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Results: 1 to 20 of 1192

1.

Down-regulation of mcl-1 by small interfering RNA sensitizes resistant melanoma cells to fas-mediated apoptosis.

Chetoui N, Sylla K, Gagnon-Houde JV, Alcaide-Loridan C, Charron D, Al-Daccak R, Aoudjit F.

Mol Cancer Res. 2008 Jan;6(1):42-52. doi: 10.1158/1541-7786.MCR-07-0080.

PMID:
18234961
[PubMed - indexed for MEDLINE]
Free Article
2.

Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis.

Jiang CC, Chen LH, Gillespie S, Wang YF, Kiejda KA, Zhang XD, Hersey P.

Cancer Res. 2007 Oct 15;67(20):9750-61.

PMID:
17942905
[PubMed - indexed for MEDLINE]
Free Article
3.

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.

Longo PG, Laurenti L, Gobessi S, Sica S, Leone G, Efremov DG.

Blood. 2008 Jan 15;111(2):846-55. Epub 2007 Oct 10.

PMID:
17928528
[PubMed - indexed for MEDLINE]
Free Article
4.

Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.

Jazirehi AR, Vega MI, Chatterjee D, Goodglick L, Bonavida B.

Cancer Res. 2004 Oct 1;64(19):7117-26.

PMID:
15466208
[PubMed - indexed for MEDLINE]
Free Article
5.

Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress.

Jiang CC, Lucas K, Avery-Kiejda KA, Wade M, deBock CE, Thorne RF, Allen J, Hersey P, Zhang XD.

Cancer Res. 2008 Aug 15;68(16):6708-17. doi: 10.1158/0008-5472.CAN-08-0349.

PMID:
18701495
[PubMed - indexed for MEDLINE]
Free Article
6.

Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.

Geller J, Petak I, Szucs KS, Nagy K, Tillman DM, Houghton JA.

Clin Cancer Res. 2003 Dec 15;9(17):6504-15.

PMID:
14695155
[PubMed - indexed for MEDLINE]
Free Article
7.

Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.

Yip-Schneider MT, Klein PJ, Wentz SC, Zeni A, Menze A, Schmidt CM.

J Pharmacol Exp Ther. 2009 Jun;329(3):1063-70. doi: 10.1124/jpet.108.147306. Epub 2009 Mar 3.

PMID:
19258520
[PubMed - indexed for MEDLINE]
Free Article
8.
9.

alpha-TEA inhibits survival and enhances death pathways in cisplatin sensitive and resistant human ovarian cancer cells.

Yu W, Shun MC, Anderson K, Chen H, Sanders BG, Kline K.

Apoptosis. 2006 Oct;11(10):1813-23.

PMID:
16850165
[PubMed - indexed for MEDLINE]
10.

Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma.

Kunz M, Ibrahim S, Koczan D, Thiesen HJ, Köhler HJ, Acker T, Plate KH, Ludwig S, Rapp UR, Bröcker EB, van Muijen GN, Flory E, Gross G.

Cell Growth Differ. 2001 Mar;12(3):137-45.

PMID:
11306514
[PubMed - indexed for MEDLINE]
Free Article
12.

HLA-DR signaling inhibits Fas-mediated apoptosis in A375 melanoma cells.

Aoudjit F, Guo W, Gagnon-Houde JV, Castaigne JG, Alcaide-Loridan C, Charron D, Al-Daccak R.

Exp Cell Res. 2004 Sep 10;299(1):79-90.

PMID:
15302575
[PubMed - indexed for MEDLINE]
15.

A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.

Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS.

Cancer Res. 2006 Dec 1;66(23):11348-59.

PMID:
17145881
[PubMed - indexed for MEDLINE]
Free Article
16.

Role of RAF/MEK/ERK pathway, p-STAT-3 and Mcl-1 in sorafenib activity in human pancreatic cancer cell lines.

Ulivi P, Arienti C, Amadori D, Fabbri F, Carloni S, Tesei A, Vannini I, Silvestrini R, Zoli W.

J Cell Physiol. 2009 Jul;220(1):214-21. doi: 10.1002/jcp.21753.

PMID:
19288493
[PubMed - indexed for MEDLINE]
17.

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

Wang YF, Jiang CC, Kiejda KA, Gillespie S, Zhang XD, Hersey P.

Clin Cancer Res. 2007 Aug 15;13(16):4934-42. Epub 2007 Jul 25.

PMID:
17652623
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

Bcl-2 protects endothelial cells against gamma-radiation via a Raf-MEK-ERK-survivin signaling pathway that is independent of cytochrome c release.

Kumar P, Coltas IK, Kumar B, Chepeha DB, Bradford CR, Polverini PJ.

Cancer Res. 2007 Feb 1;67(3):1193-202.

PMID:
17283155
[PubMed - indexed for MEDLINE]
Free Article
20.

XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer.

Yu LF, Wang J, Zou B, Lin MC, Wu YL, Xia HH, Sun YW, Gu Q, He H, Lam SK, Kung HF, Wong BC.

Cancer. 2007 May 15;109(10):1996-2003.

PMID:
17385215
[PubMed - indexed for MEDLINE]
Free Article
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