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Results: 1 to 20 of 118

1.

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.

Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA.

Nature. 2007 Dec 13;450(7172):1106-10. Epub 2007 Nov 21.

PMID:
18033247
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.

Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18993-8. Epub 2007 Nov 19.

PMID:
18025461
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.

Li H, Ilin S, Wang W, Duncan EM, Wysocka J, Allis CD, Patel DJ.

Nature. 2006 Jul 6;442(7098):91-5. Epub 2006 May 21.

PMID:
16728978
[PubMed - indexed for MEDLINE]
4.

A plant homeodomain in RAG-2 that binds Hypermethylated lysine 4 of histone H3 is necessary for efficient antigen-receptor-gene rearrangement.

Liu Y, Subrahmanyam R, Chakraborty T, Sen R, Desiderio S.

Immunity. 2007 Oct;27(4):561-71. Epub 2007 Oct 11.

PMID:
17936034
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.

Peña PV, Davrazou F, Shi X, Walter KL, Verkhusha VV, Gozani O, Zhao R, Kutateladze TG.

Nature. 2006 Jul 6;442(7098):100-3. Epub 2006 May 21.

PMID:
16728977
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Autoinhibition of DNA cleavage mediated by RAG1 and RAG2 is overcome by an epigenetic signal in V(D)J recombination.

Grundy GJ, Yang W, Gellert M.

Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22487-92. doi: 10.1073/pnas.1014958107. Epub 2010 Dec 13.

PMID:
21149691
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The PHD domain of the sea urchin RAG2 homolog, SpRAG2L, recognizes dimethylated lysine 4 in histone H3 tails.

Wilson DR, Norton DD, Fugmann SD.

Dev Comp Immunol. 2008;32(10):1221-30. doi: 10.1016/j.dci.2008.03.012. Epub 2008 May 8.

PMID:
18499250
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Côté J, Chua KF, Gozani O.

Nature. 2006 Jul 6;442(7098):96-9. Epub 2006 May 21.

PMID:
16728974
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination.

West KL, Singha NC, De Ioannes P, Lacomis L, Erdjument-Bromage H, Tempst P, Cortes P.

Immunity. 2005 Aug;23(2):203-12.

PMID:
16111638
[PubMed - indexed for MEDLINE]
Free Article
10.

Analysis of mutations from SCID and Omenn syndrome patients reveals the central role of the Rag2 PHD domain in regulating V(D)J recombination.

Couëdel C, Roman C, Jones A, Vezzoni P, Villa A, Cortes P.

J Clin Invest. 2010 Apr;120(4):1337-44. doi: 10.1172/JCI41305. Epub 2010 Mar 15.

PMID:
20234091
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The roles of the RAG1 and RAG2 "non-core" regions in V(D)J recombination and lymphocyte development.

Jones JM, Simkus C.

Arch Immunol Ther Exp (Warsz). 2009 Mar-Apr;57(2):105-16. doi: 10.1007/s00005-009-0011-3. Epub 2009 Mar 31. Review.

PMID:
19333736
[PubMed - indexed for MEDLINE]
12.

Critical determinants for chromatin binding by Saccharomyces cerevisiae Yng1 exist outside of the plant homeodomain finger.

Chruscicki A, Macdonald VE, Young BP, Loewen CJ, Howe LJ.

Genetics. 2010 Jun;185(2):469-77. doi: 10.1534/genetics.110.116285. Epub 2010 Mar 29.

PMID:
20351216
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

H3K4me3 stimulates the V(D)J RAG complex for both nicking and hairpinning in trans in addition to tethering in cis: implications for translocations.

Shimazaki N, Tsai AG, Lieber MR.

Mol Cell. 2009 Jun 12;34(5):535-44. doi: 10.1016/j.molcel.2009.05.011.

PMID:
19524534
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.

Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD.

Nature. 2009 Jun 11;459(7248):847-51. doi: 10.1038/nature08036.

PMID:
19430464
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A PHD finger motif in the C terminus of RAG2 modulates recombination activity.

Elkin SK, Ivanov D, Ewalt M, Ferguson CG, Hyberts SG, Sun ZY, Prestwich GD, Yuan J, Wagner G, Oettinger MA, Gozani OP.

J Biol Chem. 2005 Aug 5;280(31):28701-10. Epub 2005 Jun 17.

PMID:
15964836
[PubMed - indexed for MEDLINE]
Free Article
16.

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.

Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD.

Nature. 2006 Jul 6;442(7098):86-90. Epub 2006 May 21.

PMID:
16728976
[PubMed - indexed for MEDLINE]
17.

Histone H3R2 symmetric dimethylation and histone H3K4 trimethylation are tightly correlated in eukaryotic genomes.

Yuan CC, Matthews AG, Jin Y, Chen CF, Chapman BA, Ohsumi TK, Glass KC, Kutateladze TG, Borowsky ML, Struhl K, Oettinger MA.

Cell Rep. 2012 Feb 23;1(2):83-90.

PMID:
22720264
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A histone code for regulating V(D)J recombination.

Schlissel MS, Schulz D, Vettermann C.

Mol Cell. 2009 Jun 26;34(6):639-40. doi: 10.1016/j.molcel.2009.06.004.

PMID:
19560416
[PubMed - indexed for MEDLINE]
Free Article
19.

Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b.

Zeng L, Zhang Q, Li S, Plotnikov AN, Walsh MJ, Zhou MM.

Nature. 2010 Jul 8;466(7303):258-62. doi: 10.1038/nature09139.

PMID:
20613843
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36.

Shi X, Kachirskaia I, Walter KL, Kuo JH, Lake A, Davrazou F, Chan SM, Martin DG, Fingerman IM, Briggs SD, Howe L, Utz PJ, Kutateladze TG, Lugovskoy AA, Bedford MT, Gozani O.

J Biol Chem. 2007 Jan 26;282(4):2450-5. Epub 2006 Dec 1.

PMID:
17142463
[PubMed - indexed for MEDLINE]
Free PMC Article

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