Moore L, Dilworth MR, Chade AR, Sibley CP, Davidge ST, Baker PN.

Biol Reprod. 2012 Jul 26;87(1):25, 1-8. doi: 10.1095/biolreprod.111.096198. Print 2012 Jul.

6.
7.

Cancer chemoprevention by the antioxidant tempol acts partially via the p53 tumor suppressor.

Erker L, Schubert R, Yakushiji H, Barlow C, Larson D, Mitchell JB, Wynshaw-Boris A.

Hum Mol Genet. 2005 Jun 15;14(12):1699-708. Epub 2005 May 11.

8.

Effects of tempol and redox-cycling nitroxides in models of oxidative stress.

Wilcox CS.

Pharmacol Ther. 2010 May;126(2):119-45. doi: 10.1016/j.pharmthera.2010.01.003. Epub 2010 Feb 11. Review.

9.

Epithelial cancer in Fanconi anemia complementation group D2 (Fancd2) knockout mice.

Houghtaling S, Timmers C, Noll M, Finegold MJ, Jones SN, Meyn MS, Grompe M.

Genes Dev. 2003 Aug 15;17(16):2021-35. Epub 2003 Jul 31.

10.

Bone marrow failure in the Fanconi anemia group C mouse model after DNA damage.

Carreau M, Gan OI, Liu L, Doedens M, McKerlie C, Dick JE, Buchwald M.

Blood. 1998 Apr 15;91(8):2737-44.

11.

Chronic tempol prevents hypertension, proteinuria, and poor feto-placental outcomes in BPH/5 mouse model of preeclampsia.

Hoffmann DS, Weydert CJ, Lazartigues E, Kutschke WJ, Kienzle MF, Leach JE, Sharma JA, Sharma RV, Davisson RL.

Hypertension. 2008 Apr;51(4):1058-65. doi: 10.1161/HYPERTENSIONAHA.107.107219. Epub 2008 Feb 7.

12.

Oxidative stress in Fanconi anaemia: from cells and molecules towards prospects in clinical management.

Pagano G, Talamanca AA, Castello G, Pallardó FV, Zatterale A, Degan P.

Biol Chem. 2012 Jan;393(1-2):11-21. doi: 10.1515/BC-2011-227. Review.

PMID:
22628295
13.

GS-nitroxide (JP4-039)-mediated radioprotection of human Fanconi anemia cell lines.

Bernard ME, Kim H, Berhane H, Epperly MW, Franicola D, Zhang X, Houghton F, Shields D, Wang H, Bakkenist CJ, Frantz MC, Forbeck EM, Goff JP, Wipf P, Greenberger JS.

Radiat Res. 2011 Nov;176(5):603-12. Epub 2011 Sep 22.

14.

Effect of tempol on redox homeostasis and stress tolerance in mimetically aged Drosophila.

Aksu U, Yanar K, Terzioglu D, Erkol T, Ece E, Aydin S, Uslu E, Çakatay U.

Arch Insect Biochem Physiol. 2014 Sep;87(1):13-25. doi: 10.1002/arch.21176. Epub 2014 Jul 18.

PMID:
25044374
15.

Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.

Park JW, Pitot HC, Strati K, Spardy N, Duensing S, Grompe M, Lambert PF.

Cancer Res. 2010 Dec 1;70(23):9959-68. doi: 10.1158/0008-5472.CAN-10-1291. Epub 2010 Oct 8.

16.

Tempol, one of nitroxides, is a novel ultraviolet-A1 radiation protector for human dermal fibroblasts.

Yan SX, Hong XY, Hu Y, Liao KH.

J Dermatol Sci. 2005 Mar;37(3):137-43. Epub 2005 Jan 21.

PMID:
15734282
17.

siRNA screening identifies differences in the Fanconi anemia pathway in BALB/c-Trp53+/- with susceptibility versus C57BL/6-Trp53+/- mice with resistance to mammary tumors.

Böhringer M, Obermeier K, Griner N, Waldraff D, Dickinson E, Eirich K, Schindler D, Hagen M, Jerry DJ, Wiesmüller L.

Oncogene. 2013 Nov 28;32(48):5458-70. doi: 10.1038/onc.2013.38. Epub 2013 Feb 25.

18.

The nitroxide Tempol affords protection against ultraviolet radiation in a transgenic murine fibroblast culture model of cutaneous photoaging.

Bernstein EF, Kong SK, Brown DB, Kwak BC, Takeuchi T, Gasparro FP, Uitto J.

Exp Dermatol. 2001 Feb;10(1):55-61.

PMID:
11168580
19.

Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage.

Hahn SM, Mitchell JB, Shacter E.

Free Radic Biol Med. 1997;23(6):879-84.

PMID:
9378367
20.

Hematopoietic stem cell defects in mice with deficiency of Fancd2 or Usp1.

Parmar K, Kim J, Sykes SM, Shimamura A, Stuckert P, Zhu K, Hamilton A, Deloach MK, Kutok JL, Akashi K, Gilliland DG, D'andrea A.

Stem Cells. 2010 Jul;28(7):1186-95. doi: 10.1002/stem.437.

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