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Results: 1 to 20 of 325

1.
2.

A food-born heterocyclic amine, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), suppresses tumor necrosis factor-alpha expression in lipoteichoic acid-stimulated RAW 264.7 cells.

Im J, Choi HS, Kim SK, Woo SS, Ryu YH, Kang SS, Yun CH, Han SH.

Cancer Lett. 2009 Feb 8;274(1):109-17. doi: 10.1016/j.canlet.2008.09.003. Epub 2008 Oct 9.

PMID:
18845389
[PubMed - indexed for MEDLINE]
3.

Inhibition of cell death in human mammary epithelial cells by the cooked meat-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine.

Venugopal M, Agarwal R, Callaway A, Schut HA, Snyderwine EG.

Biochem Biophys Res Commun. 1999 Dec 9;266(1):203-7.

PMID:
10581190
[PubMed - indexed for MEDLINE]
4.

The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity.

Lauber SN, Ali S, Gooderham NJ.

Carcinogenesis. 2004 Dec;25(12):2509-17. Epub 2004 Aug 19.

PMID:
15319301
[PubMed - indexed for MEDLINE]
Free Article
5.

Mechanisms of action of the carcinogenic heterocyclic amine PhIP.

Gooderham NJ, Creton S, Lauber SN, Zhu H.

Toxicol Lett. 2007 Feb 5;168(3):269-77. Epub 2006 Nov 16.

PMID:
17156947
[PubMed - indexed for MEDLINE]
6.

The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells.

Lauber SN, Gooderham NJ.

Toxicology. 2011 Jan 11;279(1-3):139-45. doi: 10.1016/j.tox.2010.10.004. Epub 2010 Oct 15.

PMID:
20951759
[PubMed - indexed for MEDLINE]
7.

The dietary charred meat carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine acts as both a tumor initiator and promoter in the rat ventral prostate.

Nakai Y, Nelson WG, De Marzo AM.

Cancer Res. 2007 Feb 1;67(3):1378-84. Epub 2007 Jan 30.

PMID:
17264317
[PubMed - indexed for MEDLINE]
Free Article
8.

Responses of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) in MCF-7 cells are culture condition dependent.

Immonen E, Serpi R, Vähäkangas K, Myllynen P.

Chem Biol Interact. 2009 Nov 10;182(1):73-83. doi: 10.1016/j.cbi.2009.07.020. Epub 2009 Aug 6.

PMID:
19647730
[PubMed - indexed for MEDLINE]
9.

A mechanistic basis for the role of cycle arrest in the genetic toxicology of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

Creton S, Zhu H, Gooderham NJ.

Toxicol Sci. 2005 Apr;84(2):335-43. Epub 2005 Jan 5.

PMID:
15635149
[PubMed - indexed for MEDLINE]
Free Article
10.

2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) modulates lactogenic hormone-mediated differentiation and gene expression in HC11 mouse mammary epithelial cells.

Shan L, Rouhani SA, Schut HA, Snyderwine EG.

Cell Growth Differ. 2001 Dec;12(12):649-56.

PMID:
11751460
[PubMed - indexed for MEDLINE]
Free Article
11.

Detection of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer.

Zhu J, Chang P, Bondy ML, Sahin AA, Singletary SE, Takahashi S, Shirai T, Li D.

Cancer Epidemiol Biomarkers Prev. 2003 Sep;12(9):830-7.

PMID:
14504191
[PubMed - indexed for MEDLINE]
Free Article
12.
13.

Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

Snyderwine EG, Venugopal M, Yu M.

Mutat Res. 2002 Sep 30;506-507:145-52. Review.

PMID:
12351154
[PubMed - indexed for MEDLINE]
14.

Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.

Yang R, Piperdi S, Gorlick R.

Clin Cancer Res. 2008 Oct 15;14(20):6396-404. doi: 10.1158/1078-0432.CCR-07-5113.

PMID:
18927278
[PubMed - indexed for MEDLINE]
Free Article
16.

Molecular and genetic toxicology of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).

Gooderham NJ, Zhu H, Lauber S, Boyce A, Creton S.

Mutat Res. 2002 Sep 30;506-507:91-9. Review.

PMID:
12351148
[PubMed - indexed for MEDLINE]
17.

Genomic imbalance in rat mammary gland carcinomas induced by 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine.

Yu M, Ryu DY, Snyderwine EG.

Mol Carcinog. 2000 Feb;27(2):76-83.

PMID:
10657900
[PubMed - indexed for MEDLINE]
18.

DNA and protein adduct formation in the colon and blood of humans after exposure to a dietary-relevant dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

Dingley KH, Curtis KD, Nowell S, Felton JS, Lang NP, Turteltaub KW.

Cancer Epidemiol Biomarkers Prev. 1999 Jun;8(6):507-12.

PMID:
10385140
[PubMed - indexed for MEDLINE]
Free Article
19.

Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.

Nelson CP, Kidd LC, Sauvageot J, Isaacs WB, De Marzo AM, Groopman JD, Nelson WG, Kensler TW.

Cancer Res. 2001 Jan 1;61(1):103-9.

PMID:
11196146
[PubMed - indexed for MEDLINE]
Free Article
20.

2,2-bis(4-chlorophenyl)-1,1-dichloroethylene stimulates androgen independence in prostate cancer cells through combinatorial activation of mutant androgen receptor and mitogen-activated protein kinase pathways.

Shah S, Hess-Wilson JK, Webb S, Daly H, Godoy-Tundidor S, Kim J, Boldison J, Daaka Y, Knudsen KE.

Mol Cancer Res. 2008 Sep;6(9):1507-20. doi: 10.1158/1541-7786.MCR-07-2166.

PMID:
18819937
[PubMed - indexed for MEDLINE]
Free Article
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