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Items: 1 to 20 of 250

1.

The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis.

Hetfeld BK, Peth A, Sun XM, Henklein P, Cohen GM, Dubiel W.

Apoptosis. 2008 Feb;13(2):187-95.

PMID:
18060501
2.

Protection of cullin-RING E3 ligases by CSN-UBP12.

Wu JT, Chan YR, Chien CT.

Trends Cell Biol. 2006 Jul;16(7):362-9. Epub 2006 Jun 9. Review.

PMID:
16762551
3.

CAND1 enhances deneddylation of CUL1 by COP9 signalosome.

Min KW, Kwon MJ, Park HS, Park Y, Yoon SK, Yoon JB.

Biochem Biophys Res Commun. 2005 Sep 2;334(3):867-74.

PMID:
16036220
4.
5.

The COP9 signalosome inhibits p27(kip1) degradation and impedes G1-S phase progression via deneddylation of SCF Cul1.

Yang X, Menon S, Lykke-Andersen K, Tsuge T, Di Xiao, Wang X, Rodriguez-Suarez RJ, Zhang H, Wei N.

Curr Biol. 2002 Apr 16;12(8):667-72.

6.

The COP9/signalosome increases the efficiency of von Hippel-Lindau protein ubiquitin ligase-mediated hypoxia-inducible factor-alpha ubiquitination.

Miyauchi Y, Kato M, Tokunaga F, Iwai K.

J Biol Chem. 2008 Jun 13;283(24):16622-31. doi: 10.1074/jbc.M710599200. Epub 2008 Apr 18.

7.

Neddylation and deneddylation regulate Cul1 and Cul3 protein accumulation.

Wu JT, Lin HC, Hu YC, Chien CT.

Nat Cell Biol. 2005 Oct;7(10):1014-20. Epub 2005 Aug 28.

PMID:
16127432
8.

Deregulation of the COP9 signalosome-cullin-RING ubiquitin-ligase pathway: mechanisms and roles in urological cancers.

Gummlich L, Rabien A, Jung K, Dubiel W.

Int J Biochem Cell Biol. 2013 Jul;45(7):1327-37. doi: 10.1016/j.biocel.2013.03.023. Epub 2013 Apr 10. Review.

PMID:
23583660
9.

Association of SAP130/SF3b-3 with Cullin-RING ubiquitin ligase complexes and its regulation by the COP9 signalosome.

Menon S, Tsuge T, Dohmae N, Takio K, Wei N.

BMC Biochem. 2008 Jan 3;9:1. doi: 10.1186/1471-2091-9-1.

10.

The COP9 signalosome mediates beta-catenin degradation by deneddylation and blocks adenomatous polyposis coli destruction via USP15.

Huang X, Langelotz C, Hetfeld-Pechoc BK, Schwenk W, Dubiel W.

J Mol Biol. 2009 Aug 28;391(4):691-702. doi: 10.1016/j.jmb.2009.06.066. Epub 2009 Jul 1.

PMID:
19576224
11.

The COP9 signalosome counteracts the accumulation of cullin SCF ubiquitin E3 RING ligases during fungal development.

von Zeska Kress MR, Harting R, Bayram Ö, Christmann M, Irmer H, Valerius O, Schinke J, Goldman GH, Braus GH.

Mol Microbiol. 2012 Mar;83(6):1162-77. doi: 10.1111/j.1365-2958.2012.07999.x. Epub 2012 Feb 22.

PMID:
22329854
12.

The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs.

Neuss H, Huang X, Hetfeld BK, Deva R, Henklein P, Nigam S, Mall JW, Schwenk W, Dubiel W.

J Mol Med (Berl). 2007 Sep;85(9):961-70. Epub 2007 Apr 11.

PMID:
17429597
13.

The COP9 signalosome and its role in plant development.

Schwechheimer C, Isono E.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):157-62. doi: 10.1016/j.ejcb.2009.11.021. Epub 2009 Dec 24. Review.

PMID:
20036030
14.

The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae.

Kurz T, Ozlü N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M.

Nature. 2005 Jun 30;435(7046):1257-61.

PMID:
15988528
15.

Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism.

Emberley ED, Mosadeghi R, Deshaies RJ.

J Biol Chem. 2012 Aug 24;287(35):29679-89. doi: 10.1074/jbc.M112.352484. Epub 2012 Jul 5.

16.

DELLA proteins restrain germination and elongation growth in Arabidopsis thaliana COP9 signalosome mutants.

Dohmann EM, Nill C, Schwechheimer C.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):163-8. doi: 10.1016/j.ejcb.2009.12.001. Epub 2010 Jan 18.

PMID:
20083325
17.

Electron microscopy and in vitro deneddylation reveal similar architectures and biochemistry of isolated human and Flag-mouse COP9 signalosome complexes.

Rockel B, Schmaler T, Huang X, Dubiel W.

Biochem Biophys Res Commun. 2014 Jul 25;450(2):991-7. doi: 10.1016/j.bbrc.2014.06.093. Epub 2014 Jun 25.

PMID:
24973710
18.

The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1.

Hetfeld BK, Helfrich A, Kapelari B, Scheel H, Hofmann K, Guterman A, Glickman M, Schade R, Kloetzel PM, Dubiel W.

Curr Biol. 2005 Jul 12;15(13):1217-21.

19.
20.

The COP9 signalosome: an alternative lid for the 26S proteasome?

Li L, Deng XW.

Trends Cell Biol. 2003 Oct;13(10):507-9. Review.

PMID:
14507477
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