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Items: 1 to 20 of 103

1.

Antidiabetogenic effects of chromium mitigate hyperinsulinemia-induced cellular insulin resistance via correction of plasma membrane cholesterol imbalance.

Horvath EM, Tackett L, McCarthy AM, Raman P, Brozinick JT, Elmendorf JS.

Mol Endocrinol. 2008 Apr;22(4):937-50. doi: 10.1210/me.2007-0410. Epub 2007 Dec 28. Retraction in: Mol Endocrinol. 2010 Jun;24(6):1308.

2.

Chromium enhances insulin responsiveness via AMPK.

Hoffman NJ, Penque BA, Habegger KM, Sealls W, Tackett L, Elmendorf JS.

J Nutr Biochem. 2014 May;25(5):565-72. doi: 10.1016/j.jnutbio.2014.01.007. Epub 2014 Feb 20.

3.

Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK.

Wang YQ, Yao MH.

J Nutr Biochem. 2009 Dec;20(12):982-91. doi: 10.1016/j.jnutbio.2008.09.002. Epub 2009 Feb 5.

PMID:
19195868
4.

A novel membrane-based anti-diabetic action of atorvastatin.

Horvath EM, Tackett L, Elmendorf JS.

Biochem Biophys Res Commun. 2008 Aug 8;372(4):639-43. doi: 10.1016/j.bbrc.2008.05.095. Epub 2008 Jun 2. Retraction in: Biochem Biophys Res Commun. 2010 Oct 15;401(2):319.

5.

Insulin and chromium picolinate induce translocation of CD36 to the plasma membrane through different signaling pathways in 3T3-L1 adipocytes, and with a differential functionality of the CD36.

Wang Y, Van Oort MM, Yao M, Van der Horst DJ, Rodenburg KW.

Biol Trace Elem Res. 2011 Sep;142(3):735-47. doi: 10.1007/s12011-010-8809-8. Epub 2010 Aug 19.

PMID:
20721637
6.

Evidence coupling increased hexosamine biosynthesis pathway activity to membrane cholesterol toxicity and cortical filamentous actin derangement contributing to cellular insulin resistance.

Bhonagiri P, Pattar GR, Habegger KM, McCarthy AM, Tackett L, Elmendorf JS.

Endocrinology. 2011 Sep;152(9):3373-84. doi: 10.1210/en.2011-1295. Epub 2011 Jun 28.

7.

Chromium activates glucose transporter 4 trafficking and enhances insulin-stimulated glucose transport in 3T3-L1 adipocytes via a cholesterol-dependent mechanism.

Chen G, Liu P, Pattar GR, Tackett L, Bhonagiri P, Strawbridge AB, Elmendorf JS.

Mol Endocrinol. 2006 Apr;20(4):857-70. Epub 2005 Dec 8.

PMID:
16339278
9.

Loss of cortical actin filaments in insulin-resistant skeletal muscle cells impairs GLUT4 vesicle trafficking and glucose transport.

McCarthy AM, Spisak KO, Brozinick JT, Elmendorf JS.

Am J Physiol Cell Physiol. 2006 Nov;291(5):C860-8. Epub 2006 Jun 14.

11.

AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol.

Habegger KM, Hoffman NJ, Ridenour CM, Brozinick JT, Elmendorf JS.

Endocrinology. 2012 May;153(5):2130-41. doi: 10.1210/en.2011-2099. Epub 2012 Mar 20.

12.
13.

Fat-induced membrane cholesterol accrual provokes cortical filamentous actin destabilisation and glucose transport dysfunction in skeletal muscle.

Habegger KM, Penque BA, Sealls W, Tackett L, Bell LN, Blue EK, Gallagher PJ, Sturek M, Alloosh MA, Steinberg HO, Considine RV, Elmendorf JS.

Diabetologia. 2012 Feb;55(2):457-67. doi: 10.1007/s00125-011-2334-y. Epub 2011 Oct 15.

14.

Chromium picolinate inhibits resistin secretion in insulin-resistant 3T3-L1 adipocytes via activation of amp-activated protein kinase.

Wang YQ, Dong Y, Yao MH.

Clin Exp Pharmacol Physiol. 2009 Aug;36(8):843-9. doi: 10.1111/j.1440-1681.2009.05164.x. Epub 2009 Mar 2.

PMID:
19298540
15.

Hexosamine biosynthesis pathway flux contributes to insulin resistance via altering membrane phosphatidylinositol 4,5-bisphosphate and cortical filamentous actin.

Bhonagiri P, Pattar GR, Horvath EM, Habegger KM, McCarthy AM, Elmendorf JS.

Endocrinology. 2009 Apr;150(4):1636-45. doi: 10.1210/en.2008-1102. Epub 2008 Nov 26. Corrected and republished in: Endocrinology. 2011 Sep;152(9):3373-84. Retraction in: Endocrinology. 2010 Jun;151(6):2967.

16.

Protective effect of phosphatidylinositol 4,5-bisphosphate against cortical filamentous actin loss and insulin resistance induced by sustained exposure of 3T3-L1 adipocytes to insulin.

Chen G, Raman P, Bhonagiri P, Strawbridge AB, Pattar GR, Elmendorf JS.

J Biol Chem. 2004 Sep 17;279(38):39705-9. Epub 2004 Jul 23.

17.

Hexosamine biosynthesis impairs insulin action via a cholesterolgenic response.

Penque BA, Hoggatt AM, Herring BP, Elmendorf JS.

Mol Endocrinol. 2013 Mar;27(3):536-47. doi: 10.1210/me.2012-1213. Epub 2013 Jan 11.

18.

The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle fibers and reduces insulin resistance in obese mice.

Llanos P, Contreras-Ferrat A, Georgiev T, Osorio-Fuentealba C, Espinosa A, Hidalgo J, Hidalgo C, Jaimovich E.

Am J Physiol Endocrinol Metab. 2015 Feb 15;308(4):E294-305. doi: 10.1152/ajpendo.00189.2014. Epub 2014 Dec 9.

19.

Insulin sensitising action of chromium picolinate in various experimental models of diabetes mellitus.

Shindea UA, Sharma G, Xu YJ, Dhalla NS, Goyal RK.

J Trace Elem Med Biol. 2004;18(1):23-32.

PMID:
15487760
20.
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