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Results: 1 to 20 of 213

1.

Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(-/-) mice.

Collett A, Higgs NB, Gironella M, Zeef LA, Hayes A, Salmo E, Haboubi N, Iovanna JL, Carlson GL, Warhurst G.

Inflamm Bowel Dis. 2008 May;14(5):620-31. doi: 10.1002/ibd.20375.

PMID:
18275070
[PubMed - indexed for MEDLINE]
2.

A novel model of inflammatory bowel disease: mice deficient for the multiple drug resistance gene, mdr1a, spontaneously develop colitis.

Panwala CM, Jones JC, Viney JL.

J Immunol. 1998 Nov 15;161(10):5733-44.

PMID:
9820555
[PubMed - indexed for MEDLINE]
Free Article
3.

Enteric glia regulate intestinal barrier function and inflammation via release of S-nitrosoglutathione.

Savidge TC, Newman P, Pothoulakis C, Ruhl A, Neunlist M, Bourreille A, Hurst R, Sofroniew MV.

Gastroenterology. 2007 Apr;132(4):1344-58. Epub 2007 Feb 1.

PMID:
17408650
[PubMed - indexed for MEDLINE]
4.

Epithelial dysfunction associated with the development of colitis in conventionally housed mdr1a-/- mice.

Resta-Lenert S, Smitham J, Barrett KE.

Am J Physiol Gastrointest Liver Physiol. 2005 Jul;289(1):G153-62. Epub 2005 Mar 17. Erratum in: Am J Physiol Gastrointest Liver Physiol. 2005 Dec;289(6):G1176.

PMID:
15774938
[PubMed - indexed for MEDLINE]
Free Article
5.

The effects of dietary curcumin and rutin on colonic inflammation and gene expression in multidrug resistance gene-deficient (mdr1a-/-) mice, a model of inflammatory bowel diseases.

Nones K, Dommels YE, Martell S, Butts C, McNabb WC, Park ZA, Zhu S, Hedderley D, Barnett MP, Roy NC.

Br J Nutr. 2009 Jan;101(2):169-81. doi: 10.1017/S0007114508009847. Epub 2008 Sep 2.

PMID:
18761777
[PubMed - indexed for MEDLINE]
6.

Circadian clock-controlled intestinal expression of the multidrug-resistance gene mdr1a in mice.

Murakami Y, Higashi Y, Matsunaga N, Koyanagi S, Ohdo S.

Gastroenterology. 2008 Nov;135(5):1636-1644.e3. doi: 10.1053/j.gastro.2008.07.073. Epub 2008 Aug 3.

PMID:
18773899
[PubMed - indexed for MEDLINE]
7.

A defect in epithelial barrier integrity is not required for a systemic response to bacterial antigens or intestinal injury in T cell receptor-alpha gene-deficient mice.

Sydora BC, Tavernini MM, Doyle J, Fedorak RN.

Inflamm Bowel Dis. 2006 Aug;12(8):750-7.

PMID:
16917231
[PubMed - indexed for MEDLINE]
8.

Phenotypic changes in colonocytes following acute stress or activation of mast cells in mice: implications for delayed epithelial barrier dysfunction.

Demaude J, Salvador-Cartier C, Fioramonti J, Ferrier L, Bueno L.

Gut. 2006 May;55(5):655-61. Epub 2005 Nov 18.

PMID:
16299034
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Epithelial vanin-1 controls inflammation-driven carcinogenesis in the colitis-associated colon cancer model.

Pouyet L, Roisin-Bouffay C, Clément A, Millet V, Garcia S, Chasson L, Issaly N, Rostan A, Hofman P, Naquet P, Galland F.

Inflamm Bowel Dis. 2010 Jan;16(1):96-104. doi: 10.1002/ibd.21031.

PMID:
19572375
[PubMed - indexed for MEDLINE]
10.

Critical role for P-glycoprotein expression in hematopoietic cells in the FVB.Mdr1a(-/-) model of colitis.

Staley EM, Dimmitt RA, Schoeb TR, Tanner SM, Lorenz RG.

J Pediatr Gastroenterol Nutr. 2011 Dec;53(6):666-73. doi: 10.1097/MPG.0b013e31822860f1.

