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Results: 1 to 20 of 423

1.

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas.

Gao SP, Mark KG, Leslie K, Pao W, Motoi N, Gerald WL, Travis WD, Bornmann W, Veach D, Clarkson B, Bromberg JF.

J Clin Invest. 2007 Dec;117(12):3846-56.

PMID:
18060032
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

Berishaj M, Gao SP, Ahmed S, Leslie K, Al-Ahmadie H, Gerald WL, Bornmann W, Bromberg JF.

Breast Cancer Res. 2007;9(3):R32.

PMID:
17531096
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

IL-6 involvement in epithelial cancers.

Schafer ZT, Brugge JS.

J Clin Invest. 2007 Dec;117(12):3660-3.

PMID:
18060028
[PubMed - indexed for MEDLINE]
Free PMC Article
4.
5.

Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor.

Alvarez JV, Greulich H, Sellers WR, Meyerson M, Frank DA.

Cancer Res. 2006 Mar 15;66(6):3162-8.

PMID:
16540667
[PubMed - indexed for MEDLINE]
Free Article
6.

Activation of the AKT and STAT3 pathways and prolonged survival by a mutant EGFR in human lung cancer cells.

Akca H, Tani M, Hishida T, Matsumoto S, Yokota J.

Lung Cancer. 2006 Oct;54(1):25-33. Epub 2006 Jul 26.

PMID:
16872715
[PubMed - indexed for MEDLINE]
7.

STAT3 can be activated through paracrine signaling in breast epithelial cells.

Lieblein JC, Ball S, Hutzen B, Sasser AK, Lin HJ, Huang TH, Hall BM, Lin J.

BMC Cancer. 2008 Oct 21;8:302. doi: 10.1186/1471-2407-8-302.

PMID:
18939993
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer.

Dalwadi H, Krysan K, Heuze-Vourc'h N, Dohadwala M, Elashoff D, Sharma S, Cacalano N, Lichtenstein A, Dubinett S.

Clin Cancer Res. 2005 Nov 1;11(21):7674-82.

PMID:
16278387
[PubMed - indexed for MEDLINE]
Free Article
9.

Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer.

Haura EB, Zheng Z, Song L, Cantor A, Bepler G.

Clin Cancer Res. 2005 Dec 1;11(23):8288-94.

PMID:
16322287
[PubMed - indexed for MEDLINE]
Free Article
10.

Molecular context of the EGFR mutations: evidence for the activation of mTOR/S6K signaling.

Conde E, Angulo B, Tang M, Morente M, Torres-Lanzas J, Lopez-Encuentra A, Lopez-Rios F, Sanchez-Cespedes M.

Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):710-7.

PMID:
16467080
[PubMed - indexed for MEDLINE]
Free Article
11.

Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells.

Song L, Turkson J, Karras JG, Jove R, Haura EB.

Oncogene. 2003 Jul 3;22(27):4150-65.

PMID:
12833138
[PubMed - indexed for MEDLINE]
12.

Diversity of epidermal growth factor receptor-mediated activation of downstream molecules in human lung carcinomas.

Suzuki S, Igarashi S, Hanawa M, Matsubara H, Ooi A, Dobashi Y.

Mod Pathol. 2006 Jul;19(7):986-98. Epub 2006 Apr 28.

PMID:
16648865
[PubMed - indexed for MEDLINE]
Free Article
13.

Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling.

Zimmer S, Kahl P, Buhl TM, Steiner S, Wardelmann E, Merkelbach-Bruse S, Buettner R, Heukamp LC.

J Cancer Res Clin Oncol. 2009 May;135(5):723-30. doi: 10.1007/s00432-008-0509-9. Epub 2008 Nov 11.

PMID:
19002495
[PubMed - indexed for MEDLINE]
15.

IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines.

Mejías-Luque R, Peiró S, Vincent A, Van Seuningen I, de Bolós C.

Biochim Biophys Acta. 2008 Oct;1783(10):1728-36. doi: 10.1016/j.bbamcr.2008.05.020. Epub 2008 Jun 4.

PMID:
18573283
[PubMed - indexed for MEDLINE]
Free Article
16.

Antiapoptotic activity of autocrine interleukin-22 and therapeutic effects of interleukin-22-small interfering RNA on human lung cancer xenografts.

Zhang W, Chen Y, Wei H, Zheng C, Sun R, Zhang J, Tian Z.

Clin Cancer Res. 2008 Oct 15;14(20):6432-9. doi: 10.1158/1078-0432.CCR-07-4401.

PMID:
18927282
[PubMed - indexed for MEDLINE]
Free Article
17.

STAT3 expression in activating EGFR-driven adenocarcinoma of the lung.

Takata S, Takigawa N, Segawa Y, Kubo T, Ohashi K, Kozuki T, Teramoto N, Yamashita M, Toyooka S, Tanimoto M, Kiura K.

Lung Cancer. 2012 Jan;75(1):24-9. doi: 10.1016/j.lungcan.2011.05.015.

PMID:
21684622
[PubMed - indexed for MEDLINE]
18.

JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling.

Song L, Rawal B, Nemeth JA, Haura EB.

Mol Cancer Ther. 2011 Mar;10(3):481-94. doi: 10.1158/1535-7163.MCT-10-0502. Epub 2011 Jan 7.

PMID:
21216930
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis.

Rosen DG, Mercado-Uribe I, Yang G, Bast RC Jr, Amin HM, Lai R, Liu J.

Cancer. 2006 Dec 1;107(11):2730-40.

PMID:
17063503
[PubMed - indexed for MEDLINE]
Free Article
20.

Pyridone 6, a pan-Janus-activated kinase inhibitor, induces growth inhibition of multiple myeloma cells.

Pedranzini L, Dechow T, Berishaj M, Comenzo R, Zhou P, Azare J, Bornmann W, Bromberg J.

Cancer Res. 2006 Oct 1;66(19):9714-21.

PMID:
17018630
[PubMed - indexed for MEDLINE]
Free Article
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