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Results: 1 to 20 of 287

1.

Mutational inactivation of TGFBR2 in microsatellite unstable colon cancer arises from the cooperation of genomic instability and the clonal outgrowth of transforming growth factor beta resistant cells.

Biswas S, Trobridge P, Romero-Gallo J, Billheimer D, Myeroff LL, Willson JK, Markowitz SD, Grady WM.

Genes Chromosomes Cancer. 2008 Feb;47(2):95-106.

PMID:
17985359
[PubMed - indexed for MEDLINE]
2.

Proliferation and Cdk4 expression in microsatellite unstable colon cancers with TGFBR2 mutations.

Grady WM, Willis JE, Trobridge P, Romero-Gallo J, Munoz N, Olechnowicz J, Ferguson K, Gautam S, Markowitz SD.

Int J Cancer. 2006 Feb 1;118(3):600-8.

PMID:
16108056
[PubMed - indexed for MEDLINE]
3.

Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers.

Grady WM, Myeroff LL, Swinler SE, Rajput A, Thiagalingam S, Lutterbaugh JD, Neumann A, Brattain MG, Chang J, Kim SJ, Kinzler KW, Vogelstein B, Willson JK, Markowitz S.

Cancer Res. 1999 Jan 15;59(2):320-4.

PMID:
9927040
[PubMed - indexed for MEDLINE]
Free Article
4.

Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer.

Biswas S, Chytil A, Washington K, Romero-Gallo J, Gorska AE, Wirth PS, Gautam S, Moses HL, Grady WM.

Cancer Res. 2004 Jul 15;64(14):4687-92.

PMID:
15256431
[PubMed - indexed for MEDLINE]
Free Article
5.

Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.

Muñoz NM, Upton M, Rojas A, Washington MK, Lin L, Chytil A, Sozmen EG, Madison BB, Pozzi A, Moon RT, Moses HL, Grady WM.

Cancer Res. 2006 Oct 15;66(20):9837-44.

PMID:
17047044
[PubMed - indexed for MEDLINE]
Free Article
6.
7.

Mutation analysis of the transforming growth factor-beta type II receptor in human cell lines resistant to growth inhibition by transforming growth factor-beta.

Vincent F, Nagashima M, Takenoshita S, Khan MA, Gemma A, Hagiwara K, Bennett WP.

Oncogene. 1997 Jul 3;15(1):117-22.

PMID:
9233784
[PubMed - indexed for MEDLINE]
Free Article
8.

Compensation of loss of protein function in microsatellite-unstable colon cancer cells (HCT116): a gene-dependent effect on the cell surface glycan profile.

Patsos G, André S, Roeckel N, Gromes R, Gebert J, Kopitz J, Gabius HJ.

Glycobiology. 2009 Jul;19(7):726-34. doi: 10.1093/glycob/cwp040. Epub 2009 Mar 17.

PMID:
19293232
[PubMed - indexed for MEDLINE]
Free Article
9.

Microsatellite instability and mutational analysis of transforming growth factor beta receptor type II gene (TGFBR2) in sporadic ovarian cancer.

Alvi AJ, Rader JS, Broggini M, Latif F, Maher ER.

Mol Pathol. 2001 Aug;54(4):240-3.

PMID:
11477138
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mutation analysis of coding sequences of the entire transforming growth factor beta type II receptor gene in sporadic human colon cancer using genomic DNA and intron primers.

Takenoshita S, Tani M, Nagashima M, Hagiwara K, Bennett WP, Yokota J, Harris CC.

Oncogene. 1997 Mar 13;14(10):1255-8.

PMID:
9121777
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

Activin type II receptor restoration in ACVR2-deficient colon cancer cells induces transforming growth factor-beta response pathway genes.

Deacu E, Mori Y, Sato F, Yin J, Olaru A, Sterian A, Xu Y, Wang S, Schulmann K, Berki A, Kan T, Abraham JM, Meltzer SJ.

Cancer Res. 2004 Nov 1;64(21):7690-6.

PMID:
15520171
[PubMed - indexed for MEDLINE]
Free Article
13.

Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers.

Jung B, Doctolero RT, Tajima A, Nguyen AK, Keku T, Sandler RS, Carethers JM.

Gastroenterology. 2004 Mar;126(3):654-9.

PMID:
14988818
[PubMed - indexed for MEDLINE]
14.

Microsatellite instability(MSI) in non-small cell lung cancer(NSCLC) is highly associated with transforming growth factor-beta type II receptor(TGF-beta RII) frameshift mutation.

Kim WS, Park C, Hong SK, Park BK, Kim HS, Park K.

Anticancer Res. 2000 May-Jun;20(3A):1499-502.

PMID:
10928062
[PubMed - indexed for MEDLINE]
15.

Significance of mutations in TGFBR2 and BAX in neoplastic progression and patient outcome in sporadic colorectal tumors with high-frequency microsatellite instability.

Fernández-Peralta AM, Nejda N, Oliart S, Medina V, Azcoita MM, González-Aguilera JJ.

Cancer Genet Cytogenet. 2005 Feb;157(1):18-24.

PMID:
15676142
[PubMed - indexed for MEDLINE]
16.

Transforming growth factor beta receptor 2 (TGFBR2) changes sialylation in the microsatellite unstable (MSI) Colorectal cancer cell line HCT116.

Lee J, Ballikaya S, Schönig K, Ball CR, Glimm H, Kopitz J, Gebert J.

PLoS One. 2013;8(2):e57074. doi: 10.1371/journal.pone.0057074. Epub 2013 Feb 27.

PMID:
23468914
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Microsatellite unstable colorectal cancer cell lines with truncating TGFbetaRII mutations remain sensitive to endogenous TGFbeta.

Baker K, Raut P, Jass JR.

J Pathol. 2007 Nov;213(3):257-65.

PMID:
17893910
[PubMed - indexed for MEDLINE]
18.

Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells.

Wang J, Sun L, Myeroff L, Wang X, Gentry LE, Yang J, Liang J, Zborowska E, Markowitz S, Willson JK, et al.

J Biol Chem. 1995 Sep 15;270(37):22044-9.

PMID:
7665626
[PubMed - indexed for MEDLINE]
Free Article
19.

MSH2-deficient murine lymphomas harbor insertion/deletion mutations in the transforming growth factor beta receptor type 2 gene and display low not high frequency microsatellite instability.

Lowsky R, Magliocco A, Ichinohasama R, Reitmair A, Scott S, Henry M, Kadin ME, DeCoteau JF.

Blood. 2000 Mar 1;95(5):1767-72.

PMID:
10688836
[PubMed - indexed for MEDLINE]
Free Article
20.

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