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Results: 1 to 20 of 507

1.

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.

Ronesi JA, Huber KM.

Sci Signal. 2008 Feb 5;1(5):pe6. doi: 10.1126/stke.15pe6. Review.

PMID:
18272470
[PubMed - indexed for MEDLINE]
2.

The state of synapses in fragile X syndrome.

Pfeiffer BE, Huber KM.

Neuroscientist. 2009 Oct;15(5):549-67. doi: 10.1177/1073858409333075. Epub 2009 Mar 26. Review.

PMID:
19325170
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Metabotropic glutamate receptor activation regulates fragile x mental retardation protein and FMR1 mRNA localization differentially in dendrites and at synapses.

Antar LN, Afroz R, Dictenberg JB, Carroll RC, Bassell GJ.

J Neurosci. 2004 Mar 17;24(11):2648-55.

PMID:
15028757
[PubMed - indexed for MEDLINE]
Free Article
4.

Fragile X mental retardation protein induces synapse loss through acute postsynaptic translational regulation.

Pfeiffer BE, Huber KM.

J Neurosci. 2007 Mar 21;27(12):3120-30.

PMID:
17376973
[PubMed - indexed for MEDLINE]
Free Article
5.

Fragile X mental retardation protein deficiency leads to excessive mGluR5-dependent internalization of AMPA receptors.

Nakamoto M, Nalavadi V, Epstein MP, Narayanan U, Bassell GJ, Warren ST.

Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15537-42. Epub 2007 Sep 19.

PMID:
17881561
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.

Nosyreva ED, Huber KM.

J Neurophysiol. 2006 May;95(5):3291-5. Epub 2006 Feb 1.

PMID:
16452252
[PubMed - indexed for MEDLINE]
Free Article
7.

The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain.

Aschrafi A, Cunningham BA, Edelman GM, Vanderklish PW.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2180-5. Epub 2005 Jan 31.

PMID:
15684045
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome.

Muddashetty RS, Kelić S, Gross C, Xu M, Bassell GJ.

J Neurosci. 2007 May 16;27(20):5338-48.

PMID:
17507556
[PubMed - indexed for MEDLINE]
Free Article
9.

Altered synaptic plasticity in a mouse model of fragile X mental retardation.

Huber KM, Gallagher SM, Warren ST, Bear MF.

Proc Natl Acad Sci U S A. 2002 May 28;99(11):7746-50.

PMID:
12032354
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice.

Iliff AJ, Renoux AJ, Krans A, Usdin K, Sutton MA, Todd PK.

Hum Mol Genet. 2013 Mar 15;22(6):1180-92. doi: 10.1093/hmg/dds525. Epub 2012 Dec 18.

PMID:
23250915
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

S6K1 phosphorylates and regulates fragile X mental retardation protein (FMRP) with the neuronal protein synthesis-dependent mammalian target of rapamycin (mTOR) signaling cascade.

Narayanan U, Nalavadi V, Nakamoto M, Thomas G, Ceman S, Bassell GJ, Warren ST.

J Biol Chem. 2008 Jul 4;283(27):18478-82. doi: 10.1074/jbc.C800055200. Epub 2008 May 12.

PMID:
18474609
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Local functions for FMRP in axon growth cone motility and activity-dependent regulation of filopodia and spine synapses.

Antar LN, Li C, Zhang H, Carroll RC, Bassell GJ.

Mol Cell Neurosci. 2006 May-Jun;32(1-2):37-48. Epub 2006 May 2.

PMID:
16631377
[PubMed - indexed for MEDLINE]
13.

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.

Bassell GJ, Warren ST.

Neuron. 2008 Oct 23;60(2):201-14. doi: 10.1016/j.neuron.2008.10.004. Review.

PMID:
18957214
[PubMed - indexed for MEDLINE]
Free PMC Article
14.
15.

A reduced number of metabotropic glutamate subtype 5 receptors are associated with constitutive homer proteins in a mouse model of fragile X syndrome.

Giuffrida R, Musumeci S, D'Antoni S, Bonaccorso CM, Giuffrida-Stella AM, Oostra BA, Catania MV.

J Neurosci. 2005 Sep 28;25(39):8908-16.

PMID:
16192381
[PubMed - indexed for MEDLINE]
Free Article
16.

Differential translation and fragile X syndrome.

Vanderklish PW, Edelman GM.

Genes Brain Behav. 2005 Aug;4(6):360-84. Review.

PMID:
16098135
[PubMed - indexed for MEDLINE]
17.

A decade of molecular studies of fragile X syndrome.

O'Donnell WT, Warren ST.

Annu Rev Neurosci. 2002;25:315-38. Epub 2002 Mar 20. Review.

PMID:
12052912
[PubMed - indexed for MEDLINE]
18.

The fragile X-cerebellum connection.

Huber KM.

Trends Neurosci. 2006 Apr;29(4):183-5. Epub 2006 Feb 28. Review.

PMID:
16500716
[PubMed - indexed for MEDLINE]
19.

Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.

Gross C, Nakamoto M, Yao X, Chan CB, Yim SY, Ye K, Warren ST, Bassell GJ.

J Neurosci. 2010 Aug 11;30(32):10624-38. doi: 10.1523/JNEUROSCI.0402-10.2010.

PMID:
20702695
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Astroglial FMRP-dependent translational down-regulation of mGluR5 underlies glutamate transporter GLT1 dysregulation in the fragile X mouse.

Higashimori H, Morel L, Huth J, Lindemann L, Dulla C, Taylor A, Freeman M, Yang Y.

Hum Mol Genet. 2013 May 15;22(10):2041-54. doi: 10.1093/hmg/ddt055. Epub 2013 Feb 7.

PMID:
23396537
[PubMed - indexed for MEDLINE]
Free PMC Article

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