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Items: 1 to 20 of 254

1.

Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

Muik M, Frischauf I, Derler I, Fahrner M, Bergsmann J, Eder P, Schindl R, Hesch C, Polzinger B, Fritsch R, Kahr H, Madl J, Gruber H, Groschner K, Romanin C.

J Biol Chem. 2008 Mar 21;283(12):8014-22. doi: 10.1074/jbc.M708898200. Epub 2008 Jan 10.

2.

Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant.

Frischauf I, Muik M, Derler I, Bergsmann J, Fahrner M, Schindl R, Groschner K, Romanin C.

J Biol Chem. 2009 Aug 7;284(32):21696-706. doi: 10.1074/jbc.M109.018408. Epub 2009 Jun 8.

3.

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels.

Muik M, Fahrner M, Derler I, Schindl R, Bergsmann J, Frischauf I, Groschner K, Romanin C.

J Biol Chem. 2009 Mar 27;284(13):8421-6. doi: 10.1074/jbc.C800229200. Epub 2009 Feb 3.

4.

Mapping the interacting domains of STIM1 and Orai1 in Ca2+ release-activated Ca2+ channel activation.

Li Z, Lu J, Xu P, Xie X, Chen L, Xu T.

J Biol Chem. 2007 Oct 5;282(40):29448-56. Epub 2007 Aug 16.

5.

Voltage gating at the selectivity filter of the Ca2+ release-activated Ca2+ channel induced by mutation of the Orai1 protein.

Spassova MA, Hewavitharana T, Fandino RA, Kaya A, Tanaka J, Gill DL.

J Biol Chem. 2008 May 30;283(22):14938-45. Epub 2007 Dec 20.

6.

Mechanism of different spatial distributions of Caenorhabditis elegans and human STIM1 at resting state.

Gao S, Fan Y, Chen L, Lu J, Xu T, Xu P.

Cell Calcium. 2009 Jan;45(1):77-88. doi: 10.1016/j.ceca.2008.06.005. Epub 2008 Jul 29.

PMID:
18667236
7.

A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1.

Calloway N, Holowka D, Baird B.

Biochemistry. 2010 Feb 16;49(6):1067-71. doi: 10.1021/bi901936q.

8.

Mechanistic view on domains mediating STIM1-Orai coupling.

Fahrner M, Muik M, Derler I, Schindl R, Fritsch R, Frischauf I, Romanin C.

Immunol Rev. 2009 Sep;231(1):99-112. doi: 10.1111/j.1600-065X.2009.00815.x. Review.

PMID:
19754892
9.

The STIM/Orai coupling machinery.

Frischauf I, Schindl R, Derler I, Bergsmann J, Fahrner M, Romanin C.

Channels (Austin). 2008 Jul-Aug;2(4):261-8. Epub 2008 Jul 21. Review.

PMID:
18769136
10.

Orai1 and STIM reconstitute store-operated calcium channel function.

Soboloff J, Spassova MA, Tang XD, Hewavitharana T, Xu W, Gill DL.

J Biol Chem. 2006 Jul 28;281(30):20661-5. Epub 2006 Jun 9.

11.

Biochemical and functional characterization of Orai proteins.

Gwack Y, Srikanth S, Feske S, Cruz-Guilloty F, Oh-hora M, Neems DS, Hogan PG, Rao A.

J Biol Chem. 2007 Jun 1;282(22):16232-43. Epub 2007 Feb 9.

12.

Differential roles of the C and N termini of Orai1 protein in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation.

Zheng H, Zhou MH, Hu C, Kuo E, Peng X, Hu J, Kuo L, Zhang SL.

J Biol Chem. 2013 Apr 19;288(16):11263-72. doi: 10.1074/jbc.M113.450254. Epub 2013 Feb 27.

13.

A Ca2(+ )release-activated Ca2(+) (CRAC) modulatory domain (CMD) within STIM1 mediates fast Ca2(+)-dependent inactivation of ORAI1 channels.

Derler I, Fahrner M, Muik M, Lackner B, Schindl R, Groschner K, Romanin C.

J Biol Chem. 2009 Sep 11;284(37):24933-8. doi: 10.1074/jbc.C109.024083. Epub 2009 Jul 21.

14.

A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1).

Fahrner M, Muik M, Schindl R, Butorac C, Stathopulos P, Zheng L, Jardin I, Ikura M, Romanin C.

J Biol Chem. 2014 Nov 28;289(48):33231-44. doi: 10.1074/jbc.M114.610022. Epub 2014 Oct 23.

15.

Biochemical properties and cellular localisation of STIM proteins.

Dziadek MA, Johnstone LS.

Cell Calcium. 2007 Aug;42(2):123-32. Epub 2007 Mar 26. Review.

PMID:
17382385
16.

Amplification of CRAC current by STIM1 and CRACM1 (Orai1).

Peinelt C, Vig M, Koomoa DL, Beck A, Nadler MJ, Koblan-Huberson M, Lis A, Fleig A, Penner R, Kinet JP.

Nat Cell Biol. 2006 Jul;8(7):771-3. Epub 2006 May 30.

PMID:
16733527
17.

Dominant role of Orai1 with STIM1 on the cytosolic entry and cytotoxicity of lead ions.

Chiu TY, Teng HC, Huang PC, Kao FJ, Yang DM.

Toxicol Sci. 2009 Aug;110(2):353-62. doi: 10.1093/toxsci/kfp099. Epub 2009 May 8.

18.

Dynamic interaction of hTRPC6 with the Orai1-STIM1 complex or hTRPC3 mediates its role in capacitative or non-capacitative Ca(2+) entry pathways.

Jardin I, Gómez LJ, Salido GM, Rosado JA.

Biochem J. 2009 May 13;420(2):267-76. doi: 10.1042/BJ20082179.

PMID:
19260825
19.

Intramolecular shielding maintains the ER Ca²⁺ sensor STIM1 in an inactive conformation.

Yu F, Sun L, Hubrack S, Selvaraj S, Machaca K.

J Cell Sci. 2013 Jun 1;126(Pt 11):2401-10. doi: 10.1242/jcs.117200. Epub 2013 Apr 9.

20.

Missense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activation.

Maus M, Jairaman A, Stathopulos PB, Muik M, Fahrner M, Weidinger C, Benson M, Fuchs S, Ehl S, Romanin C, Ikura M, Prakriya M, Feske S.

Proc Natl Acad Sci U S A. 2015 May 12;112(19):6206-11. doi: 10.1073/pnas.1418852112. Epub 2015 Apr 27.

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