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Items: 1 to 20 of 138


The zinc-binding motif of human RECQ5beta suppresses the intrinsic strand-annealing activity of its DExH helicase domain and is essential for the helicase activity of the enzyme.

Ren H, Dou SX, Zhang XD, Wang PY, Kanagaraj R, Liu JL, Janscak P, Hu JS, Xi XG.

Biochem J. 2008 Jun 15;412(3):425-33. doi: 10.1042/BJ20071150.


The zinc finger motif of Escherichia coli RecQ is implicated in both DNA binding and protein folding.

Liu JL, Rigolet P, Dou SX, Wang PY, Xi XG.

J Biol Chem. 2004 Oct 8;279(41):42794-802. Epub 2004 Jul 29.


Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide.

Garcia PL, Liu Y, Jiricny J, West SC, Janscak P.

EMBO J. 2004 Jul 21;23(14):2882-91. Epub 2004 Jul 8.


Enzymatic mechanism of the WRN helicase/nuclease.

Brosh RM Jr, Opresko PL, Bohr VA.

Methods Enzymol. 2006;409:52-85.


Biochemical characterization of the DNA helicase activity of the escherichia coli RecQ helicase.

Harmon FG, Kowalczykowski SC.

J Biol Chem. 2001 Jan 5;276(1):232-43.


Structure of the human RECQ1 helicase reveals a putative strand-separation pin.

Pike AC, Shrestha B, Popuri V, Burgess-Brown N, Muzzolini L, Costantini S, Vindigni A, Gileadi O.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1039-44. doi: 10.1073/pnas.0806908106. Epub 2009 Jan 16.


The Bloom's syndrome helicase promotes the annealing of complementary single-stranded DNA.

Cheok CF, Wu L, Garcia PL, Janscak P, Hickson ID.

Nucleic Acids Res. 2005 Jul 15;33(12):3932-41. Print 2005.


Conferring substrate specificity to DNA helicases: role of the RecQ HRDC domain.

Bernstein DA, Keck JL.

Structure. 2005 Aug;13(8):1173-82.


Association of human DNA helicase RecQ5beta with RNA polymerase II and its possible role in transcription.

Izumikawa K, Yanagida M, Hayano T, Tachikawa H, Komatsu W, Shimamoto A, Futami K, Furuichi Y, Shinkawa T, Yamauchi Y, Isobe T, Takahashi N.

Biochem J. 2008 Aug 1;413(3):505-16. doi: 10.1042/BJ20071392.


Biochemical analysis of the DNA unwinding and strand annealing activities catalyzed by human RECQ1.

Sharma S, Sommers JA, Choudhary S, Faulkner JK, Cui S, Andreoli L, Muzzolini L, Vindigni A, Brosh RM Jr.

J Biol Chem. 2005 Jul 29;280(30):28072-84. Epub 2005 May 16.


The arginine finger of the Bloom syndrome protein: its structural organization and its role in energy coupling.

Ren H, Dou SX, Rigolet P, Yang Y, Wang PY, Amor-Gueret M, Xi XG.

Nucleic Acids Res. 2007;35(18):6029-41. Epub 2007 Aug 30.


Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN.

Kitano K, Kim SY, Hakoshima T.

Structure. 2010 Feb 10;18(2):177-87. doi: 10.1016/j.str.2009.12.011.


Structural and functional characterizations reveal the importance of a zinc binding domain in Bloom's syndrome helicase.

Guo RB, Rigolet P, Zargarian L, Fermandjian S, Xi XG.

Nucleic Acids Res. 2005 Jun 1;33(10):3109-24. Print 2005.


Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork.

Kanagaraj R, Saydam N, Garcia PL, Zheng L, Janscak P.

Nucleic Acids Res. 2006;34(18):5217-31. Epub 2006 Sep 26.


The DNA binding properties of the Escherichia coli RecQ helicase.

Dou SX, Wang PY, Xu HQ, Xi XG.

J Biol Chem. 2004 Feb 20;279(8):6354-63. Epub 2003 Dec 9.

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