PMID:
21681110
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment.

Habtezion A, Toivola DM, Butcher EC, Omary MB.

J Cell Sci. 2005 May 1;118(Pt 9):1971-80. Epub 2005 Apr 19.

PMID:
15840656
[PubMed - indexed for MEDLINE]
Free Article
12.

Expression profiles of cytokines and chemokines in murine MDR1a-/- colitis.

Masunaga Y, Noto T, Suzuki K, Takahashi K, Shimizu Y, Morokata T.

Inflamm Res. 2007 Nov;56(11):439-46. doi: 10.1007/s00011-007-6078-6.

PMID:
18224285
[PubMed - indexed for MEDLINE]
13.

Probiotic administration alters the gut flora and attenuates colitis in mice administered dextran sodium sulfate.

Nanda Kumar NS, Balamurugan R, Jayakanthan K, Pulimood A, Pugazhendhi S, Ramakrishna BS.

J Gastroenterol Hepatol. 2008 Dec;23(12):1834-9. doi: 10.1111/j.1440-1746.2008.05723.x.

PMID:
19120873
[PubMed - indexed for MEDLINE]
14.

Colonic gene expression patterns of mucin Muc2 knockout mice reveal various phases in colitis development.

Lu P, Burger-van Paassen N, van der Sluis M, Witte-Bouma J, Kerckaert JP, van Goudoever JB, Van Seuningen I, Renes IB.

Inflamm Bowel Dis. 2011 Oct;17(10):2047-57. doi: 10.1002/ibd.21592. Epub 2011 Jan 6.

PMID:
21910166
[PubMed - indexed for MEDLINE]
15.

Changes in colon gene expression associated with increased colon inflammation in interleukin-10 gene-deficient mice inoculated with Enterococcus species.

Barnett MP, McNabb WC, Cookson AL, Zhu S, Davy M, Knoch B, Nones K, Hodgkinson AJ, Roy NC.

BMC Immunol. 2010 Jul 15;11:39. doi: 10.1186/1471-2172-11-39.

PMID:
20630110
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Region-dependent modulation of intestinal permeability by drug efflux transporters: in vitro studies in mdr1a(-/-) mouse intestine.

Stephens RH, Tanianis-Hughes J, Higgs NB, Humphrey M, Warhurst G.

J Pharmacol Exp Ther. 2002 Dec;303(3):1095-101.

PMID:
12438532
[PubMed - indexed for MEDLINE]
Free Article
17.

Increased expression of HIP/PAP and regenerating gene III in human inflammatory bowel disease and a murine bacterial reconstitution model.

Ogawa H, Fukushima K, Naito H, Funayama Y, Unno M, Takahashi K, Kitayama T, Matsuno S, Ohtani H, Takasawa S, Okamoto H, Sasaki I.

Inflamm Bowel Dis. 2003 May;9(3):162-70.

PMID:
12792221
[PubMed - indexed for MEDLINE]
18.

Loss of TLR2 worsens spontaneous colitis in MDR1A deficiency through commensally induced pyroptosis.

Ey B, Eyking A, Klepak M, Salzman NH, Göthert JR, Rünzi M, Schmid KW, Gerken G, Podolsky DK, Cario E.

J Immunol. 2013 Jun 1;190(11):5676-88. doi: 10.4049/jimmunol.1201592. Epub 2013 May 1.

PMID:
23636052
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Resolution of P-glycoprotein and non-P-glycoprotein effects on drug permeability using intestinal tissues from mdr1a (-/-) mice.

Stephens RH, O'Neill CA, Bennett J, Humphrey M, Henry B, Rowland M, Warhurst G.

Br J Pharmacol. 2002 Apr;135(8):2038-46.

PMID:
11959808
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Elevated expression of hepatic proliferative markers during early hepatocarcinogenesis in hepatitis-B virus transgenic mice lacking mdr1a-encoded P-glycoprotein.

Bao JJ, Lee BP, Stephens LC, Sahin AA, Van NT, Johnston DA, Ou CN, Kuo MT.

Mol Carcinog. 2000 Oct;29(2):103-11.

PMID:
11074607
[PubMed - indexed for MEDLINE]
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