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Items: 1 to 20 of 151

1.

Identification of Nrf2-dependent airway epithelial adaptive response to proinflammatory oxidant-hypochlorous acid challenge by transcription profiling.

Zhu L, Pi J, Wachi S, Andersen ME, Wu R, Chen Y.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L469-77. Epub 2007 Dec 21.

2.

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid.

Pi J, Zhang Q, Woods CG, Wong V, Collins S, Andersen ME.

Toxicol Appl Pharmacol. 2008 Feb 1;226(3):236-43. Epub 2007 Sep 26.

PMID:
17980396
3.

Dose-dependent transitions in Nrf2-mediated adaptive response and related stress responses to hypochlorous acid in mouse macrophages.

Woods CG, Fu J, Xue P, Hou Y, Pluta LJ, Yang L, Zhang Q, Thomas RS, Andersen ME, Pi J.

Toxicol Appl Pharmacol. 2009 Jul 1;238(1):27-36. doi: 10.1016/j.taap.2009.04.007. Epub 2009 Apr 17.

5.

Activation of Nrf2/ARE pathway protects endothelial cells from oxidant injury and inhibits inflammatory gene expression.

Chen XL, Dodd G, Thomas S, Zhang X, Wasserman MA, Rovin BH, Kunsch C.

Am J Physiol Heart Circ Physiol. 2006 May;290(5):H1862-70. Epub 2005 Dec 9.

6.
7.

Mechanistic studies of the Nrf2-Keap1 signaling pathway.

Zhang DD.

Drug Metab Rev. 2006;38(4):769-89. Review.

PMID:
17145701
8.

Transcriptional regulation of human carboxylesterase 1A1 by nuclear factor-erythroid 2 related factor 2 (Nrf2).

Maruichi T, Fukami T, Nakajima M, Yokoi T.

Biochem Pharmacol. 2010 Jan 15;79(2):288-95. doi: 10.1016/j.bcp.2009.08.019. Epub 2009 Aug 26.

PMID:
19715681
9.

Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.

Surh YJ, Kundu JK, Na HK.

Planta Med. 2008 Oct;74(13):1526-39. doi: 10.1055/s-0028-1088302. Epub 2008 Oct 20. Review.

PMID:
18937164
10.

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer.

Hayes JD, McMahon M.

Trends Biochem Sci. 2009 Apr;34(4):176-88. doi: 10.1016/j.tibs.2008.12.008. Epub 2009 Mar 25. Review.

PMID:
19321346
11.

Regulation of neutrophil elastase-induced MUC5AC expression by nuclear factor erythroid-2 related factor 2 in human airway epithelial cells.

Qi L, Xiangdong Z, Hongmei Y, Xiaohong N, Xiaoyan X.

J Investig Med. 2010 Jun;58(5):730-6. doi: 10.231/JIM.0b013e3181d88fde.

PMID:
20216230
12.

Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells.

Kode A, Rajendrasozhan S, Caito S, Yang SR, Megson IL, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L478-88. Epub 2007 Dec 27.

13.

Lansoprazole, a proton pump inhibitor, mediates anti-inflammatory effect in gastric mucosal cells through the induction of heme oxygenase-1 via activation of NF-E2-related factor 2 and oxidation of kelch-like ECH-associating protein 1.

Takagi T, Naito Y, Okada H, Ishii T, Mizushima K, Akagiri S, Adachi S, Handa O, Kokura S, Ichikawa H, Itoh K, Yamamoto M, Matsui H, Yoshikawa T.

J Pharmacol Exp Ther. 2009 Oct;331(1):255-64. doi: 10.1124/jpet.109.152702. Epub 2009 Jul 23.

14.

Biomechanical forces in atherosclerosis-resistant vascular regions regulate endothelial redox balance via phosphoinositol 3-kinase/Akt-dependent activation of Nrf2.

Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, Gimbrone MA Jr.

Circ Res. 2007 Sep 28;101(7):723-33. Epub 2007 Aug 2.

15.

Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes.

Karapetian RN, Evstafieva AG, Abaeva IS, Chichkova NV, Filonov GS, Rubtsov YP, Sukhacheva EA, Melnikov SV, Schneider U, Wanker EE, Vartapetian AB.

Mol Cell Biol. 2005 Feb;25(3):1089-99.

16.

Nrf2 and antioxidant defense against CYP2E1 toxicity.

Cederbaum A.

Expert Opin Drug Metab Toxicol. 2009 Oct;5(10):1223-44. doi: 10.1517/17425250903143769. Review.

PMID:
19671018
17.
18.

Kavalactones protect neural cells against amyloid beta peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation.

Wruck CJ, Götz ME, Herdegen T, Varoga D, Brandenburg LO, Pufe T.

Mol Pharmacol. 2008 Jun;73(6):1785-95. doi: 10.1124/mol.107.042499. Epub 2008 Mar 11.

19.

NRF2 as a determinant of cellular resistance in retinoic acid cytotoxicity.

Tan KP, Kosuge K, Yang M, Ito S.

Free Radic Biol Med. 2008 Dec 15;45(12):1663-73. doi: 10.1016/j.freeradbiomed.2008.09.010. Epub 2008 Sep 23.

PMID:
18845239
20.

Activation of the Nrf2/antioxidant response pathway increases IL-8 expression.

Zhang X, Chen X, Song H, Chen HZ, Rovin BH.

Eur J Immunol. 2005 Nov;35(11):3258-67.

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