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Results: 1 to 20 of 125

1.

TLR7 is involved in sequence-specific sensing of single-stranded RNAs in human macrophages.

Gantier MP, Tong S, Behlke MA, Xu D, Phipps S, Foster PS, Williams BR.

J Immunol. 2008 Feb 15;180(4):2117-24.

PMID:
18250417
[PubMed - indexed for MEDLINE]
Free Article
2.

Identification of RNA sequence motifs stimulating sequence-specific TLR8-dependent immune responses.

Forsbach A, Nemorin JG, Montino C, Müller C, Samulowitz U, Vicari AP, Jurk M, Mutwiri GK, Krieg AM, Lipford GB, Vollmer J.

J Immunol. 2008 Mar 15;180(6):3729-38.

PMID:
18322178
[PubMed - indexed for MEDLINE]
Free Article
3.

Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8.

Sarvestani ST, Tate MD, Moffat JM, Jacobi AM, Behlke MA, Miller AR, Beckham SA, McCoy CE, Chen W, Mintern JD, O'Keeffe M, John M, Williams BR, Gantier MP.

J Virol. 2014 Jan;88(2):799-810. doi: 10.1128/JVI.01571-13. Epub 2013 Nov 13.

PMID:
24227841
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Synthesis and immunological activities of novel Toll-like receptor 7 and 8 agonists.

Kandimalla ER, Struthers M, Bett AJ, Wisniewski T, Dubey SA, Jiang W, Precopio M, Sun Z, Wang H, Lan T, Agrawal S, Casimiro DR.

Cell Immunol. 2011;270(2):126-34. doi: 10.1016/j.cellimm.2011.03.027. Epub 2011 Apr 22.

PMID:
21570062
[PubMed - indexed for MEDLINE]
5.

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8.

Heil F, Hemmi H, Hochrein H, Ampenberger F, Kirschning C, Akira S, Lipford G, Wagner H, Bauer S.

Science. 2004 Mar 5;303(5663):1526-9. Epub 2004 Feb 19.

PMID:
14976262
[PubMed - indexed for MEDLINE]
Free Article
6.

Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8.

Lan T, Kandimalla ER, Yu D, Bhagat L, Li Y, Wang D, Zhu F, Tang JX, Putta MR, Cong Y, Trombino AF, Sullivan T, Agrawal S.

Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13750-5. Epub 2007 Aug 14.

PMID:
17698957
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Toll-like receptor 7 selective synthetic oligoribonucleotide agonists: synthesis and structure-activity relationship studies.

Lan T, Dai M, Wang D, Zhu FG, Kandimalla ER, Agrawal S.

J Med Chem. 2009 Nov 12;52(21):6871-9. doi: 10.1021/jm901145s.

PMID:
19824640
[PubMed - indexed for MEDLINE]
8.

In vitro-generated viral double-stranded RNA in contrast to polyinosinic:polycytidylic acid induces interferon-alpha in human plasmacytoid dendritic cells.

Löseke S, Grage-Griebenow E, Heine H, Wagner A, Akira S, Bauer S, Bufe A.

Scand J Immunol. 2006 Apr;63(4):264-74.

PMID:
16623926
[PubMed - indexed for MEDLINE]
9.

Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.

Gorden KB, Gorski KS, Gibson SJ, Kedl RM, Kieper WC, Qiu X, Tomai MA, Alkan SS, Vasilakos JP.

J Immunol. 2005 Feb 1;174(3):1259-68.

PMID:
15661881
[PubMed - indexed for MEDLINE]
Free Article
10.

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7.

Hornung V, Guenthner-Biller M, Bourquin C, Ablasser A, Schlee M, Uematsu S, Noronha A, Manoharan M, Akira S, de Fougerolles A, Endres S, Hartmann G.

Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20.

PMID:
15723075
[PubMed - indexed for MEDLINE]
11.

CD14+ cells are required for IL-12 response in bovine blood mononuclear cells activated with Toll-like receptor (TLR) 7 and TLR8 ligands.

