Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 77

Similar articles for PubMed (Select 18073532)


The E3 ubiquitin ligase EDD regulates S-phase and G(2)/M DNA damage checkpoints.

Munoz MA, Saunders DN, Henderson MJ, Clancy JL, Russell AJ, Lehrbach G, Musgrove EA, Watts CK, Sutherland RL.

Cell Cycle. 2007 Dec 15;6(24):3070-7. Epub 2007 Sep 7.


EDD mediates DNA damage-induced activation of CHK2.

Henderson MJ, Munoz MA, Saunders DN, Clancy JL, Russell AJ, Williams B, Pappin D, Khanna KK, Jackson SP, Sutherland RL, Watts CK.

J Biol Chem. 2006 Dec 29;281(52):39990-40000. Epub 2006 Oct 30.


Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks.

Takemura H, Rao VA, Sordet O, Furuta T, Miao ZH, Meng L, Zhang H, Pommier Y.

J Biol Chem. 2006 Oct 13;281(41):30814-23. Epub 2006 Aug 10.


The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.

Castedo M, Perfettini JL, Roumier T, Yakushijin K, Horne D, Medema R, Kroemer G.

Oncogene. 2004 May 27;23(25):4353-61.


no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila.

Merkle JA, Rickmyre JL, Garg A, Loggins EB, Jodoin JN, Lee E, Wu LP, Lee LA.

Development. 2009 Feb;136(3):449-59. doi: 10.1242/dev.027599.


Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.

Singh SV, Herman-Antosiewicz A, Singh AV, Lew KL, Srivastava SK, Kamath R, Brown KD, Zhang L, Baskaran R.

J Biol Chem. 2004 Jun 11;279(24):25813-22. Epub 2004 Apr 8.


Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.

Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.

J Biol Chem. 2003 Apr 25;278(17):14806-11. Epub 2003 Feb 14.


Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.

Shang ZF, Huang B, Xu QZ, Zhang SM, Fan R, Liu XD, Wang Y, Zhou PK.

Cancer Res. 2010 May 1;70(9):3657-66. doi: 10.1158/0008-5472.CAN-09-3362. Epub 2010 Apr 20.


DNA damage during the spindle-assembly checkpoint degrades CDC25A, inhibits cyclin-CDC2 complexes, and reverses cells to interphase.

Chow JP, Siu WY, Fung TK, Chan WM, Lau A, Arooz T, Ng CP, Yamashita K, Poon RY.

Mol Biol Cell. 2003 Oct;14(10):3989-4002. Epub 2003 Jul 25.


Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.

Rainey MD, Black EJ, Zachos G, Gillespie DA.

Oncogene. 2008 Feb 7;27(7):896-906. Epub 2007 Aug 6.


The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2.

Tsvetkov LM, Tsekova RT, Xu X, Stern DF.

Cell Cycle. 2005 Apr;4(4):609-17. Epub 2005 Apr 9.


Oncogenic RAS induces accelerated transition through G2/M and promotes defects in the G2 DNA damage and mitotic spindle checkpoints.

Knauf JA, Ouyang B, Knudsen ES, Fukasawa K, Babcock G, Fagin JA.

J Biol Chem. 2006 Feb 17;281(7):3800-9. Epub 2005 Nov 29.


Dual regulation of Cdc25A by Chk1 and p53-ATF3 in DNA replication checkpoint control.

Demidova AR, Aau MY, Zhuang L, Yu Q.

J Biol Chem. 2009 Feb 13;284(7):4132-9. doi: 10.1074/jbc.M808118200. Epub 2008 Dec 7.


Critical role for mouse Hus1 in an S-phase DNA damage cell cycle checkpoint.

Weiss RS, Leder P, Vaziri C.

Mol Cell Biol. 2003 Feb;23(3):791-803.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk