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Results: 1 to 20 of 267

1.

Inhibition of Notch signaling induces apoptosis of myeloma cells and enhances sensitivity to chemotherapy.

Nefedova Y, Sullivan DM, Bolick SC, Dalton WS, Gabrilovich DI.

Blood. 2008 Feb 15;111(4):2220-9. Epub 2007 Nov 26.

PMID:
18039953
[PubMed - indexed for MEDLINE]
Free Article
2.

Involvement of Notch-1 signaling in bone marrow stroma-mediated de novo drug resistance of myeloma and other malignant lymphoid cell lines.

Nefedova Y, Cheng P, Alsina M, Dalton WS, Gabrilovich DI.

Blood. 2004 May 1;103(9):3503-10. Epub 2003 Dec 11.

PMID:
14670925
[PubMed - indexed for MEDLINE]
Free Article
3.

Dual antitumor mechanisms of Notch signaling inhibitor in a T-cell acute lymphoblastic leukemia xenograft model.

Masuda S, Kumano K, Suzuki T, Tomita T, Iwatsubo T, Natsugari H, Tojo A, Shibutani M, Mitsumori K, Hanazono Y, Ogawa S, Kurokawa M, Chiba S.

Cancer Sci. 2009 Dec;100(12):2444-50. doi: 10.1111/j.1349-7006.2009.01328.x. Epub 2009 Aug 27.

PMID:
19775286
[PubMed - indexed for MEDLINE]
4.

Combined inhibition of Notch signaling and Bcl-2/Bcl-xL results in synergistic antimyeloma effect.

Li M, Chen F, Clifton N, Sullivan DM, Dalton WS, Gabrilovich DI, Nefedova Y.

Mol Cancer Ther. 2010 Dec;9(12):3200-9. doi: 10.1158/1535-7163.MCT-10-0372.

PMID:
21159606
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Notch-regulation upon Dll4-stimulation of TGFb-induced apoptosis and gene expression in human B-cell non-Hodgkin lymphomas.

Hajdu M, Kopper L, Sebestyén A.

Scand J Immunol. 2010 Jan;71(1):29-37. doi: 10.1111/j.1365-3083.2009.02346.x.

PMID:
20017807
[PubMed - indexed for MEDLINE]
6.

Inhibition of gamma-secretase affects proliferation of leukemia and hepatoma cell lines through Notch signaling.

Suwanjunee S, Wongchana W, Palaga T.

Anticancer Drugs. 2008 Jun;19(5):477-86. doi: 10.1097/CAD.0b013e3282fc6cdd.

PMID:
18418214
[PubMed - indexed for MEDLINE]
7.

Anti-Notch treatment prevents multiple myeloma cells localization to the bone marrow via the chemokine system CXCR4/SDF-1.

Mirandola L, Apicella L, Colombo M, Yu Y, Berta DG, Platonova N, Lazzari E, Lancellotti M, Bulfamante G, Cobos E, Chiriva-Internati M, Chiaramonte R.

Leukemia. 2013 Jul;27(7):1558-66. doi: 10.1038/leu.2013.27. Epub 2013 Jan 28.

PMID:
23354012
[PubMed - indexed for MEDLINE]
8.

Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor.

Lan K, Murakami M, Bajaj B, Kaul R, He Z, Gan R, Feldman M, Robertson ES.

Cancer Biol Ther. 2009 Nov;8(22):2136-43. Epub 2009 Nov 7.

PMID:
19783901
[PubMed - indexed for MEDLINE]
Free Article
9.

Downregulation of Notch signaling by gamma-secretase inhibition can abrogate chemotherapy-induced apoptosis in T-ALL cell lines.

Liu S, Breit S, Danckwardt S, Muckenthaler MU, Kulozik AE.

Ann Hematol. 2009 Jul;88(7):613-21. doi: 10.1007/s00277-008-0646-x. Epub 2008 Dec 5.

PMID:
19057901
[PubMed - indexed for MEDLINE]
10.

Evaluation of selective gamma-secretase inhibitor PF-03084014 for its antitumor efficacy and gastrointestinal safety to guide optimal clinical trial design.

Wei P, Walls M, Qiu M, Ding R, Denlinger RH, Wong A, Tsaparikos K, Jani JP, Hosea N, Sands M, Randolph S, Smeal T.

Mol Cancer Ther. 2010 Jun;9(6):1618-28. doi: 10.1158/1535-7163.MCT-10-0034. Epub 2010 Jun 8.

PMID:
20530712
[PubMed - indexed for MEDLINE]
Free Article
11.

MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo.

Hideshima T, Neri P, Tassone P, Yasui H, Ishitsuka K, Raje N, Chauhan D, Podar K, Mitsiades C, Dang L, Munshi N, Richardson P, Schenkein D, Anderson KC.

Clin Cancer Res. 2006 Oct 1;12(19):5887-94.

PMID:
17020997
[PubMed - indexed for MEDLINE]
Free Article
12.

Combination therapy with interleukin-6 receptor superantagonist Sant7 and dexamethasone induces antitumor effects in a novel SCID-hu In vivo model of human multiple myeloma.

Tassone P, Neri P, Burger R, Savino R, Shammas M, Catley L, Podar K, Chauhan D, Masciari S, Gozzini A, Tagliaferri P, Venuta S, Munshi NC, Anderson KC.

Clin Cancer Res. 2005 Jun 1;11(11):4251-8.

PMID:
15930364
[PubMed - indexed for MEDLINE]
Free Article
13.

[Notch signaling pathway and multiple myeloma].

Gan ZH, Chen Y.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2009 Oct;17(5):1380-3. Review. Chinese.

PMID:
19840488
[PubMed - indexed for MEDLINE]
14.

Notch and NOXA-related pathways in melanoma cells.

Nickoloff BJ, Hendrix MJ, Pollock PM, Trent JM, Miele L, Qin JZ.

J Investig Dermatol Symp Proc. 2005 Nov;10(2):95-104. Review.

PMID:
16363061
[PubMed - indexed for MEDLINE]
Free Article
15.

Specific killing of multiple myeloma cells by (-)-epigallocatechin-3-gallate extracted from green tea: biologic activity and therapeutic implications.

Shammas MA, Neri P, Koley H, Batchu RB, Bertheau RC, Munshi V, Prabhala R, Fulciniti M, Tai YT, Treon SP, Goyal RK, Anderson KC, Munshi NC.

Blood. 2006 Oct 15;108(8):2804-10. Epub 2006 Jun 29.

PMID:
16809610
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I).

Jernberg-Wiklund H, Nilsson K.

Adv Cancer Res. 2007;97:139-65. Review.

PMID:
17419944
[PubMed - indexed for MEDLINE]
17.

Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells.

Kogoshi H, Sato T, Koyama T, Nara N, Tohda S.

Oncol Rep. 2007 Jul;18(1):77-80.

PMID:
17549349
[PubMed - indexed for MEDLINE]
18.

γ-Secretase inhibitor enhances antitumour effect of radiation in Notch-expressing lung cancer.

Mizugaki H, Sakakibara-Konishi J, Ikezawa Y, Kikuchi J, Kikuchi E, Oizumi S, Dang TP, Nishimura M.

Br J Cancer. 2012 Jun 5;106(12):1953-9. doi: 10.1038/bjc.2012.178. Epub 2012 May 17.

PMID:
22596234
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells.

Curry CL, Reed LL, Golde TE, Miele L, Nickoloff BJ, Foreman KE.

Oncogene. 2005 Sep 22;24(42):6333-44.

PMID:
15940249
[PubMed - indexed for MEDLINE]
20.

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways.

Lunghi P, Giuliani N, Mazzera L, Lombardi G, Ricca M, Corradi A, Cantoni AM, Salvatore L, Riccioni R, Costanzo A, Testa U, Levrero M, Rizzoli V, Bonati A.

Blood. 2008 Sep 15;112(6):2450-62. doi: 10.1182/blood-2007-10-114348. Epub 2008 Jun 26.

PMID:
18583568
[PubMed - indexed for MEDLINE]
Free Article

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