Buza J, Benjamin P, Zhu J, Wilson HL, Lipford G, Krieg AM, Babiuk LA, Mutwiri GK.

Vet Immunol Immunopathol. 2008 Dec 15;126(3-4):273-82. doi: 10.1016/j.vetimm.2008.08.001. Epub 2008 Aug 20.

PMID:
18789542
[PubMed - indexed for MEDLINE]
12.

Immunostimulatory RNA oligonucleotides induce an effective antitumoral NK cell response through the TLR7.

Bourquin C, Schmidt L, Lanz AL, Storch B, Wurzenberger C, Anz D, Sandholzer N, Mocikat R, Berger M, Poeck H, Hartmann G, Hornung V, Endres S.

J Immunol. 2009 Nov 15;183(10):6078-86. doi: 10.4049/jimmunol.0901594.

PMID:
19890064
[PubMed - indexed for MEDLINE]
Free Article
13.

Nuclear factor kappaB (NF-kappaB) activation primes cells to a pro-inflammatory polarized response to a Toll-like receptor 7 (TLR7) agonist.

Lee J, Hayashi M, Lo JF, Fearns C, Chu WM, Luo Y, Xiang R, Chuang TH.

Biochem J. 2009 Jun 26;421(2):301-10. doi: 10.1042/BJ20090013.

PMID:
19426145
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Particle size and activation threshold: a new dimension of danger signaling.

Rettig L, Haen SP, Bittermann AG, von Boehmer L, Curioni A, Krämer SD, Knuth A, Pascolo S.

Blood. 2010 Jun 3;115(22):4533-41. doi: 10.1182/blood-2009-11-247817. Epub 2010 Mar 19.

PMID:
20304804
[PubMed - indexed for MEDLINE]
Free Article
15.

Flavivirus activation of plasmacytoid dendritic cells delineates key elements of TLR7 signaling beyond endosomal recognition.

Wang JP, Liu P, Latz E, Golenbock DT, Finberg RW, Libraty DH.

J Immunol. 2006 Nov 15;177(10):7114-21.

PMID:
17082628
[PubMed - indexed for MEDLINE]
Free Article
16.

2'-O-methyl-modified RNAs act as TLR7 antagonists.

Robbins M, Judge A, Liang L, McClintock K, Yaworski E, MacLachlan I.

Mol Ther. 2007 Sep;15(9):1663-9. Epub 2007 Jun 19.

PMID:
17579574
[PubMed - indexed for MEDLINE]
17.

RNA recognition via TLR7 and TLR8.

Hornung V, Barchet W, Schlee M, Hartmann G.

Handb Exp Pharmacol. 2008;(183):71-86. Review.

PMID:
18071655
[PubMed - indexed for MEDLINE]
18.

Exhaustive exercise reduces TNF-α and IFN-α production in response to R-848 via toll-like receptor 7 in mice.

Yano H, Uchida M, Nakai R, Ishida K, Kato Y, Kawanishi N, Shiva D.

Eur J Appl Physiol. 2010 Nov;110(4):797-803. doi: 10.1007/s00421-010-1560-1. Epub 2010 Jul 3.

PMID:
20602110
[PubMed - indexed for MEDLINE]
19.

IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation.

Zhang X, Jin J, Tang Y, Speer D, Sujkowska D, Markovic-Plese S.

J Immunol. 2009 Mar 15;182(6):3928-36. doi: 10.4049/jimmunol.0802226.

PMID:
19265172
[PubMed - indexed for MEDLINE]
Free Article
20.

Determinants of cytokine induction by small interfering RNA in human peripheral blood mononuclear cells.

Zamanian-Daryoush M, Marques JT, Gantier MP, Behlke MA, John M, Rayman P, Finke J, Williams BR.

J Interferon Cytokine Res. 2008 Apr;28(4):221-33. doi: 10.1089/jir.2007.0090.

PMID:
18439100
[PubMed - indexed for MEDLINE]

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