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Results: 1 to 20 of 310

1.

Humanized antihuman IL-6 receptor antibody, tocilizumab.

Nishimoto N, Kishimoto T.

Handb Exp Pharmacol. 2008;(181):151-60. Review.

PMID:
18071945
[PubMed - indexed for MEDLINE]
2.

[Humanized anti-human IL-6 receptor antibody, tocilizumab].

Nishimoto N.

Nihon Rinsho. 2007 Jul;65(7):1218-25. Review. Japanese.

PMID:
17642235
[PubMed - indexed for MEDLINE]
3.

Tocilizumab inhibits signal transduction mediated by both mIL-6R and sIL-6R, but not by the receptors of other members of IL-6 cytokine family.

Mihara M, Kasutani K, Okazaki M, Nakamura A, Kawai S, Sugimoto M, Matsumoto Y, Ohsugi Y.

Int Immunopharmacol. 2005 Nov;5(12):1731-40.

PMID:
16102523
[PubMed - indexed for MEDLINE]
4.

Interleukin-6--a key mediator of systemic and local symptoms in rheumatoid arthritis.

Cronstein BN.

Bull NYU Hosp Jt Dis. 2007;65 Suppl 1:S11-5. Review.

PMID:
17708739
[PubMed - indexed for MEDLINE]
Free Article
5.

Inhibiting interleukin-6 in rheumatoid arthritis.

Choy E.

Curr Rheumatol Rep. 2008 Oct;10(5):413-7.

PMID:
18817647
[PubMed - indexed for MEDLINE]
6.

Anti-interleukin-6 receptor antibody therapy in rheumatic diseases.

Nakahara H, Nishimoto N.

Endocr Metab Immune Disord Drug Targets. 2006 Dec;6(4):373-81. Review.

PMID:
17214583
[PubMed - indexed for MEDLINE]
7.

Clinical value of blocking IL-6 receptor.

Mima T, Nishimoto N.

Curr Opin Rheumatol. 2009 May;21(3):224-30. doi: 10.1097/BOR.0b013e3283295fec. Review.

PMID:
19365268
[PubMed - indexed for MEDLINE]
8.

Interleukin-6 as a key player in systemic inflammation and joint destruction.

Fonseca JE, Santos MJ, Canhão H, Choy E.

Autoimmun Rev. 2009 Jun;8(7):538-42. doi: 10.1016/j.autrev.2009.01.012. Epub 2009 Feb 2. Review.

PMID:
19189867
[PubMed - indexed for MEDLINE]
10.

Mechanisms and pathologic significances in increase in serum interleukin-6 (IL-6) and soluble IL-6 receptor after administration of an anti-IL-6 receptor antibody, tocilizumab, in patients with rheumatoid arthritis and Castleman disease.

Nishimoto N, Terao K, Mima T, Nakahara H, Takagi N, Kakehi T.

Blood. 2008 Nov 15;112(10):3959-64. doi: 10.1182/blood-2008-05-155846. Epub 2008 Sep 10.

PMID:
18784373
[PubMed - indexed for MEDLINE]
Free Article
11.

The therapy of autoimmune diseases by anti-interleukin-6 receptor antibody.

Mihara M, Nishimoto N, Ohsugi Y.

Expert Opin Biol Ther. 2005 May;5(5):683-90. Review.

PMID:
15934843
[PubMed - indexed for MEDLINE]
12.
13.

Anti-interleukin-6 receptor antibody treatment in inflammatory autoimmune diseases.

Ding C, Jones G.

Rev Recent Clin Trials. 2006 Sep;1(3):193-200. Review.

PMID:
18473972
[PubMed - indexed for MEDLINE]
14.

Tocilizumab: blockade of interleukin-6 signaling pathway as a therapeutic strategy for inflammatory disorders.

Paul-Pletzer K.

Drugs Today (Barc). 2006 Sep;42(9):559-76. Review.

PMID:
17028666
[PubMed - indexed for MEDLINE]
15.

Interleukin-6 inhibition and clinical efficacy in rheumatoid arthritis treatment--data from randomized clinical trials.

Kavanaugh A.

Bull NYU Hosp Jt Dis. 2007;65 Suppl 1:S16-20. Review.

PMID:
17708740
[PubMed - indexed for MEDLINE]
Free Article
16.

Interleukin-6 in rheumatoid arthritis.

Nishimoto N.

Curr Opin Rheumatol. 2006 May;18(3):277-81. Review.

PMID:
16582692
[PubMed - indexed for MEDLINE]
17.

[Clinical benefits of anti-human IL-6 receptor antibody therapy].

Nishimoto N.

Clin Calcium. 2007 Apr;17(4):562-8. Review. Japanese.

PMID:
17404486
[PubMed - indexed for MEDLINE]
18.

Clinical study of tocilizumab in children with systemic-onset juvenile idiopathic arthritis.

Yokota S, Miyamae T, Imagawa T, Katakura S, Kurosawa R, Mori M.

Clin Rev Allergy Immunol. 2005 Jun;28(3):231-8. Review.

PMID:
16129907
[PubMed - indexed for MEDLINE]
19.

Clinical studies in patients with Castleman's disease, Crohn's disease, and rheumatoid arthritis in Japan.

Nishimoto N.

Clin Rev Allergy Immunol. 2005 Jun;28(3):221-30. Review.

PMID:
16129906
[PubMed - indexed for MEDLINE]
20.

[Immunotherapy using IL-6 receptor as the target].

Nishimoto N.

Nihon Rinsho Meneki Gakkai Kaishi. 2008 Oct;31(5):399-404. Review. Japanese. Erratum in: Nihon Rinsho Meneki Gakkai Kaishi. 2008 Dec;31(6):423.

PMID:
18974624
[PubMed - indexed for MEDLINE]
Free Article

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