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Results: 1 to 20 of 116

1.

Elastin haploinsufficiency induces alternative aging processes in the aorta.

Pezet M, Jacob MP, Escoubet B, Gheduzzi D, Tillet E, Perret P, Huber P, Quaglino D, Vranckx R, Li DY, Starcher B, Boyle WA, Mecham RP, Faury G.

Rejuvenation Res. 2008 Feb;11(1):97-112. doi: 10.1089/rej.2007.0587.

PMID:
18173368
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Effects of elastin haploinsufficiency on the mechanical behavior of mouse arteries.

Wagenseil JE, Nerurkar NL, Knutsen RH, Okamoto RJ, Li DY, Mecham RP.

Am J Physiol Heart Circ Physiol. 2005 Sep;289(3):H1209-17. Epub 2005 Apr 29.

PMID:
15863465
[PubMed - indexed for MEDLINE]
Free Article
3.

Reduced vessel elasticity alters cardiovascular structure and function in newborn mice.

Wagenseil JE, Ciliberto CH, Knutsen RH, Levy MA, Kovacs A, Mecham RP.

Circ Res. 2009 May 22;104(10):1217-24. doi: 10.1161/CIRCRESAHA.108.192054. Epub 2009 Apr 16.

PMID:
19372465
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

[Elastin and microfibrils in vascular development and ageing: complementary or opposite roles?].

Fhayli W, Ghandour Z, Mariko B, Pezet M, Faury G.

Biol Aujourdhui. 2012;206(2):87-102. doi: 10.1051/jbio/2012009. Epub 2012 Jul 4. Review. French.

PMID:
22748047
[PubMed - indexed for MEDLINE]
5.

Developmental adaptation of the mouse cardiovascular system to elastin haploinsufficiency.

Faury G, Pezet M, Knutsen RH, Boyle WA, Heximer SP, McLean SE, Minkes RK, Blumer KJ, Kovacs A, Kelly DP, Li DY, Starcher B, Mecham RP.

J Clin Invest. 2003 Nov;112(9):1419-28.

PMID:
14597767
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Novel arterial pathology in mice and humans hemizygous for elastin.

Li DY, Faury G, Taylor DG, Davis EC, Boyle WA, Mecham RP, Stenzel P, Boak B, Keating MT.

J Clin Invest. 1998 Nov 15;102(10):1783-7.

PMID:
9819363
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Rapamycin inhibits smooth muscle cell proliferation and obstructive arteriopathy attributable to elastin deficiency.

Li W, Li Q, Qin L, Ali R, Qyang Y, Tassabehji M, Pober BR, Sessa WC, Giordano FJ, Tellides G.

Arterioscler Thromb Vasc Biol. 2013 May;33(5):1028-35. doi: 10.1161/ATVBAHA.112.300407. Epub 2013 Mar 14.

PMID:
23493289
[PubMed - indexed for MEDLINE]
Free Article
8.

Genetic modifiers of cardiovascular phenotype caused by elastin haploinsufficiency act by extrinsic noncomplementation.

Kozel BA, Knutsen RH, Ye L, Ciliberto CH, Broekelmann TJ, Mecham RP.

J Biol Chem. 2011 Dec 30;286(52):44926-36. doi: 10.1074/jbc.M111.274779. Epub 2011 Nov 2.

PMID:
22049077
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The importance of elastin to aortic development in mice.

Wagenseil JE, Ciliberto CH, Knutsen RH, Levy MA, Kovacs A, Mecham RP.

Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H257-64. doi: 10.1152/ajpheart.00194.2010. Epub 2010 May 21.

PMID:
20495146
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Discrete contributions of elastic fiber components to arterial development and mechanical compliance.

Carta L, Wagenseil JE, Knutsen RH, Mariko B, Faury G, Davis EC, Starcher B, Mecham RP, Ramirez F.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2083-9. doi: 10.1161/ATVBAHA.109.193227. Epub 2009 Oct 22.

PMID:
19850904
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Elastin-insufficient mice show normal cardiovascular remodeling in 2K1C hypertension despite higher baseline pressure and unique cardiovascular architecture.

Wagenseil JE, Knutsen RH, Li DY, Mecham RP.

Am J Physiol Heart Circ Physiol. 2007 Jul;293(1):H574-82. Epub 2007 Mar 30.

PMID:
17400710
[PubMed - indexed for MEDLINE]
Free Article
12.

Decreased aortic diameter and compliance precedes blood pressure increases in postnatal development of elastin-insufficient mice.

Le VP, Knutsen RH, Mecham RP, Wagenseil JE.

Am J Physiol Heart Circ Physiol. 2011 Jul;301(1):H221-9. doi: 10.1152/ajpheart.00119.2011. Epub 2011 May 2.

PMID:
21536846
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A fiber-based constitutive model predicts changes in amount and organization of matrix proteins with development and disease in the mouse aorta.

Cheng JK, Stoilov I, Mecham RP, Wagenseil JE.

Biomech Model Mechanobiol. 2013 Jun;12(3):497-510. doi: 10.1007/s10237-012-0420-9. Epub 2012 Jul 12.

PMID:
22790326
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Elastin haploinsufficiency results in progressive aortic valve malformation and latent valve disease in a mouse model.

Hinton RB, Adelman-Brown J, Witt S, Krishnamurthy VK, Osinska H, Sakthivel B, James JF, Li DY, Narmoneva DA, Mecham RP, Benson DW.

Circ Res. 2010 Aug 20;107(4):549-57. doi: 10.1161/CIRCRESAHA.110.221358. Epub 2010 Jun 24.

PMID:
20576933
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Fibrillin-1 genetic deficiency leads to pathological ageing of arteries in mice.

Mariko B, Pezet M, Escoubet B, Bouillot S, Andrieu JP, Starcher B, Quaglino D, Jacob MP, Huber P, Ramirez F, Faury G.

J Pathol. 2011 May;224(1):33-44. doi: 10.1002/path.2840. Epub 2011 Mar 22.

PMID:
21432852
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Differential expression of lysyl oxidases LOXL1 and LOX during growth and aging suggests specific roles in elastin and collagen fiber remodeling in rat aorta.

Behmoaras J, Slove S, Seve S, Vranckx R, Sommer P, Jacob MP.

Rejuvenation Res. 2008 Oct;11(5):883-9. doi: 10.1089/rej.2008.0760.

PMID:
18803461
[PubMed - indexed for MEDLINE]
17.

Murray's Law in elastin haploinsufficient (Eln+/-) and wild-type (WT) mice.

Sather BA, Hageman D, Wagenseil JE.

J Biomech Eng. 2012 Dec;134(12):124504. doi: 10.1115/1.4023093.

PMID:
23363211
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Induced chromosome deletion in a Williams-Beuren syndrome mouse model causes cardiovascular abnormalities.

Goergen CJ, Li HH, Francke U, Taylor CA.

J Vasc Res. 2011;48(2):119-29. doi: 10.1159/000316808. Epub 2010 Oct 7.

PMID:
20926892
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Evidence for heterozygous abnormalities of the elastin gene (ELN) affecting the quantity of vocal fold elastic fibers: a pilot study.

Watts CR, Knutsen RH, Ciliberto C, Mecham RP.

J Voice. 2011 Mar;25(2):e85-90. doi: 10.1016/j.jvoice.2010.04.006. Epub 2010 Oct 6.

PMID:
20926252
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Supravalvular aortic stenosis: elastin arteriopathy.

Merla G, Brunetti-Pierri N, Piccolo P, Micale L, Loviglio MN.

Circ Cardiovasc Genet. 2012 Dec;5(6):692-6. doi: 10.1161/CIRCGENETICS.112.962860. Review.

PMID:
23250899
[PubMed - indexed for MEDLINE]
Free Article

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