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Investigating the function of the putative mycolic acid methyltransferase UmaA: divergence between the Mycobacterium smegmatis and Mycobacterium tuberculosis proteins.

Laval F, Haites R, Movahedzadeh F, Lemassu A, Wong CY, Stoker N, Billman-Jacobe H, Daffé M.

J Biol Chem. 2008 Jan 18;283(3):1419-27. Epub 2007 Nov 15.


Tracking the putative biosynthetic precursors of oxygenated mycolates of Mycobacterium tuberculosis. Structural analysis of fatty acids of a mutant strain deviod of methoxy- and ketomycolates.

Dinadayala P, Laval F, Raynaud C, Lemassu A, Laneelle MA, Laneelle G, Daffe M.

J Biol Chem. 2003 Feb 28;278(9):7310-9. Epub 2002 Dec 6.


Further insight into S-adenosylmethionine-dependent methyltransferases: structural characterization of Hma, an enzyme essential for the biosynthesis of oxygenated mycolic acids in Mycobacterium tuberculosis.

Boissier F, Bardou F, Guillet V, Uttenweiler-Joseph S, Daffé M, Quémard A, Mourey L.

J Biol Chem. 2006 Feb 17;281(7):4434-45. Epub 2005 Dec 15.


Accurate molecular mass determination of mycolic acids by MALDI-TOF mass spectrometry.

Laval F, Lanéelle MA, Déon C, Monsarrat B, Daffé M.

Anal Chem. 2001 Sep 15;73(18):4537-44.


Temperature-dependent regulation of mycolic acid cyclopropanation in saprophytic mycobacteria: role of the Mycobacterium smegmatis 1351 gene (MSMEG_1351) in CIS-cyclopropanation of alpha-mycolates.

Alibaud L, Alahari A, Trivelli X, Ojha AK, Hatfull GF, Guerardel Y, Kremer L.

J Biol Chem. 2010 Jul 9;285(28):21698-707. doi: 10.1074/jbc.M110.125724. Epub 2010 May 10.


Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy.

Gao LY, Laval F, Lawson EH, Groger RK, Woodruff A, Morisaki JH, Cox JS, Daffe M, Brown EJ.

Mol Microbiol. 2003 Sep;49(6):1547-63.


Mycolic acid methyltransferase, MmaA4, is necessary for thiacetazone susceptibility in Mycobacterium tuberculosis.

Alahari A, Alibaud L, Trivelli X, Gupta R, Lamichhane G, Reynolds RC, Bishai WR, Guerardel Y, Kremer L.

Mol Microbiol. 2009 Mar;71(5):1263-77. doi: 10.1111/j.1365-2958.2009.06604.x. Epub 2009 Jan 15.


The reductase that catalyzes mycolic motif synthesis is required for efficient attachment of mycolic acids to arabinogalactan.

Lea-Smith DJ, Pyke JS, Tull D, McConville MJ, Coppel RL, Crellin PK.

J Biol Chem. 2007 Apr 13;282(15):11000-8. Epub 2007 Feb 17.


The Mycobacterium tuberculosis cmaA2 gene encodes a mycolic acid trans-cyclopropane synthetase.

Glickman MS, Cahill SM, Jacobs WR Jr.

J Biol Chem. 2001 Jan 19;276(3):2228-33. Epub 2000 Nov 22.


S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases.

Vaubourgeix J, Bardou F, Boissier F, Julien S, Constant P, Ploux O, Daffé M, Quémard A, Mourey L.

J Biol Chem. 2009 Jul 17;284(29):19321-30. doi: 10.1074/jbc.M809599200. Epub 2009 May 13.


Comprehensive analysis of mycolic acid subclass and molecular species composition of Mycobacterium bovis BCG Tokyo 172 cell wall skeleton (SMP-105).

Uenishi Y, Fujita Y, Kusunose N, Yano I, Sunagawa M.

J Microbiol Methods. 2008 Feb;72(2):149-56. doi: 10.1016/j.mimet.2007.11.016. Epub 2007 Nov 22.


Functional complementation of the essential gene fabG1 of Mycobacterium tuberculosis by Mycobacterium smegmatis fabG but not Escherichia coli fabG.

Parish T, Roberts G, Laval F, Schaeffer M, Daffé M, Duncan K.

J Bacteriol. 2007 May;189(10):3721-8. Epub 2007 Mar 2.


Mycobacterium bovis BCG genes involved in the biosynthesis of cyclopropyl keto- and hydroxy-mycolic acids.

Dubnau E, Lanéelle MA, Soares S, Bénichou A, Vaz T, Promé D, Promé JC, Daffé M, Quémard A.

Mol Microbiol. 1997 Jan;23(2):313-22.


Structure of a hydroxymycolic acid potentially involved in the synthesis of oxygenated mycolic acids of the Mycobacterium tuberculosis complex.

Quémard A, Lanéelle MA, Marrakchi H, Promé D, Dubnau E, Daffé M.

Eur J Biochem. 1997 Dec 15;250(3):758-63.


Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis.

Slayden RA, Lee RE, Armour JW, Cooper AM, Orme IM, Brennan PJ, Besra GS.

Antimicrob Agents Chemother. 1996 Dec;40(12):2813-9.

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