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Results: 1 to 20 of 157

1.

Interleukin 17-producing T helper cells and interleukin 17 orchestrate autoreactive germinal center development in autoimmune BXD2 mice.

Hsu HC, Yang P, Wang J, Wu Q, Myers R, Chen J, Yi J, Guentert T, Tousson A, Stanus AL, Le TV, Lorenz RG, Xu H, Kolls JK, Carter RH, Chaplin DD, Williams RW, Mountz JD.

Nat Immunol. 2008 Feb;9(2):166-75. Epub 2007 Dec 23.

PMID:
18157131
[PubMed - indexed for MEDLINE]
2.

IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells.

Ding Y, Li J, Wu Q, Yang P, Luo B, Xie S, Druey KM, Zajac AJ, Hsu HC, Mountz JD.

J Immunol. 2013 Aug 15;191(4):1614-24. doi: 10.4049/jimmunol.1300479. Epub 2013 Jul 15.

PMID:
23858031
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH.

Immunity. 2009 Aug 21;31(2):331-41. doi: 10.1016/j.immuni.2009.08.001. Epub 2009 Aug 13.

PMID:
19682929
[PubMed - indexed for MEDLINE]
Free Article
4.

Extension of the germinal center stage of B cell development promotes autoantibodies in BXD2 mice.

Wang JH, New JS, Xie S, Yang P, Wu Q, Li J, Luo B, Ding Y, Druey KM, Hsu HC, Mountz JD.

Arthritis Rheum. 2013 Oct;65(10):2703-12. doi: 10.1002/art.38059.

PMID:
23818250
[PubMed - indexed for MEDLINE]
5.

IL-17 activates the canonical NF-kappaB signaling pathway in autoimmune B cells of BXD2 mice to upregulate the expression of regulators of G-protein signaling 16.

Xie S, Li J, Wang JH, Wu Q, Yang P, Hsu HC, Smythies LE, Mountz JD.

J Immunol. 2010 Mar 1;184(5):2289-96. doi: 10.4049/jimmunol.0903133. Epub 2010 Feb 5.

PMID:
20139273
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

IL-21 acts directly on B cells to regulate Bcl-6 expression and germinal center responses.

Linterman MA, Beaton L, Yu D, Ramiscal RR, Srivastava M, Hogan JJ, Verma NK, Smyth MJ, Rigby RJ, Vinuesa CG.

J Exp Med. 2010 Feb 15;207(2):353-63. doi: 10.1084/jem.20091738. Epub 2010 Feb 8.

PMID:
20142429
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

IL-17 drives germinal center B cells?

Tarlinton D.

Nat Immunol. 2008 Feb;9(2):124-6. doi: 10.1038/ni0208-124. No abstract available.

PMID:
18204425
[PubMed - indexed for MEDLINE]
8.

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation.

Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, McClanahan T, Kastelein RA, Cua DJ.

J Exp Med. 2005 Jan 17;201(2):233-40.

PMID:
15657292
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

ICOS-dependent extrafollicular helper T cells elicit IgG production via IL-21 in systemic autoimmunity.

Odegard JM, Marks BR, DiPlacido LD, Poholek AC, Kono DH, Dong C, Flavell RA, Craft J.

J Exp Med. 2008 Nov 24;205(12):2873-86. doi: 10.1084/jem.20080840. Epub 2008 Nov 3.

PMID:
18981236
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cytokine regulation of B-cell migratory behavior favors formation of germinal centers in autoimmune disease.

Mountz JD, Wang JH, Xie S, Hsu HC.

Discov Med. 2011 Jan;11(56):76-85. Review.

PMID:
21276413
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase.

McCausland MM, Yusuf I, Tran H, Ono N, Yanagi Y, Crotty S.

J Immunol. 2007 Jan 15;178(2):817-28.

PMID:
17202343
[PubMed - indexed for MEDLINE]
Free Article
12.

IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo.

Sonderegger I, Kisielow J, Meier R, King C, Kopf M.

Eur J Immunol. 2008 Jul;38(7):1833-8. doi: 10.1002/eji.200838511.

PMID:
18546146
[PubMed - indexed for MEDLINE]
13.

IL-21 regulates germinal center B cell differentiation and proliferation through a B cell-intrinsic mechanism.

Zotos D, Coquet JM, Zhang Y, Light A, D'Costa K, Kallies A, Corcoran LM, Godfrey DI, Toellner KM, Smyth MJ, Nutt SL, Tarlinton DM.

J Exp Med. 2010 Feb 15;207(2):365-78. doi: 10.1084/jem.20091777. Epub 2010 Feb 8.

PMID:
20142430
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A positive feedback loop of IL-21 signaling provoked by homeostatic CD4+CD25- T cell expansion is essential for the development of arthritis in autoimmune K/BxN mice.

Jang E, Cho SH, Park H, Paik DJ, Kim JM, Youn J.

J Immunol. 2009 Apr 15;182(8):4649-56. doi: 10.4049/jimmunol.0804350.

PMID:
19342640
[PubMed - indexed for MEDLINE]
Free Article
15.

Th17 cytokines and their emerging roles in inflammation and autoimmunity.

Fouser LA, Wright JF, Dunussi-Joannopoulos K, Collins M.

Immunol Rev. 2008 Dec;226:87-102. doi: 10.1111/j.1600-065X.2008.00712.x. Review.

PMID:
19161418
[PubMed - indexed for MEDLINE]
16.

The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease.

Qian Y, Liu C, Hartupee J, Altuntas CZ, Gulen MF, Jane-Wit D, Xiao J, Lu Y, Giltiay N, Liu J, Kordula T, Zhang QW, Vallance B, Swaidani S, Aronica M, Tuohy VK, Hamilton T, Li X.

Nat Immunol. 2007 Mar;8(3):247-56. Epub 2007 Feb 4.

PMID:
17277779
[PubMed - indexed for MEDLINE]
17.

The roles of IL-17A in inflammatory immune responses and host defense against pathogens.

Iwakura Y, Nakae S, Saijo S, Ishigame H.

Immunol Rev. 2008 Dec;226:57-79. doi: 10.1111/j.1600-065X.2008.00699.x. Review.

PMID:
19161416
[PubMed - indexed for MEDLINE]
18.

Regulation of gut inflammation and th17 cell response by interleukin-21.

Fina D, Sarra M, Fantini MC, Rizzo A, Caruso R, Caprioli F, Stolfi C, Cardolini I, Dottori M, Boirivant M, Pallone F, Macdonald TT, Monteleone G.

Gastroenterology. 2008 Apr;134(4):1038-48. doi: 10.1053/j.gastro.2008.01.041. Epub 2008 Jan 17.

PMID:
18395085
[PubMed - indexed for MEDLINE]
19.

In vivo expression of interleukin-8, and regulated on activation, normal, T-cell expressed, and secreted, by human germinal centre B lymphocytes.

Sims-Mourtada JC, Guzman-Rojas L, Rangel R, Nghiem DX, Ullrich SE, Guret C, Cain K, Martinez-Valdez H.

Immunology. 2003 Nov;110(3):296-303.

PMID:
14632656
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Interleukin-17 and its expanding biological functions.

Xu S, Cao X.

Cell Mol Immunol. 2010 May;7(3):164-74. doi: 10.1038/cmi.2010.21. Epub 2010 Apr 12. Review.

PMID:
20383173
[PubMed - indexed for MEDLINE]

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