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Results: 1 to 20 of 99

1.

Mutations in the zinc finger domain of IKK gamma block the activation of NF-kappa B and the induction of IL-2 in stimulated T lymphocytes.

Shifera AS, Horwitz MS.

Mol Immunol. 2008 Mar;45(6):1633-45. doi: 10.1016/j.molimm.2007.09.036. Epub 2008 Jan 22.

PMID:
18207244
[PubMed - indexed for MEDLINE]
2.
3.

The zinc finger domain of IKKγ (NEMO) protein in health and disease.

Shifera AS.

J Cell Mol Med. 2010 Oct;14(10):2404-14. doi: 10.1111/j.1582-4934.2010.01054.x. Review.

PMID:
20345847
[PubMed - indexed for MEDLINE]
4.

A point mutation in NEMO associated with anhidrotic ectodermal dysplasia with immunodeficiency pathology results in destabilization of the oligomer and reduces lipopolysaccharide- and tumor necrosis factor-mediated NF-kappa B activation.

Vinolo E, Sebban H, Chaffotte A, Israël A, Courtois G, Véron M, Agou F.

J Biol Chem. 2006 Mar 10;281(10):6334-48. Epub 2005 Dec 26.

PMID:
16379012
[PubMed - indexed for MEDLINE]
Free Article
5.

Protein kinase Calpha (PKCalpha) acts upstream of PKCtheta to activate IkappaB kinase and NF-kappaB in T lymphocytes.

Trushin SA, Pennington KN, Carmona EM, Asin S, Savoy DN, Billadeau DD, Paya CV.

Mol Cell Biol. 2003 Oct;23(19):7068-81.

PMID:
12972622
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Two-sided ubiquitin binding of NF-κB essential modulator (NEMO) zinc finger unveiled by a mutation associated with anhidrotic ectodermal dysplasia with immunodeficiency syndrome.

Ngadjeua F, Chiaravalli J, Traincard F, Raynal B, Fontan E, Agou F.

J Biol Chem. 2013 Nov 22;288(47):33722-37. doi: 10.1074/jbc.M113.483305. Epub 2013 Oct 7.

PMID:
24100029
[PubMed - indexed for MEDLINE]
7.

Somatic mutagenesis studies of NF-kappa B signaling in human T cells: evidence for an essential role of IKK gamma in NF-kappa B activation by T-cell costimulatory signals and HTLV-I Tax protein.

Harhaj EW, Good L, Xiao G, Uhlik M, Cvijic ME, Rivera-Walsh I, Sun SC.

Oncogene. 2000 Mar 9;19(11):1448-56.

PMID:
10723136
[PubMed - indexed for MEDLINE]
Free Article
8.

Activation of NF-κB and respiratory burst following Aspergillus fumigatus stimulation of macrophages.

Sun H, Xu XY, Tian XL, Shao HT, Wu XD, Wang Q, Su X, Shi Y.

Immunobiology. 2014 Jan;219(1):25-36. doi: 10.1016/j.imbio.2013.06.013. Epub 2013 Jul 4.

PMID:
23886693
[PubMed - indexed for MEDLINE]
9.

The zinc finger domain of NEMO is selectively required for NF-kappa B activation by UV radiation and topoisomerase inhibitors.

Huang TT, Feinberg SL, Suryanarayanan S, Miyamoto S.

Mol Cell Biol. 2002 Aug;22(16):5813-25.

PMID:
12138192
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A hypermorphic IkappaBalpha mutation is associated with autosomal dominant anhidrotic ectodermal dysplasia and T cell immunodeficiency.

Courtois G, Smahi A, Reichenbach J, Döffinger R, Cancrini C, Bonnet M, Puel A, Chable-Bessia C, Yamaoka S, Feinberg J, Dupuis-Girod S, Bodemer C, Livadiotti S, Novelli F, Rossi P, Fischer A, Israël A, Munnich A, Le Deist F, Casanova JL.

J Clin Invest. 2003 Oct;112(7):1108-15.

PMID:
14523047
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The carboxyl-terminal region of IkappaB kinase gamma (IKKgamma) is required for full IKK activation.

Makris C, Roberts JL, Karin M.

Mol Cell Biol. 2002 Sep;22(18):6573-81.

PMID:
12192055
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Primary human CD4+ T cells contain heterogeneous I kappa B kinase complexes: role in activation of the IL-2 promoter.

Khoshnan A, Kempiak SJ, Bennett BL, Bae D, Xu W, Manning AM, June CH, Nel AE.

J Immunol. 1999 Nov 15;163(10):5444-52.

PMID:
10553070
[PubMed - indexed for MEDLINE]
Free Article
13.

Activation of I-kappaB kinase by the HTLV type 1 Tax protein: mechanistic insights into the adaptor function of IKKgamma.

Sun SC, Harhaj EW, Xiao G, Good L.

AIDS Res Hum Retroviruses. 2000 Nov 1;16(16):1591-6. Review.

PMID:
11080796
[PubMed - indexed for MEDLINE]
14.

A novel X-linked disorder of immune deficiency and hypohidrotic ectodermal dysplasia is allelic to incontinentia pigmenti and due to mutations in IKK-gamma (NEMO).

Zonana J, Elder ME, Schneider LC, Orlow SJ, Moss C, Golabi M, Shapira SK, Farndon PA, Wara DW, Emmal SA, Ferguson BM.

Am J Hum Genet. 2000 Dec;67(6):1555-62. Epub 2000 Oct 24.

PMID:
11047757
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

T cell receptor-induced lipid raft recruitment of the I kappa B kinase complex is necessary and sufficient for NF-kappa B activation occurring in the cytosol.

Sebald A, Mattioli I, Schmitz ML.

Eur J Immunol. 2005 Jan;35(1):318-25.

PMID:
15597322
[PubMed - indexed for MEDLINE]
16.

IKK gamma (NEMO) is involved in the coordination of the AP-1 and NF-kappa B pathways.

Shifera AS, Friedman JM, Horwitz MS.

Mol Cell Biochem. 2008 Mar;310(1-2):181-90. Epub 2007 Dec 16.

PMID:
18080803
[PubMed - indexed for MEDLINE]
17.

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha.

Tang ED, Wang CY, Xiong Y, Guan KL.

J Biol Chem. 2003 Sep 26;278(39):37297-305. Epub 2003 Jul 16.

PMID:
12867425
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulation and function of IKK and IKK-related kinases.

Häcker H, Karin M.

Sci STKE. 2006 Oct 17;2006(357):re13. Review.

PMID:
17047224
[PubMed - indexed for MEDLINE]
19.

Deficient natural killer cell cytotoxicity in patients with IKK-gamma/NEMO mutations.

Orange JS, Brodeur SR, Jain A, Bonilla FA, Schneider LC, Kretschmer R, Nurko S, Rasmussen WL, Köhler JR, Gellis SE, Ferguson BM, Strominger JL, Zonana J, Ramesh N, Ballas ZK, Geha RS.

J Clin Invest. 2002 Jun;109(11):1501-9.

PMID:
12045264
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Immunosuppressive activity of endovanilloids: N-arachidonoyl-dopamine inhibits activation of the NF-kappa B, NFAT, and activator protein 1 signaling pathways.

Sancho R, Macho A, de La Vega L, Calzado MA, Fiebich BL, Appendino G, Muñoz E.

J Immunol. 2004 Feb 15;172(4):2341-51.

PMID:
14764703
[PubMed - indexed for MEDLINE]
Free Article

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